One Day MD | Evidence-Based Wellness

Quick Answer The best diet for dementia and Alzheimer’s disease is the MIND diet, followed closely by the Mediterranean diet. Supplements with the strongest supportive evidence include omega‑3 fatty acids (DHA/EPA), B‑vitamins (B6, B12, folate) for those with deficiency, vitamin D, and curcumin. No supplement or diet can cure Alzheimer’s, but metabolic and anti‑inflammatory nutrition patterns are associated with slower cognitive decline and reduced dementia risk. Why Diet and Supplements Matter in Dementia Alzheimer’s disease is increasingly recognized as a metabolic‑inflammatory neurodegenerative disorder , not just an amyloid condition. Key drivers include: Brain insulin resistance ("type 3 diabetes") Chronic neuroinflammation Oxidative stress and mitochondrial dysfunction Cerebrovascular impairment Diet and targeted supplementation influence all four pathways, making nutrition a foundational intervention for prevention and early‑stage support. Best Diets for Dementia and ...

Introduction NAD+ is one of the most important molecules for cellular energy, repair, and longevity. But there’s a lot of confusion about NAD+, NMN, NR, and liposomal supplements. In this guide, we’ll separate myths from science and show what actually works to support cellular health and healthy aging. Myth 1: You Can Take NAD+ Directly Many products claim to boost NAD+ by supplying NAD+ itself.  Reality: NAD+ is not orally bioavailable. Its large molecular size prevents it from entering cells intact. Oral NAD+ supplements are largely ineffective, so look for science-backed precursors like Niagen® (nicotinamide riboside) . Myth 2: NMN is More Effective than NR NMN (nicotinamide mononucleotide) must first convert into NR (nicotinamide riboside) outside the cell before being absorbed. This extra step makes NMN less efficient. NR, in the patented Niagen® form, enters cells directly and is clinically proven to increase NAD+ levels . Related: 10 Best NMN Supplements (2025 Review) Myth...

Aging shortens our lives through lifestyle and biological damage — but new longevity research suggests aging may be slowed and partially reversed. Here’s what science says. Can Aging Be Reversed — Or Are We Shortening Our Lives Without Realizing It? Modern science suggests that aging is not just the passage of time — it is a biological process driven by cumulative damage . Poor diet, sedentary behavior, chronic stress, sleep deprivation, and metabolic dysfunction all accelerate this damage, shortening both lifespan and healthspan. But there’s a shift underway. Researchers now believe aging may be modifiable , with growing evidence that targeted lifestyle changes and emerging medical interventions can slow aging — and potentially reverse certain biological markers of age . How We Shorten Our Lives (Often Without Knowing It) Many of the most powerful accelerators of aging are deeply embedded in modern life: 1. Chronic Inflammation Low-grade, long-term inflammation damages tissues, accele...

Exosomes are rapidly emerging as one of the most talked-about tools in regenerative aesthetics — often described as cell-free stem cell therapy. They are promoted for skin rejuvenation, post-procedure healing, hair restoration, and anti-aging. But separating scientific reality from marketing hype is essential. This pillar page serves as a central, authoritative hub on exosomes in aesthetics, integrating biology, clinical evidence, safety, regulation, and practical decision-making — with links to supporting articles across OneDayMD. In this Article: What Are Exosomes? How Exosomes Work in Regenerative Aesthetics Exosomes vs Other Regenerative Treatments Clinical Applications in Aesthetic Medicine Evidence Review: What Science Actually Supports Regulatory & Ethical Considerations Safety, Risks & Quality Control Exosomes in Longevity & Systems Medicine Future Directions in Regenerative Aesthetics Patient & Practitioner Decision Guide What Are Exosomes? Exosomes are nano-si...

In these past few years, stem cells, PRP (platelet-rich plasma) and exosomes have been hot topics among researchers and doctors. However, these forms of treatments are often mixed up and are confusing for most average consumers.  As of January 2026, there are  more than 300,000 studies  related to "stem cell",  more than 40,000 studies  published related to exosome and  more than 17,000 studies  related to PRP on PubMed (US NIH Library of Medicine Database).  Nevertheless, stem cell, PRP and exosome-related therapies are not yet established as standard treatments, given their relatively recent emergence. Regenerative medicine is also becoming a buzzword in the medical community. Why? Because the human body is specially equipped to heal itself, and regenerative therapies tap into this powerful ability. Regenerative medicine includes treatments like stem cell therapy, exosome therapy and platelet-rich plasma (PRP) therapy. Rese...

Regenerative biologics like exosomes , platelet-rich plasma (PRP) , and stem cells are increasingly discussed in aesthetic and regenerative medicine. But what are they , how are they different , and what does science actually support ? This guide breaks it down in clear, evidence-based terms. 1. What Are These Therapies? Exosomes Exosomes are tiny extracellular vesicles (≈30–150 nm) that cells naturally release to communicate with each other — carrying proteins, RNA, growth factors, and signaling molecules. They do not contain living cells or DNA , and instead act as biological messengers that influence neighboring cells. ( One Day MD ) Exosomes are studied for tissue repair, inflammatory modulation, and regenerative signaling — which is why they’re becoming popular in skin and hair aesthetics. Platelet-Rich Plasma (PRP) PRP is derived from a patient’s own blood. Blood is centrifuged to concentrate platelets, which release growth factors that can help support local tissue healing an...

An evidence-based guide to reducing chronic disease risk, extending healthspan, and understanding what truly works — beyond hype, supplements, and shortcuts. This page serves as the central hub for OneDayMD’s coverage of preventive medicine, cancer prevention, cardiometabolic health, and longevity science, grounded in epidemiology, clinical trials, and systems biology. What This Hub Covers (Quick Overview) This hub explains: What preventive medicine actually means in modern clinical science The difference between lifespan and healthspan Which interventions reduce disease risk with high-quality evidence Where longevity science is promising — and where it becomes speculation How lifestyle, medications, and emerging tools interact over decades It is designed for readers who want risk reduction, not biohacking fantasy . Executive Summary Preventive medicine focuses on reducing the probability of disease before it occurs , rather than treating pathology after it is established. Longevity ...