The Elixir

Repurposed drugs do not work in isolation. They work by modulating systems —metabolism, inflammation, immune signaling, mitochondrial function, and the tumor microenvironment. Systems medicine asks a different question than conventional care: Which measurable biological systems are drifting—and which interventions (lifestyle, metabolic, pharmacologic) shift them back toward resilience? That requires metrics, not narratives. The Systems Medicine Framework Systems medicine integrates three intervention layers , all guided by measurable biomarkers: Foundational physiology (metabolism, sleep, muscle, fitness) Targeted metabolic & immune modulation (nutrition, supplements, repurposed drugs) Conventional therapies when required Health metrics are the feedback loop that connects these layers. 1. Metabolic Metrics (Primary Targets of Many Repurposed Drugs) Insulin resistance is a shared vulnerability across cancer, neurodegeneration, cardiovascular disease, and aging. Key metrics: Fast...

You cannot improve what you cannot measure.  Tracking the right health metrics can predict disease risk years before symptoms appear. Instead of waiting for illness, modern preventive medicine focuses on measurable signals that reflect metabolic health, inflammation, cardiovascular fitness, and longevity. This guide breaks down the most important health metrics, explains why they matter, and shows optimal ranges backed by evidence—so you can make smarter, earlier health decisions. Why Health Metrics Matter More Than Diagnoses Traditional healthcare often reacts after disease develops . But chronic diseases like cancer, diabetes, heart disease, and neurodegeneration share early warning signs: Insulin resistance Chronic inflammation Loss of muscle mass Mitochondrial dysfunction Autonomic nervous system imbalance 👉 These changes are measurable years in advance . Tracking the right metrics shifts healthcare from reactive to preventive . 1. Core Vital Signs (Baseline Health Indicators...

Butyrate is a powerhouse short-chain fatty acid (SCFA) essential for gut integrity, immune balance, metabolism, and even brain health . This pillar page will guide readers through everything they need to know about butyrate — from supplements to foods, to strategies for boosting production naturally. Table of Contents What Is Butyrate? Best Butyrate Supplements Sodium & Calcium Butyrate Tributyrin Supplements Prebiotic + Butyrate Blends Clostridium butyricum Probiotics Best Foods That Increase Butyrate Naturally Resistant Starch Foods Soluble & Fermentable Fiber Polyphenol-Rich Foods Foods That Contain Butyrate Directly How to Maximise Butyrate Production Supplements vs Foods: Which Is Better? Who Benefits Most from Butyrate? Key Takeaways What Is Butyrate? Butyrate (butyric acid) is a short-chain fatty acid produced when beneficial gut bacteria ferment fiber and resistant starch. It is the main fuel for colon cells and regulates: Gut barrier integrity Immune system balance ...

For decades, longevity advice focused almost entirely on weight, BMI, and aerobic fitness . But a growing body of evidence now points to a far more powerful predictor of long-term health and survival: skeletal muscle mass and strength . Muscle is not just for movement or appearance. It is a metabolic, endocrine, and immune organ that plays a central role in glucose regulation, inflammation control, disease resilience, and functional independence. Losing muscle with age — a process known as sarcopenia — is strongly associated with frailty, chronic disease, hospitalization, and early mortality. In short: muscle is one of the most important assets you can build for a longer, healthier life. 1. Muscle Mass and Mortality: What the Evidence Shows Large population studies consistently show that people with higher relative muscle mass and strength live longer , regardless of body weight or fat mass. Key findings from epidemiologic and clinical research: Higher skeletal muscle mass is associa...

If you search online for stem cell supplements, you’re bound to find a long list. Figuring out what to make of all of these supplements can be pretty daunting, as each claims to be the best and greatest.  The Supplement Game  You need to be careful with supplements and health claims and especially stem cell supplements. Why? Generally, the process of creating a new supplement is pretty simple. You go online, find some studies that seem to fit what you’re looking for, create a master file, choose your ingredients, and you’re off. Meaning, no original lab or clinical research is performed. For example, to create a stem cell supplement, you could focus on the different ways that stem cells get impacted by supplement ingredients, like proliferation or stem cell production. This means that the substance helps stem cells make more of themselves. You then choose from some the ingredients below and you’ve got a new supplement. However, is this really what’s desired? Do you wa...

Magnesium is  one of the seven essential minerals we cannot live without . Magnesium is also a cofactor in more than 300 enzyme systems that regulate diverse biochemical reactions in the body, including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation ( NIH ). An essential dietary mineral, it is a required mineral co-factor in over 300 enzymes in the body. Since over 68% of Americans are magnesium deficient, this would be a good mineral to start consuming. Magnesium is also a component necessary for the activation of vitamin D , and without sufficient amounts of it, your body cannot properly utilize the vitamin D you’re taking.  Best Magnesium Supplements - Summary A. Magnesium L-Threonate Supplement – Memory, Focus & Overall Cognitive Performance Boost 1. Life Extension Neuro-Mag Magnesium L-Threonate B. Magnesium Glycinate Supplement – Helps with Sleep, Anxiety & ...