One Day MD | Evidence-Based Wellness

You’ve probably heard someone say, “Eat your carrots, they’re good for your eyes.” You may have also seen advertisements for nutritional supplements for eye health. Can vitamins and minerals benefit your eye health and vision? Keep reading to learn more about supplements and eye health. What science has to say Plenty of claims are made about the positive effects of supplements on vision and eye health, but very few research studies support these claims. One exception is the Age-Related Eye Disease Studies (AREDS and AREDS2). These are large studies conducted by the National Eye Institute. Results from AREDS 2 took what was learned from AREDS and improved the supplement recommendations. The studies focused on two conditions that affect millions globally, age-related macular degeneration (AMD) and cataracts. Age-related macular degeneration (AMD) AMD is the leading cause of vision loss in the United States. It affects more than 10 million people. It’s mainly associated with...

Abstract Background: Monotherapy approaches in clinical nutrition frequently fail to address the highly integrated metabolic loops governing human physiology. The widespread administration of high-dose Vitamin D3 has exposed a critical clinical vulnerability known as the "Calcium Paradox"—the concurrent development of skeletal mineral deficiencies alongside soft tissue and vascular calcification. Objective: This review maps out the complete systemic, molecular, and genomic interactions of a quadpartite biological network: Cholecalciferol (D3), Menaquinone-7 (K2), Magnesium (Mg), and Retinol (A). Mechanisms: Vitamin D3 acts as the foundational driver of calcium influx. However, its efficiency and safety are entirely dependent on magnesium for enzymatic conversion, Vitamin A for nuclear receptor heterodimerization, and Vitamin K2 for post-translational modification of calcium-binding proteins. Conclusion: To achie...

If you want to fight the physical signs of aging, one of the most recommended nutrients is retinol. Retinol has been considered the gold standard ingredient for reducing the telltale signs of aging such as fine lines, wrinkles, dull skin and large pores.   Read on to learn more about the merits this nutrient can have for your skin, plus safe ways to increase your body's level natural level. Update 2024: Vitamin A Deficiency Promotes Leaky Gut and Alzheimer's   What Is Retinol? You may be surprised to learn that retinol is simply a preformed type of vitamin A (2). It's sometimes called the "true" vitamin A because it's the bioavailable form of this nutrient (3). Vitamin A refers to different kinds of nutrients that can be divided into two major categories: retinoids and carotenoids. Natural retinoids are the fat-soluble, biologically active form of vitamin A that's obtained from animal-based foods, whereas carotenoids are the previtamin A fo...