One Day MD | Evidence-Based Wellness

Scientific Review by the Clinical Editorial Team  |  Published: November 2019  |  Last Reviewed: July 2026   |  Category: Regenerative Medicine | Evidence Review Quick Answer Stem cell research has grown to over 379,000 published studies on PubMed as of mid-2026, but the evidence is not uniform across conditions. Hematopoietic stem cell transplantation for leukemia and lymphoma is decades-old, FDA-licensed standard of care. A donor islet cell therapy, Lantidra , became the first FDA-approved cellular therapy for type 1 diabetes in 2023, and a stem-cell-derived successor, zimislecel , is now in Phase 3 trials. Everything else on this page — stroke, osteoarthritis, spinal cord injury, autoimmune disease, heart disease, autism, anti-aging, hair loss, kidney and liver disease, and back pain — remains investigational, with no FDA-approved stem cell product for these indications. The FDA has repeatedly warned that clinics marketing unapproved st...

By Dr. Frank Yap, MD | Medically reviewed by One Day MD Review Team | Originally published: August 24, 2026 | Last updated: September 29, 2026 Quick Answer: A healthy lifestyle may add years to life, and potentially a decade or more in some populations, but no scientifically valid number applies to everyone. The biggest gains come from not smoking, regular physical activity, a high-quality diet, a healthy body weight, and controlled cardiovascular and metabolic risk factors . One influential U.S. analysis projected about 14 more years for women and 12 for men at age 50 for people with five low-risk habits versus none, but that is an observational estimate, not a guarantee. Supplements and anti-aging drugs are not proven to add a specific number of years. Preventing falls and injury also protects healthspan: balance and strength training is the best-supported strategy. In this guide What the Best Evidence Shows Other Studies Point the Same Way How Much Does Each Lifestyle...