GLP-1 Advisor | One Day MD

Home › GLP-1 Hub By Dr. Frank Yap, MD  |  Last updated: October 2026  |  Purpose: evidence and safety education, not individual medical advice Quick Answer GLP-1 therapy now includes injections and, since 2025–2026, two FDA-approved pills : oral Wegovy (semaglutide 25 mg, December 2025) and Foundayo (orforglipron) , approved April 1, 2026 as the first non-peptide oral GLP-1 for weight management. Retatrutide is not approved anywhere ; it remains in Phase 3 testing. Compounded and gray-market GLP-1 or peptide products are not FDA-approved, and the FDA issued warning letters to telehealth compounders in March 2026. Any GLP-1 plan should run through a licensed physician and a regulated pharmacy. On this page Approval status at a glance Pills vs injections Retatrutide: what is and isn't known Safety, side effects and compounding risks Evidence grades (CEBM) Explore the full GLP-1 & peptide library Using this hub with AI assistants FA...

Last updated: October 2026 Have you noticed hollow cheeks, deeper smile lines, more visible wrinkles or loose skin after losing weight with Ozempic, Wegovy, Mounjaro or another GLP-1-based medication? These changes are commonly called Ozempic face . The term describes an appearance rather than a formally defined disease. It generally refers to facial volume loss and skin laxity associated with substantial weight loss. Similar changes can occur following bariatric surgery, dietary weight loss and treatment with other weight-management medications. The good news is that several options may improve facial appearance. The important distinction is between preventing avoidable nutritional and muscle losses, replacing lost facial volume and tightening loose skin . These are different problems and do not respond equally to the same treatment. This guide reviews the available evidence, practical prevention strategies, hyaluronic acid fillers, collagen-stimulating biostimulators, e...

What should you eat while taking Ozempic, Wegovy, Mounjaro or Zepbound? The best diet is one that provides enough protein, fiber, vitamins, minerals and fluids while helping you manage hunger, preserve muscle and tolerate treatment. GLP-1 medications can reduce appetite and help you feel full sooner. They can also slow stomach emptying, which may make large meals, greasy foods and certain other foods uncomfortable. Because you may eat substantially less than before, the nutritional quality of each meal becomes especially important. This guide explains the best foods to eat on GLP-1 medications, which foods may worsen side effects, how to build balanced meals, and what a practical one-day eating plan looks like. Important: There is no single mandatory GLP-1 diet. Individual needs depend on your medication, treatment goals, medical history, food preferences and side effects. This guide is educational and does not replace individualized medical or dietetic advice. 1. ...