Medical Director

Our client is a well established Multi-National Corporation. They are looking for a professional with relevant experience in the pharmaceutical industry.


Do feel free to email your updated profile to us if you are keen to check out this new opportunity. In the event that you are not interested, appreciate if you can refer someone else to us.

Please email your updated CV to aih2020[at]gmail[dot]com.

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SELECT, STEP, SURPASS, SURMOUNT & FLOW: What the Landmark Semaglutide and Tirzepatide Trials Actually Prove (2026)

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By Dr. Frank Yap, MD  |  Medically reviewed by One Day MD Review Team  |  Last updated: August 2026 Quick Answer SELECT showed that semaglutide 2.4 mg cuts major cardiovascular events by 20% in people with overweight/obesity and existing heart disease who do not have diabetes. The STEP program (STEP 1–5, STEP 8, and the newer STEP UP trials) established semaglutide's weight-loss profile, with losses ranging from roughly 10% to over 20% of body weight depending on dose, population, and duration. The SURPASS program showed that tirzepatide — a dual GIP/GLP-1 agonist — produces larger HbA1c and weight reductions than semaglutide in type 2 diabetes, and the newly published SURPASS-CVOT (December 2025) confirmed tirzepatide is at least as cardioprotective as dulaglutide. FLOW showed semaglutide cuts major kidney disease events by 24% in people with type 2 diabetes and chronic kidney disease, which led the FDA to approve a dedicated kidney-protection indic...
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GLP-1 Drugs, Vitamin B1 and Wernicke Encephalopathy: What Happens When Weight Loss Goes Too Far?

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GLP-1 drugs can be highly effective for weight loss, but extreme appetite suppression, persistent nausea or vomiting, and very rapid weight loss can create a nutritional problem that is easy to overlook. One of the most serious possibilities is thiamine (vitamin B1) deficiency leading to Wernicke encephalopathy , a neurological emergency. Recent case reports, a 2025 pharmacovigilance analysis and a 2026 systematic review have raised a safety signal involving semaglutide, tirzepatide and other GLP-1-based therapies . The evidence remains limited and does not establish that GLP-1 drugs directly cause Wernicke encephalopathy in most users. Instead, the leading concern is an indirect pathway involving markedly reduced food intake, gastrointestinal intolerance, nutritional depletion and rapid weight loss . ( Gras et al., 2025 ; Goldman et al., 2026 ; Bidesie & Oudman, 2026 .) Key takeaway: The concern is not that everyone taking a GLP-1 medication ...
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Ivermectin for Parkinson’s and Dementia: Analyzing the Neuroprotective Molecular Evidence and Clinical Case Reports (2026)

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Scientific Review & Regulatory Audit by the Clinical Editorial Team The therapeutic paradigm for progressive neurodegenerative disorders like Parkinson’s disease (PD) and various forms of dementia faces a critical bottleneck. Standard pharmacology, primarily anchored by levodopa (L-DOPA) for Parkinson’s and acetylcholinesterase inhibitors for dementia, remains strictly symptomatic. These options frequently suffer from diminishing efficacy and significant side-effect profiles like L-DOPA-induced dyskinesia over long-term use. Consequently, the pharmaceutical community has focused heavily on drug repurposing—identifying established, safety-vetted compounds capable of crossing pathways to modify disease progression. An unexpected frontline candidate emerging in this space is ivermectin. Traditionally classified as a broad-spectrum antiparasitic agent, a surge of preclinical studies between 2020 and 2024 has unveiled its complex, multi-targeted pharmacodynamics within the mam...
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