The Elixir

Metformin and berberine both have potential for controlling blood sugar levels and problems related to them. While metformin is a prescription drug with a longer history of clinical usage, berberine is a naturally occurring substance that is accessible without a prescription. To make it easier for you to know the differences, here's a comparison of two: Source: Berberine: Berberine is a chemical found in some plants like European barberry, goldenseal, goldthread, Oregon grape, phellodendron, and tree turmeric. Metformin: Metformin is not derived from plants or animals. It is a synthetic pharmaceutical medicine, which means it was created in a laboratory rather than derived from nature. Metformin was developed using chemicals discovered in the French Lilac plant (Galega officinalis), however the medicine is manufactured using chemical processes. Medical Use: Berberine: Berberine has been used in traditional Chinese and Ayurvedic medicine for centuries. It has gained attention for it...

Why insulin resistance, visceral fat, and metabolic dysfunction quietly drive most modern illnesses — and what actually improves outcomes. This article is a core cluster within the Preventive Medicine & Longevity pillar on OneDayMD. It explains why metabolic health sits upstream of cancer, cardiovascular disease, dementia, kidney failure, and accelerated aging. Executive Overview Over the past 50 years, the global disease burden has shifted from infectious illness to chronic, lifestyle-associated disease . Despite appearing unrelated, most of these conditions share common biological roots: Insulin resistance Visceral adiposity Chronic low-grade inflammation Mitochondrial dysfunction Endothelial damage This article explains why metabolic dysfunction is not just a risk factor, but a unifying driver of modern disease — and why improving metabolic health consistently reduces mortality across populations. What Is Metabolic Health? Metabolic health refers to the body’s ability to: Mainta...

What actually reduces cancer risk — organ by organ — based on human evidence, not headlines or supplements. This guide is a core cluster article within OneDayMD’s Preventive Medicine & Longevity hub. It focuses on risk reduction , not guarantees, and prioritizes interventions supported by epidemiology and clinical data. AACR Cancer Progress Report 2023 / 2024 How to Read This Guide Cancer prevention is probabilistic. No intervention eliminates risk entirely. Each section highlights: 🟢 High-evidence risk reducers (consistent human data) 🟡 Moderate evidence factors (context-dependent) 🔴 Low or no evidence claims (common myths) Lung Cancer Prevention 🟢 High-Evidence Factors Smoking avoidance and cessation (dominant risk modifier) Avoidance of secondhand smoke Radon exposure mitigation Smoking cessation reduces lung cancer risk at any age , though risk never fully normalizes. 🟡 Moderate Evidence Air pollution reduction (population-level effect) Occupational exposure control (a...

An evidence-based guide to reducing chronic disease risk, extending healthspan, and understanding what truly works — beyond hype, supplements, and shortcuts. This page serves as the central hub for OneDayMD’s coverage of preventive medicine, cancer prevention, cardiometabolic health, and longevity science, grounded in epidemiology, clinical trials, and systems biology. What This Hub Covers (Quick Overview) This hub explains: What preventive medicine actually means in modern clinical science The difference between lifespan and healthspan Which interventions reduce disease risk with high-quality evidence Where longevity science is promising — and where it becomes speculation How lifestyle, medications, and emerging tools interact over decades It is designed for readers who want risk reduction, not biohacking fantasy . Executive Summary Preventive medicine focuses on reducing the probability of disease before it occurs , rather than treating pathology after it is established. Longevity ...

Controlled studies in people observed that vitamin K2 supplements generally improve bone and heart health, while vitamin K1 has no significant benefits for bone and heart health ( Source ). However, vitamin K2 is not available in plants. Sources:  X,com ,  X.com What is vitamin K and what does it do? Vitamin K is a nutrient that the body needs to stay healthy. It’s important for blood clotting and healthy bones and also has other functions in the body. If you are taking a blood thinner such as warfarin (Coumadin®), it’s very important to get about the same amount of vitamin K each day. How much vitamin K do I need? The amount of vitamin K you need depends on your age and sex. Average daily recommended amounts are listed below in micrograms (mcg). Life Stage Recommended Amount Birth to 6 months 2.0 mcg ...

Can diet, lifestyle and anti aging supplements reverse your age? This comprehensive guide examines the latest, scientifically-backed anti-aging supplements and methods, drawing on over 1,000 references and studies. By exploring both the biological hallmarks of aging and the most promising interventions, this article aims to provide readers with practical, evidence-based insights into how to support healthy aging and potentially extend lifespan. However, search engine results for "anti-aging" are largely dominated by skin care products and beauty guides. In reality, anti-aging science goes far beyond skin deep.  Conventional medicine focuses on treating the symptoms of injury, illness or disease. This passive system of treatment can extend lifespan but does not proactively improve health, leaving millions of people with a poor quality of life in their later years and the associated economic challenges they face.A proactive...