12 Best Vitamin D3 Supplements and Reviews of 2022

What Is Vitamin D?

Vitamin D is a fat-soluble vitamin, meaning that it dissolves in fats and oils and can be stored in your body for a long time.

Two main dietary forms exist (Am J Clin Nutr. 2012):
  • Vitamin D3 (cholecalciferol). Found in some animal foods, like fatty fish and egg yolks.
  • Vitamin D2 (ergocalciferol). Found in some plants, mushrooms, and yeasts.

What is Vitamin D Good For?

Vitamin D helps keep you bones strong by aiding in the absorption of calcium and phosphorus. It's involved in maintaining a healthy immune system, mood regulation, heart health, and even weight loss


What is the Best Form of Vitamin D?

Vitamin D is a fat-soluble vitamin, meaning that it does not dissolve in water and is absorbed best in your bloodstream when paired with high-fat foods. For this reason, it's recommended to take vitamin D supplements with a meal to enhance absorption.

Both vitamin D2 and D3 are effectively absorbed into the bloodstream. However, vitamin D2 and D3 are not equal equal when it comes to raising your vitamin D status. Of the two, D3 (cholecalciferol) seems to be almost twice as effective at increasing blood levels of vitamin D as D2 (ergocalciferol) (RR). 

Which form of vitamin D is best absorbed? In one study, the microencapsulated form of vitamin D was the most bioavailable. 

Is vitamin D better absorbed in liquid form? Although no studies have been conducted specifically on liquid vitamin D-3, liquid supplements are considered more bioavailable.

For even better absorption of vitamin D, you must include vitamin K, magnesium, and zinc in your diet. They speed up the absorption procedure and reduce your likelihood of being vitamin D deficient.


Vitamin D2 vs Vitamin D3

vitamin D3 vs D2

Several publications and studies have suggested that maintaining adequate levels of vitamin D would seem potentially beneficial in fighting the COVID-19 infection.


What is the Best Strength of Vitamin D to Take?

How much vitamin D3 is recommended? Consuming 400–800 IU (10–20 mcg) of vitamin D should meet the needs of 97–98% of healthy people. However, several studies show that taking more than this is linked to greater health benefits.

These research implies that consuming 1,000–4,000 IU (25–100 mcg) of vitamin D daily should be ideal for most people to reach healthy vitamin D blood levels.

However, don’t consume more than 4,000 IU of vitamin D without your doctor’s permission. It exceeds the safe upper limits of intake and is not linked to more health benefits.

Best Vitamin D3 Supplement Brands in 2022

If you are looking for the best vitamin D3 supplement, we have done our research and shortlisted the best for you. The list is based on recommendations by third party organizations, online reviews and popularity on search results and forums. Although there are many vitamin D supplement customer reviews on many online sites, we have curated some of the helpful ones below.

Here are the best vitamin D3 supplements that you can buy over the counter or online today.

1. NatureWise Vitamin D3 1,000 iu (25 mcg)


#1 in Vitamin D Supplements of Amazon Best Sellers.
4.8 out of 5 - more than 130,000 global ratings

About this item
  • MOST ACTIVE FORM: NatureWise Vitamin D3 in organic olive oil helps to support the health of teeth and bones, provide immune support, and promote proper muscle function.
  • RECOMMENDED DOSE FOR KIDS & MOMS: 1000IU is the recommended amount of vitamin D3 for growing children and expecting mothers, but our product is intended to safely encourage calcium absorption and immune system strength in any user.
  • SUNSHINE IN A BOTTLE: The Vitamin Council recommends daily vitamin D supplementation for most adults to achieve and maintain optimal levels, regardless of weather or season.
  • ESSENTIAL VITAMIN: Our formula delivers the same biologically active form of vitamin D that the body produces as a result of sun exposure, without the harmful of UVB rays.
  • ENHANCED ABSORPTION: Our Vitamin D 1000 IU softgels are easy to swallow. Some studies indicate that vitamin D3 in liquid softgel form is more bioavailable than powdered or tablet forms.

2. Vitamin K2 + D3 with Organic Virgin Coconut Oil | Vegan D3 (Vitamin D3 5000 iu) with MK7 Vitamin K2 (100mcg) from Chickpea | Non-GMO & Vegan Certified 



#2 Best Seller in Vitamin D Supplements (Amazon Best Sellers).
  • Contains vegan vitamin D3 5000 IU (125 mcg) & 100 mcg of Vitamin K2 as MK-7
  • Made with Vitashine D3 - a patent, plant based form of Vitamin D3 from Lichen and MenaQ7 - a patent form of MK7 from Chickpea
  • 100% Plant based - Vegan Certified & Non-GMO Verified. Soy, Gluten, Gelatin & Carrageenan free
  • Formulated with Organic Coconut Oil - Note: Capsules may appear 'cloudy' due to the Coconut Oil

3. Nature Made Vitamin D3


#1 Pharmacist Recommended
85.9% Labdoor Score

Vitamin D by Nature Made come in various dose strengths:
Moreover, Gluten-free dietary supplements made with high-quality ingredients, these Vitamin D3 supplements have no added color or artificial flavors. These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease

Ratings: 4.8 out of 5 – more than 20,000 global ratings.

Review
I work the midnight shift and I’m living a vampire lifestyle. The only sunlight I get is on my days off or driving home in the morning. This vitamin has definitely offset my deficiency. I noticed more of an energy.

4. Bronson Vitamin K2 (MK7) with D3 Supplement Bone and Heart Health Non-GMO Formula 5000 IU



- Amazon Best Sellers: #11 in Vitamin D Supplements
- Amazon Customer Reviews: 4.8 out of 5 (more than 12,000 ratings)
- Bronson vitamin D3 supplements are available in different doses: 2,000 IU, 5,000 IU and 10,000 IU.
- Warning: Bronson organic vitamin D3 supplement 10,000 IU is a high dose vitamin D3 supplement.  Do not take this dose unless instructed and monitored by your healthcare professional.

5. Vitamin D by Nature’s Bounty for Immune Support


Price: $17.10 > Check Price on Amazon

More than 14,000 customer reviews and a 4.8 out of 5 overall rating on Amazon. 
#12 in Vitamin D Supplements of Amazon Best Sellers.
  • Immune support: 350-count, 2,000 IU Vitamin D3 Softgels for immune health. Vitamin D by Nature’s Bounty may assist the immune system by helping to regulate T and B-lymphocytes. Vitamin D3 is a more potent form of Vitamin D.
  • Strong, healthy bones: In addition to immune support, getting a sufficient amount of Vitamin D is critical to building and maintaining strong bones in adults. It is essential for calcium absorption to help support healthy bones. Nature’s Bounty Vitamin D3 Softgels supplement the Vitamin D your body needs for overall health.
  • Year-round support: Vitamin D3 supplements by Nature’s Bounty contain the same form of Vitamin D that is naturally formed in the body through exposure to sunshine. Nature’s Bounty Vitamin D3 helps replicate the benefits of natural sunshine all year long.
  • Purity is our priority: Nature’s Bounty is committed to safety and purity in all our supplements. Our rapid release Vitamin D3 Softgels are non-GMO, gluten- and sugar-free, and contain no artificial colors, or sweeteners.
  • From the trusted wellness experts: Nature’s Bounty Vitamin D supplements are a product of 50 years of dedication to quality, consistency and scientific research to make vitamins and nutritional supplements of unrivaled excellence.
Vitamin D by Nature's Bounty also come in various other doses:

6. Bronson Vitamin D3 2,000 IU - Best Organic Vitamin D3 Supplement


- Amazon Customer Reviews: 4.7 out of 5 (more than 2,000 ratings)
- Bronson vitamin D3 supplements are available in different doses: 2,000 IU, 5,000 IU and 10,000 IU. We recommend taking the lower dose (2,000 IU) for long term maintenance unless your doctor recommends otherwise.

7. Z-Stack Vitamin D3 2,500 IU, Quercetin 500 mg with Zinc and Vitamin C

Where to buy Z-StackZ Stack Supplement 
Note: To get 5% OFF, use this coupon code: DRFRANCIS
In an effort to make it easier for his patients, Dr Zelenko has developed an oral supplement that contains four key ingredients including quercetin (a zinc ionophore) in combination with zinc, vitamin C and vitamin D3. It’s referred to as 'Z-Stack Supplement'. 

Each capsule contains 250 mg of quercetin, 15 mg of zinc, 2,500 IU of vitamin D3 and 400 mg of vitamin C. Cost per capsule: $0.83.

Z-Stack Vitamin cocktail provides key ingredients needed in order to help your body fight off this deadly invader. The Z-Stack Vitamins are Kosher certified, GMP certified and made in the USA.

Vitamin D is essential to a healthy immune system as it initiates the adaptive immune response. Clinical trial data shows that Vitamin D supplementation is safe and protects against acute respiratory tract infection mortality whereas low levels of vitamin D are associated with higher risk for infection and mortality (bmj.com). 

Quercetin is a zinc ionophore. Meaning it transports zinc into the cells. 

It is known that zinc will slow down the replication of coronavirus through inhibition of enzyme RNA dependent RNA polymerase (PubMed 2010). The COVID-19 virus is a single stranded RNA (RiboNucleicAcid) virus and requires the RNA polymerase to replicate. 

Vitamin C and quercetin co-administration exerts a synergistic antiviral action due to overlapping antiviral and immunomodulatory properties and the capacity of ascorbate to recycle quercetin, increasing its efficacy.

Customer Review on ZStackLife:
My father and I have been taking Z Stack for 4 months. My wife has not. She came down with C-19. I still slept in the same bed with her and neither my father nor I got sick. She started the protocol and was fine in a few days. I'm sold on this product. - Feb 4, 2022

Related Evidence:
  • What is the Zelenko protocol? The Zelenko COVID-19 Protocol was developed by Dr Vladimir Zelenko. A retrospective study analyzing Dr Zelenko's patient data was accepted for publication in the International Journal of Antimicrobial Agents after a rigorous peer review process. The study finds that early intervention and treatment of high-risk patients with COVID-19 resulted in significantly fewer hospitalizations and deaths. The treatment consisting of zinc, low-dose hydroxychloroquine (HCQ), and azithromycin, is also referred to as "The Zelenko Protocol." Dr Zelenko has since updated his protocols to incorporate new evidence.

8. Dr. Mercola Liposomal Vitamin D3

  • Unlike many other vitamin D supplements that are often the inferior D2 form, ergocalciferol, our Liposomal Vitamin D3 is the preferred form – vitamin D3, cholecalciferol.
  • Our formula contains phospholipids from sunflower lecithin that create liposomes in your gastrointestinal tract to help the vitamin D3 molecules gain entry across your gut membrane to its target organs and cells.*
  • They are packed in tightly sealed Licaps® hard-shelled capsules rather than oxygen-permeable soft gels to help avoid leakage and to maintain freshness.
*These statements have not been evaluated by the Food and Drug Administration.

These products are not intended to diagnose, treat, cure, or prevent any disease.

Amazon Ratings: 4.8 out of 5 - more than 550 ratings.

Related Products for Immune Support:

9. NOW Foods Chewable Vitamin D3 5,000 IU - Best Chewable

SHOP NOW ON AMAZON

#26 in Vitamin D Supplements of Amazon Best Sellers.

Dosage: 1 chewable tablet contains 5,000 IU of D3
Price: From $13.68

Some people prefer chewable vitamins over capsules, liquids, gummies and pills. Yet, most chewables contain added sugar.

Unlike other chewable vitamin D supplements, NOW’s Chewable Vitamin D3 5,000 IU is sweetened with xylitol and sorbitol — two sugar alcohols — and natural vanilla and peppermint flavors, making it an excellent choice.

Note that sugar alcohols can cause digestive problems, such as stomach upset and diarrhea, especially when consumed in large amounts. Also, this supplement is held together with cellulose, making it less absorbable than oil-based capsules.

10. Now Foods Vitamin D3 & K2 (120 Veg Caps)

 
Buy on Amazon
  • Also has 3 mg of vitamin C per veg capsule
  • Supports Bone Health
  • Plus Cardiovascular Support
  • Non-GMO
  • Family Owned Since 1968
  • GMP Quality Assured
Dose Strength - 1,000 IU (D3 / K2)

Ordering second bottle now! Started take 2000mg along with magnesium. Hair loss stopped. No more mood Swings and no longer tired.

4.8 out of 5 - more than 5,000 global ratings
#41 in Vitamin D Supplements of Amazon Best Sellers.

Note: Most of the Top 10 Vitamin D supplements as listed on the Amazon Best Sellers have doses that exceed the maximum recommended dose (In USA and UK) of Vitamin D of 4,000 IU. Most of the brands also come in different doses. Do check the label before you purchase.


11. One A Day Women’s Multivitamin (Best Vitamin D for Women)


Buy on Amazon

One a day women's multivitamin is a complete multivitamin specially designed for the leading concerns of women like bone health.
  • Contains key nutrients like vitamins A, B6, C, D, E, and K, riboflavin, thiamin, zinc and niacin
  • Formulated to support: Bone health, immune health, skin health, heart health, and physical energy by helping convert food to fuel.
  • Adult women should take one tablet daily with food
  • Free of gluten, wheat, dairy, artificial flavors, and artificial sweeteners
  • Soy free
  • 200 counts
Dose
Vitamin D3 - 25mcg (1 Tablet)
Vitamin K2 - 25mcg (1 Tablet)

Ratings: 4.8 out of 5 - more than 8,000 global ratings

Review
You need to take them with a meal, real food. Not a light breakfast or a snack. Maybe other vitamins you can get away with that, but these are packed with almost everything you need and more. It requires more than light food. When I first took them in the morning I was sick to my stomach. I've since taken them in the afternoon with lunch usually. I've never had any issues and these vitamins really do make me feel good/healthy

12. Kirkland Signature Maximum Strength Vitamin D3 2000 I.U.


#1 Brand for Vitamin D based on ConsumerLab.com 2022 survey.

Amazon Reviews: 4.8 out of 5 - more than 5,000 global ratings.

Best Vitamin D Foods?

Here is the vitamin D3 content of a few of the best food sources (nih.gov):
  • Salmon, cooked, 3 ounces (85 grams) 447 IU / 11 mcg (75% of RDI)
  • Tuna, canned in water, 3 ounces (85 grams) 154 IU / 4 mcg (26% of RDI)
  • Beef liver, cooked, 3 ounces (85 grams) 42 IU / 1 mcg (7% of RDI)
  • 1 large whole egg (D is found in yolk) 41 IU / 1 mcg (7% of RDI)
  • 1 sardine, canned in oil, drained 23 IU / 0.6 mcg (4% of RDI)
Although fatty fish like salmon, mackerel, swordfish, trout, tuna, and sardines are decent sources, you would have to eat them almost every day to get enough.

According to the United States Department of Agriculture (USDA) Food Composition Database, one 3.5-ounce (100-gram) serving of farmed Atlantic salmon contains 526 IU of vitamin D, or 66% of the DV (Trusted Source).

If you don’t like fish, taking cod liver oil is another way to get nutrients that are hard to get otherwise.

It’s an excellent source of vitamin D. At about 450 IU per teaspoon (4.9 mL), it clocks in at a massive 56% of the DV. It has been used for many years to treat vitamin D deficiency. It also has a history of being used as part of treating rickets, psoriasis, and tuberculosis (Trusted Source, Trusted Source).

Cod liver oil is also very high in vitamin A, with 150% of the DV in just a single teaspoon (4.9 mL). Vitamin A can be toxic in high amounts. The safe upper limit (UL) for vitamin A is 3,000 mcg. A single teaspoon (4.9 mL) of cod liver oil contains 1,350 mcg of vitamin A.

Make sure that you aren’t exceeding the upper limit with cod liver oil or any other vitamin A supplements (Trusted Source, Trusted Source).

In addition, cod liver oil is high in omega-3 fatty acids. Omega-3s may play a role in heart health and may reduce inflammation in the body. Along with fatty fish, cod liver oil is another source of these fatty acids. If you don’t eat fish, it can be hard to get enough omega-3 in your diet (Trusted Source).

Keep in mind that dairy products and cereals are often fortified with vitamin D (Source).

Some rare mushrooms also harbor vitamin D, and egg yolks contain small amounts. The yolk from one large egg contains 37 IU of vitamin D, or 5% of the DV (Trusted Source).

Best Vitamin D Supplement for Absorption

Vitamin D is a fat-soluble vitamin, meaning that it does not dissolve in water and is absorbed best in your bloodstream when paired with high-fat foods.

For this reason, it’s recommended to take vitamin D supplements with a meal to enhance absorption.

According to one study in 17 people, taking vitamin D with the largest meal of the day increased vitamin D blood levels by about 50% after just 2–3 months (NIH).

In another study in 50 older adults, consuming vitamin D alongside a fat-heavy meal increased vitamin D blood levels by 32% after 12 hours compared to a fat-free meal (NIH).

Avocados, nuts, seeds, full-fat dairy products and eggs are nutritious sources of fat that help boost your vitamin D absorption.

What Does Vitamin D Do For Men?

Vitamin D is essential for muscle development as it is involved in the development of skeletal muscle.

Vitamin D also plays an essential role in men’s sexual function and testosterone levels. Healthy levels of vitamin D may also benefit sexual health by mitigating the risk of cardiovascular disease.

Does Vitamin D Help Lose Belly Fat?

Yes, Vitamin D can help trigger weight loss primarily in the belly. This is because Vitamin D and Calcium may work synergistically to reduce the production of cortisol, which is a stress hormone that causes you to store belly fat.

Vitamin D for Acne

Acne is a common and complex skin disorder that can be stressful for many patients due to its chronicity. Although acne is caused by a number of factors, but chronic inflammation is an important mechanism.

According to a study, vitamin D has an immune regulatory function in sebocytes, implying that vitamin D may have anti-inflammatory properties in acne patients.

Vitamin D for Skin Health

Apart from its role in maintaining bone health, vitamin D also has a role in maintaining skin health. 

Vitamin D for Dry or Itchy Skin
Severe dryness of the skin or Itchy skin can be an indicator of Vitamin D deficiency. Getting enough Vitamin D can improve symptoms of skin disorders that cause dry, itchy skin.

Vitamin D and Psoriasis
Nutritionists are particularly interested in vitamin D supplementation for these two reasons. First, oral vitamin D supplementation is an important supplementary therapeutic choice for psoriatic patients. Second, vitamin D supplementation may be crucial in preventing psoriasis-related comorbidity, hypertension, and metabolic syndrome.

Vitamin D and Vitiligo
According to one study, high-dose vitamin D therapy may be both safe and beneficial in the treatment of vitiligo. Sixteen vitiligo patients with low vitamin D status were given 35,000 IU per day for six months, along with a dairy and calcium-rich food limitation and minimum hydration of 2.5 L per day. And the outcome, fourteen of them had re-pigmentation ranging from 25 to 75%. It’s still uncertain if high-dose supplementation provides any benefits for long-term patients with vitiligo.

Vitamin D and Atopic Dermatitis
Vitamin D may play a role in improving the symptoms of Atopic Dermatitis. The findings of this study imply that vitamin D supplementation may help reduce the severity of atopic dermatitis and can be considered as safe and manageable treatment option. However, this conclusion still needs larger-scale studies over a longer duration of treatment.

Vitamin D for cancer prevention and healing

In 2016, a landmark study published in PLOS ONE found that women over 55 with blood concentrations of vitamin D higher than 40 ng/ml, had a 67% lower risk of cancer compared women with levels lower than 20 ng/ml.

Vitamin D Needs Are Underestimated by a Factor of 10

Please remember that sun exposure is the ideal way to optimize your vitamin D status. Not only does sun exposure on enough of your skin increase vitamin D, but it also structures the water in your cells, metabolizes vitamin A so it can improve your immune function, increases nitric oxide, and most importantly will increase the vitally important antioxidant. melatonin, in your mitochondria to reduce oxidative stress and preserve your cellular energy production systems.

It is imperative that you do whatever it takes to work up to one hour of sun exposure every day. If you don't live in an area where this is possible, I strongly encourage you to use this as an excuse to move. Yes, if you value your health, it is that important. Florida is a great option for many as not only is it the sunshine state but it is the state most committed to resisting tyranny.

If you do choose to supplement with vitamin D, understand it is a far inferior option. You will also need to use the correct dose. Many studies consider a "high dose" — 2,000 International Units (IUs) a day, which is not a high dose at all. In fact, it's completely inadequate for most people. Research has found a sixfold variability in dosage response (R), meaning one person taking 5,000 IUs of vitamin D per day may achieve a level of just 20 ng/mL (50 nmol/L) while another is able to reach a level of 120 ng/mL (300 nmol/L) taking the same amount.

This is why it's so important to get your vitamin D level tested at regular intervals. You simply cannot go by dosage. In reality, you should take whatever dosage required to get the vitamin D level in your blood into a healthy range.

According to a study in Anticancer Research (R), it would require 9,600 IUs of vitamin D per day to get a majority (97.5%) of the population to reach 40 ng/mL (100 nmol/L), which research suggests is the very low end of sufficiency (R). That's a far cry from the 600 IUs recommended by the Institute of Medicine (IOM).

What's more, science has shown 20 ng/mL (50 nmol/L), which is typically considered the cutoff for sufficiency, is still grossly inadequate and dangerous to health. For optimal disease protection, you need a vitamin D blood level between 60 to 80 ng/mL19 (150 to 200 nmol/L).

Once you get above 60 ng/mL, the risk for cancer and other chronic illness declines dramatically — in the case of breast cancer by more than 80% (R). The VITAL study and others like it simply did not give participants high-enough doses to get them into a protective range.

One reason why the public has been misled on the issue of dosage stems from a simple mathematical error that has never been corrected. As pointed out in a 2014 paper, the IOM actually underestimates the need by a factor of 10 due to a simple mathematical error. If this error in calculation were to be corrected, the official IOM recommendation would actually be 6,000 IUs a day, not 600 IUs.

You can use this simple tool from GrassrootsHealth to calculate the estimated additional vitamin D intake needed to reach your targeted vitamin D serum level.

According to data published in the Archives of Internal Medicine, 75% of American adults and teens are deficient in vitamin D, based on a sufficiency level of 30 ng/mL. If the sufficiency cutoff were to be moved to 40 or 60 ng/mL, deficiency rates in the U.S. would likely be in the high 90% bracket.

Even with a sufficiency level of 30 ng/mL, 97% of African-Americans and 90% of Mexican-Americans are deficient in this crucial nutrient, which places them at increased risk of chronic disease. Remember it is best to optimize your vitamin D levels with sunshine, NOT oral supplements.

How Much Vitamin D Can You Make and When?

Our skin pigmentations are linked to ancestral latitudinal proximities that optimized our ancestors' skin for sun exposure. The further from the equator our ancestors lived, the lighter their skin, allowing them to biologically maximize the limited availability of the sun, and UV light specifically.

Remember: Your body produces vitamin D through exposure to UVB light. For those living in northern latitudes, this may only be an option for a few short months each year. As a general rule, you have to live below 22 degrees' latitude if you want to produce any vitamin D at all during the winter. 

Prioritizing Nonlethal Melanoma Is Ill-Advised

For decades, the concern over skin cancers, most of which are nonlethal, has taken the front seat. As a result, other far more serious chronic health conditions such as depression, heart disease and internal cancers that claim far more lives than melanoma have been allowed to proliferate. It's high time we straighten our priorities.

The evidence in support of vitamin D optimization is overwhelming, and becomes all the more compelling when the blood level is the primary parameter being measured and tracked.

Overall, research supports the idea that higher levels offer greater cancer protection, and even levels as high as 100 ng/mL appear safe and beneficial. Importantly, having a serum vitamin D level of 60 ng/mL has been shown to positively impact anyone with breast cancer or diabetes (both Type 1 and Type 2), as well as pregnant women and lactating mothers.

In short, the recommendation to avoid sun exposure at all costs is inadvertently killing people while saving very few if any from deadly melanoma. Outside magazine likens it to the public health recommendation to trade saturated fat for trans fats — a public health policy that has since been found to have killed millions by causing the very problem it aimed to prevent.

Remember, the only way to ensure vitamin D sufficiency is to get tested, and then get sensible sun exposure along with a sufficiently high dose of vitamin D3 if needed, to get you into the 60 to 80 ng/mL range. It's time for the U.S., Canada and other nations to acknowledge the science backing sensible sun exposure recommendations, such as those by Australia's Cancer Council, which states:

"Ultraviolet radiation from the sun has both beneficial and harmful effects on human health … A balance is required between excessive exposure which increases the risk of skin cancer and enough sun exposure to maintain adequate vitamin D levels …

It should be noted that the benefits of sun exposure may extend beyond the production of vitamin D. Other possible beneficial effects of sun exposure … include reduction in blood pressure, suppression of autoimmune disease, and improvements in mood." 


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