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I-LONGEVITY Protocol: Anti Aging Guide to Help People Prevent and Reverse Aging (2025)

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Table of Contents Methodology What is Aging? Biological Age vs Chronological Age Causes of Aging and Hallmarks of Aging What is Cell Senescence? What is Epigenetics? Diet and Lifestyle for Anti Aging Avoid Sugar and Ultra-processed Foods Mediterranean Diet and Vegetables Avoid Smoking and Alcohol Avoid Linoleic Acid (Omega-6 Fatty Acids) and Vegetable Oil Quality Sleep Exercise, Resistance Training and Walking Stress Management Social Support Caloric Restriction, Intermittent fasting (Time Restricted Eating) and Fasting Best Scientifically Proven Anti Aging Supplements Vitamin D3 and K2 Glycine, NAC and Taurine B Vitamins, Nicotinamide mononucleotide (NMN) and NAD Boosting Supplements Omega-3 fatty acids Magnesium and Molecular Hydrogen Curcumin (Turmeric) CoQ10 Vitamin C Zinc EGCG (Green Tea) Lutein and Zeaxanthin Glucosamine and Chondroitin Protein Powder and Collagen Spermidine Crocin (Saffron) Cocoa Creatine Melatonin Garlic Other Promising Interventions for Longevity Stem Cell The...
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16 Best Vitamin D3 Supplements of 2025

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A. Introduction Vitamin D is a fat-soluble vitamin, which means it dissolves in fats and oils and can be stored in your body’s fatty tissues and liver for extended periods.  Unlike other vitamins, vitamin D acts like a hormone, binding to receptors in nearly every cell. This explains its widespread impact on health. Scientists continue to uncover its wide-ranging effects, with  over 100,000 studies on PubMed since 1964 exploring its benefits . Vitamin D is essential for.. ✅ Calcium absorption – Critical for strong bones and teeth ✅ Muscle function – Helps prevent weakness and cramps ✅ Nerve signaling – Supports brain-body communication ✅ Immune defense – Fights infections and reduces inflammation ✅ Hormone regulation – Influences mood, metabolism, and more B. What is Vitamin D Good For? by labdoor.com 1. Bone Health Vitamin D plays a crucial role in calcium absorption and bone metabolism. It's essential for the prevention of conditions like osteoporosis and osteomalacia, co...
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NAC vs NAD vs NR vs NMN vs Niacin: What Are the Differences?

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NAC vs NAD vs Niacin vs NR vs NMN . Due to the small alphabetical differences, these supplements are often mixed up and confused by most consumers. We will cover the essentials and explain about each of these supplements below. Contents NAD NAD vs NAD+ NAD+ for Anti Aging NAD+ Helps Restore Age-Related Muscle Deterioration NAD and Resveratrol NAD Supplements NAC Niacin (NA) NR NMN NAC vs NMN Gluthatione vs NAC NAC vs Niacin NR vs NMN Can you take NR and NMN together? Niacin vs NR vs NMN Stability and Storage of NMN and NR Naturally Boosting NAD Levels Related Articles NAD NAD is a type of coenzyme found in all living cells. NAD plays important roles in a variety of metabolic reactions, including energy production and DNA repair. NAD is derived from Nicotinamide Riboside (NR) and various other precu...
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18 Best Supplements to Reduce Cytokine Storm: Advanced Guide

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As of May 2024, there are more than 4,000 early treatment studies  that have been published and shared with the whole world. New ones are being added every day.  This is a review of the literature, covering multiple observational studies, randomized controlled trials and references related to natural supplements and cytokine storm with more than 300 studies and references. We know that while a large percentage of the population only experiences mild to moderate symptoms of COVID-19 and won’t require hospitalization, others experience severe symptoms and complications, require hospitalization, or may even die.  It appears one of the differences between those who have a mild illness and severe illness is related to the body's ability to reduce the hyperimmune response that leads to a cytokine storm and the hyper-coagulability (tendency for blood clots) that often accompanies it. The cytokine storm may be one possible way to ex...
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12 Best Heavy Metal Detox Supplements of 2025

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Detoxifying the body from heavy metals can be an important step in maintaining overall health and wellness. Heavy metals such as lead, mercury, and cadmium can accumulate in the body over time and can have negative effects on the brain, heart, kidneys, and other organs. Some people may be at higher risk of exposure to heavy metals due to their occupation or lifestyle. One way to detoxify the body from heavy metals is through the use of supplements. These supplements can come in various forms such as capsules, tablets, or powders and contain ingredients like chelating agents, antioxidants and natural herbs that work together to remove heavy metals from the body. These supplements are not a substitute for a healthy diet and should be used in conjunction with other healthy lifestyle choices. It's important to note that the effectiveness of heavy metal detox supplements can vary and it's always recommended to consult with a healthcare provider or a qualified practitioner before tak...
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Bryan Johnson's Supplements List (2025): Insider's Guide

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Bryan Johnson, 46, is an ultra-wealthy software entrepreneur who has more than 30 doctors and health experts monitoring his every bodily function. The team, led by 29-year-old regenerative medicine physician Dr.  Oliver Zolman , has committed to help  reverse the aging process  in every one of Johnson’s organs.  Zolman and Johnson obsessively read the scientific literature on aging and longevity and use Bryan Johnson as a guinea pig for the most promising treatments, tracking the results every way they know how. Getting the program up and running required an investment of several million dollars, including the costs of a medical suite at Johnson’s home in Venice, California. This year, he’s on track to spend at least $2 million on his body. He wants to have the brain, heart, lungs, liver, kidneys, tendons, teeth, skin, hair, bladder, penis and rectum of an 18-year-old. Bryan Johnson attributes much of his good health to the benefit...
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Dr. Zelenko's Z-Stack Vitamin Cocktail: Review 2024

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The  Zelenko COVID-19 Protocols  was developed by Dr Vladimir Zelenko. The protocol has as its centerpiece, but not exclusive piece, the combined use of Hydroxychloroquine (HCQ) and Zinc as a means by which a person can both help to prevent or mitigate the contraction of  COVID-19 , or can actually treat the disease once it has been diagnosed.  A  retrospective study  analyzing Dr Zelenko's patient data was accepted for publication after a rigorous peer review process. The study finds that early intervention and treatment of high-risk patients with COVID-19 resulted in significantly fewer hospitalizations and deaths. The treatment consisting of zinc, low-dose hydroxychloroquine (HCQ), and azithromycin, is also referred to as "The Zelenko Protocol." Dr Zelenko has since updated his protocols to incorporate new evidence. He has since evolved his protocols to include a quercetin, zinc, vitamin D and C protocol for low-ris...
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PicoWay vs PicoSure vs PicoPlus vs PicoCare: What are the Differences?

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If you are confused about all the pico laser treatments in town and are looking for a guide to better understand pico laser and pigmentation treatment, you've come to the right place. “Pico Laser” is a recent buzzword in aesthetic medicine, so it's no surprise that Pico Lasers are one of the most popular treatment nowadays. However, the science is also mixed with hype and you are likely to get overwhelmed and cluttered over this Pico Laser treatment. We have compiled related pico laser questions and answers in one place in order to answer the above question and to de-clutter your mind. All answers are provided by medical doctors and dermatologists. The information below is based on published answers from major sites on the internet. Here is the list: Q: I am looking for a treatment for melasma, pore size reduction and rejuvenation. I came across pico technology but what is the difference between Pico Way and Pico Sure ( apart from a manufacturer). Is one better than the...
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10 Best NMN Supplements (2025 Review)

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NMN stands for nicotinamide mononucleotide and is a precursor to NAD+, or nicotinamide adenine dinucleotide. NMN is the direct precursor of the essential molecule nicotinamide adenine dinucleotide (NAD+) and is considered a key component to increase NAD+ levels in cells. NAD+ is a critical molecule found in every cell of your body, but levels of NAD+ naturally fall with age, making it — and NMN, as a result — crucial. NMN is one of the most popular supplements in the anti aging community. The global Nicotinamide Mononucleotide (NMN) market was valued at US$ 98.5 million in 2019 and it is expected to reach US$ 296.5 million ( R ) by the end of 2026, growing at a CAGR (Compound Annual Growth Rate) of 7.3% during 2021-2026. The NAD story took off toward the end of 2013 with a  high-profile paper  by Harvard's David Sinclair and colleagues. Sinclair, recall, achieved fame in the mid-2000s for research on yeast and mice that suggested the red wine ing...
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Exosomes vs PRP Therapy vs Stem Cells: What's the Difference? (2025 Edition)

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In these past few years, stem cells, PRP (platelet-rich plasma) and exosomes have been hot topics among researchers and doctors. However, these forms of treatments are often mixed up and are confusing for most average consumers.  As of February 2025, there are  more than 300,000 studies  related to "stem cell",  more than 30,000 studies  published related to exosome and  more than 14,000 studies  related to PRP on PubMed (US NIH Library of Medicine Database).  Nevertheless, stem cell, PRP and exosome-related therapies are not yet established as standard treatments, given their relatively recent emergence. Regenerative medicine is also becoming a buzzword in the medical community. Why? Because the human body is specially equipped to heal itself, and regenerative therapies tap into this powerful ability. Regenerative medicine includes treatments like stem cell therapy, exosome therapy and platelet-rich plasma (PRP) therapy. Res...
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