Vitamin D, Hydroxychloroquine and Pancreatic Cancer - Dr Stephen Bigelsen

Pancreatic cancer, which affects about 60,000 Americans every year, is one of the deadliest forms of cancer. After diagnosis, fewer than 10 percent of patients survive for five years.

While some chemotherapies are initially effective, pancreatic tumors often become resistant to them. The disease has also proven difficult to treat with newer approaches such as immunotherapy.

Pancreatic Cancer and CA19-9 Tumor Marker Levels

The graph below displays the test results of a Stage 4 Pancreatic Cancer patient's tumor marker levels over time.  

The lower the CA19-9, in general, the lower the cancer activity. Within days of adding a repurposed drug cocktail to standard treatment, this patient’s CA19-9 level dropped like a stone, faster than any of his Oncologists had seen with this type of cancer. The repurposed drugs he added were Hydroxychloroquine and Paricalcitol - a form of injectable Vitamin D.

A normal CA19-9 level in someone without cancer is below 35. This patient with terminal Pancreatic cancer saw his levels drop from 11,500 to below 35 in about three months. However, he was not an average patient; he was himself a physician.

Dr. Stephen Bigelsen has taught at Rutgers University Medical School as a professor in Allergy and Immunology. He is a scientist and goes by the book. He researched his cancer and spoke to others who did more specific research, and he did not accept the consensus standard of care. Instead, he innovated, and he remains alive, some five years later, fully recovered from Pancreatic Cancer. Like Ivermectin, Hydroxychloroquine and Paricalcitol are repurposed drugs. They are deemed safe and effective by the FDA for another disease, yet used in cancer after showing scientific promise.

Like Ivermectin, the FDA and regulators hate the idea of repurposed drugs because they are being used without their permission or approval. Regardless, it is legal for physicians to prescribe them if they believe, based upon their knowledge and experience, it may help or even save a life. In the case of Dr. Bigelsen, it was his own life that was saved.

About Dr Stephen Bigelsen

Department of Allergy, Asthma and Immunology, Rutgers New Jersey Medical School, Newark, NJ, USA, ten.enilnotpo@gibrns
Correspondence: Stephen Bigelsen, Department of Allergy, Asthma and Immunology, Rutgers New Jersey Medical School, 57 Melrose Road, Mountain Lakes, NJ 07046, USA, 
Tel +1 973 989 0500, 
Email: ten.enilnotpo@gibrns


#1. Suppose no one survives Stage 4 Pancreatic Cancer using standard treatment - the standard treatment of chemo/radiation/surgery received by Alex Trebek, Patrick Swayze, and Michael Landon. Why don't we INFORM ALL cancer patients that repurposed drugs are an option? Must you be a physician like Dr. Stephen Bigelsen to get the repurposed cocktail? Most of us would never know even to ask.

Must a patient stumble on a book that explains this?

Very few people stumble upon repurposed drugs for cancer. As a result, 99.999% never get the type of treatment that Dr. Bigelsen did. And he tells his story that getting into a clinical trial is not all that helpful if you get only one drug, or only get the placebo, or if you wait until the late stages when cancer has returned in a resistant state.

Getting into a clinical trial after all else fails in cancer care is too little, too late. It may help the study, but it usually does little for the patient. Dr. Bigelsen got all the drugs started by writing a prescription for himself, something most of us cannot do.

The repurposed drug cocktails MUST BE STARTED EARLY.

It is the same with COVID-19. The earlier one starts the Ivermectin, the better. In India, entire households would begin the Ivermectin the moment one family member got sick. This strategy proved remarkably effective, and it did not produce deaths, strokes, or blood clots.

What is the point of all this? 1.9 million Americans contract cancer each year, and 600,000 die from the disease. These numbers, in my opinion, can be reduced by 1/3 by the widespread adoption of repurposed drug cocktails. Unfortunately, the standard of care for most cancers remains Chemo/Radiation/Surgery. I write a lot about the SAM cocktail, a combination of Statin/Aspirin/Metformin. Dr. Bigelsen writes about this as well.


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