One Day MD | Evidence-Based Wellness

Why do some people thrive on certain diets and supplements while others experience little benefit—or even side effects? The answer may lie partly in your genes. Advances in genetic testing, artificial intelligence, and personalized medicine have accelerated interest in the connection between genomics and supplements. This rapidly evolving field aims to tailor nutrition and supplementation based on an individual’s unique genetic makeup. Known as Nutrigenomics and Nutrigenetics, the science of gene-based nutrition is becoming one of the most discussed frontiers in health optimization, longevity, preventive medicine, and biohacking. In this guide, we explore: What genomics means in nutrition How genes affect supplement response The most important nutrient-related genes Evidence-based supplement personalization Risks and limitations Future trends in AI-powered precision nutrition What Is Genomics? Genomics is the study of the genome—the complete set of DNA instructions in the body. Genes i...

Nutrigenomics (also known as nutritional genomics) is broadly defined as the relationship between nutrients, diet, and gene expression [1]. In simple terms, nutrigenomics is the study of how genes and nutrients interact. Although it is an emerging science requiring more investigation and information, existing studies show that some people are more at risk than others for nutritional deficiencies because of their genetic makeup. The launch of the Human Genome Project in the 1990s and the subsequent mapping of human DNA sequencing ushered in the ‘era of big science’, jump-starting the field of nutrigenomics that we know today [2]. Although much of the early ‘hype’ around nutrigenomics has not yet come to fruition, the field remains nascent and fast-moving, with the potential to lay the foundations of truly ‘personalised nutrition’ approaches tailored to individuals [3]. It also poses both ethical and regulatory challenges. There is potential for personal data to be misused, in a...

Can diet, lifestyle and anti aging supplements reverse your age? This comprehensive guide examines the latest, scientifically-backed anti-aging supplements and methods, drawing on over 1,000 references and studies. By exploring both the biological hallmarks of aging and the most promising interventions, this article aims to provide readers with practical, evidence-based insights into how to support healthy aging and potentially extend lifespan. However, search engine results for "anti-aging" are largely dominated by skin care products and beauty guides. In reality, anti-aging science goes far beyond skin deep.  In This Article: Chapter 1: Methodology Chapter 2: What is Aging? Chapter 3: Biological Age vs Chronological Age Chapter 4: Causes of Aging and Hallmarks of Aging Chapter 5: What is Cell Senescence? Chapter 6: What is Epigenetics? Chapter 7:  Diet and Lifestyle for Anti Aging Avoid Sugar and Ultra-processed Foods Mediterranean Diet and Vegetables Avoid Smoking and Alc...