7 Best Nitric Oxide Supplements Review 2024

One of the most popular supplements nowadays is one that increases nitric oxide in the body. These supplements do not include nitric oxide itself, they contain compounds that your body can use to produce nitric oxide. 

Nitric oxide is a widespread signaling molecule that is involved in almost every cellular and organ function in the body. Nitric Oxide is one of the most important molecules for blood vessel health!

Benefits of Taking Nitric Oxide Supplements

A. Lower Blood Pressure

Hypertension is a key risk factor for cardiovascular disease because it damages arteries by making them less elastic, reducing blood and oxygen flow to the heart and leading to heart disease. Additionally, lowering high blood pressure lowers the risk of cardiovascular events.

Nitric Oxide is a vasodilator, which means it relaxes the inner muscles of your blood vessels, widening them. Nitric oxide enhances blood flow and decreases blood pressure in this way.

A study showed that nitric oxide supplementation appears to lower blood pressure in patients with prehypertension and might be beneficial as a routine supplementation for cardiovascular protection.

B. Help Treat Erectile Dysfunction

Erectile dysfunction is the inability to achieve and maintain an erection suitable for sexual intercourse.

Nitric oxide activates relaxation of corporal cavernosal smooth muscle tissue allowing more blood to flow into the penis, resulting in an erection. Several supplements, including L-citrulline, L-arginine and French maritime pine bark extract, have been proven to enhance nitric oxide levels in men with erectile dysfunction.

C. Muscle Soreness May Be Reduced

In one study was determine the effects of a single dose of citrulline malate (CM) on the performance of flat barbell bench presses as an anaerobic exercise and in terms of decreasing muscle soreness after exercise.

Those given citrulline malate had 40% less muscle soreness 24 and 48 hours after the exercise than those given a placebo.

D. May Be Beneficial for Type 2 Diabetes

In persons with type 2 diabetes, nitric oxide production is reduced. This results in poor blood vessel health, which can eventually lead to high blood pressure, kidney illness, and heart disease.

As a result, nitric oxide-increasing supplements may have important implications for diabetes therapy and disease prevention.

Best Nitric Oxide Supplements

1. SILVERONYX Extra Strength Nitric Oxide Supplement L Arginine 3X Strength

SILVERONYX Extra Strength Nitric Oxide Supplement L Arginine 3X Strength

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Best nitric oxide supplements for working out

– Extra Strength Nitric Oxide:
Our premium nitric oxide supplements stack includes: L Arginine, Niacin, Calcium, L Arginine Akg 2:1 Extract, L Citrulline, Malate Extract and Beta Alanine; These extra strength ingredients provide for supercharged muscle pumps

– Supports Muscle Growth and Recovery:
SilverOnyx Nitric Oxide supplements for men are specially formulated with L Citrulline and L Arginine for help support muscle growth and recovery from normal workout routines

– Increased Workout Production:
Nitric Oxide helps support workouts from pre-workout prep to providing a powerful ‘pump’ to quick recovery

– For Everyone:
SilverOnyx Nitric Oxide capsules are natural formulas optimized for women and men of all ages

– Bottled in the USA:
Each bottle of our Nitric Oxide Arginine Supplement is proudly formulated and bottled in the USA following strict cGMP guidelines; Reviewed by third party lab for quality and purity

4.3 out of 5 – more than 7,800 global ratings

SILVERONYX Extra Strength Nitric Oxide Supplement Reviews
Nitric oxide is made in the body when we exercise. Is is a vasodialator which expands blood vessels naturally and increases blood flow. This product helped me to get in shape enough to exercise and began making my own naturally.

2. N.O. XT Nitric Oxide Supplement with Nitrosigine L Arginine & L Citrulline

N.O. XT Nitric Oxide Supplement with Nitrosigine L Arginine & L Citrulline

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Best nitric oxide supplements for blood flow

– Elite Nitric Oxide Booster:
Power through your workouts with skin-tearing pumps, endless endurance, and increased strength. N.O. XT is scientifically formulated using cutting-edge ingredients that help boost nitric oxide and enhance blood flow to the muscles during training. Improved blood flow allows for greater nutrient delivery and muscle fullness.

– Boosts Energy, Muscle Growth and Recovery:
Nitric oxide is important for relaxing and expanding blood vessels while you train. Boosting nitric oxide helps fuel nutrient delivery to working muscle tissue, creating an optimal anabolic environment for muscle building. The increased blood flow will enhance your pumps, strength, and endurance in the gym.

– Increases Pre Workout Efficiency:
Jacked Factory’s nitric oxide booster push your exercise to a new level. The strong combination of the L-Arginine, L Citrulline and Nitrosigine work synergistically to increase nitric oxide production, bring you strong muscular pumps and endurance, and delay fatigue in the gym.

– Manufactured in a USA cGMP Facility:
All Jacked Factory supplements are manufactured in a state-of-the-art cGMP facility. We strive to challenge the status quo by delivering the highest standards in quality.

4.3 out of 5 – more than 12,200 global ratings

N.O. XT Nitric Oxide Supplement Reviews
I’ve been taking the recommended daily dosage of N.O. XT Nitric Oxide with a multi-vitamin and a very low dosage of Lisinopril for controlling high blood pressure, and have not experienced any adverse side effects, not even bad breath. I tried several other brands of L-Arginine and Nitric Oxide boosters and supplements that made all sorts of claims, but they did not work as advertised, and many gave me stomach cramps. Jacked Facory’s N.O. XT Nitric Oxide is easy to swallow, and I can feel the effects within an hour of ingesting it. Since I started taking N.O. XT Nitric Oxide, I feel more energized and less fatigued, and my workouts are more intense. I plan to purchase another bottle soon.

3. Nature's Pure Blend : Nitric Oxide Supplements

Nitric Oxide Supplements: Nature's Pure Blend

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Best nitric oxide supplements for high blood pressure

Nitric Oxide is naturally produced by your body. Almost every single cell in your body produces Nitric Oxide. Nitric Oxide is a vasodilator, which means it dilates and relaxes the inner muscles of blood vessels. This causes your blood vessels to widen and relax which in effect increases blood flow and supports normal blood pressure levels.

– All Natural Ingredients:
At Natures Pure Blend, we strive to live up to our name. With our supplements, you’ll always find 100% natural ingredients, which included science-based clinically effective dosages. We hold ourselves to the highest standard of quality and integrity and have committed to NEVER using artificial sweeteners, food dyes, or harmful additives.

4.4 out of 5 – more than 1,900 global ratings

Nitric Oxide Supplements: Nature’s Pure Blend Reviews
If you’re looking for a vasodilator, this product is for you. It increases blood flow without giving a tingling sensation like other supplements, such as C4. The capsules are filled consistently, and there are no strange flavors or smells. Shipping was fast. I’m very happy with this product.

4. Vatellia Life High-Absorption Nitric Oxide

Vatellia Life High-Absorption Nitric Oxide

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Best nitric oxide supplements for heart health

Nitric oxide has many natural healing properties and plays a role in regulating blood pressure and the rest of the cardiovascular system. Helps to create a healthy cardiovascular system by supporting the production of nitric oxide, the molecule responsible for relaxing blood vessels and maintaining normal blood pressure and blood flow.

Nitric Boost provides your endothelial cells the nutrients they need to make nitric oxide. Nitric Boost can help you improve your workout performance and give you the endurance you need to achieve better results. Better blood flow to your muscles allows you to go harder, longer. Nitric Boost provides both men and women with increased physical endurance, better post-workout muscle recovery (anti-inflammatory support) and overall improved blood circulation.

Vatellia Life High-Absorption Nitric Oxide Reviews
I’ve been taking Nitric Boost the past 6 months as part of my plan to get off Lisinopril for my high blood pressure. I’m worried about kidney damage from long term use of blood pressure drugs.

I love that the bottle has a two month supply so I don’t have to remember to order every month. PIMA.

Not sure if my blood pressure has come down because I don’t trust the drug store blood pressure cuffs. I feel good though. We’ll see what the doctor says at my next visit. Keep your fingers crossed for me!

5. Fuel by Toniiq Nitric Oxide Booster

Fuel by Toniiq Nitric Oxide Booster

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– High Purity Clinically Proven Ingredients:
Toniiq Fuel has been engineered as the ultimate Nitric Oxide supplement. Our 3,000mg formula was produced with the very latest in fermentation technology, and contains a highly purified patented blend of L-Arginine and L-Citruline, along with our own super-concentrated Beet Root extract.

– Patented Performance Blend:

VELOX is a clinically studied blend of L-Citrulline and L-Arginine that has been shown to boost Nitric Oxide levels more rapidly than L-Arginine alone.* Patented to rapidly increases blood Arginine levels, VELOX has been shown to increase power output, reduce muscle soreness, and synergistically increase blood Arginine levels.*

– Best L-Arginine and L-Citrulline Supplements:
To ensure that you are getting the highest-quality l arginine and l citrulline product, each batch is tested for quality and purity both during and after manufacturing.

– Quality, First, and Foremost:
Toniiq products are produced in a GMP-certified and NSF-approved state-of-the-art manufacturing facility right here in the USA.

– Each Batch is Individually Tested:
We test each batch both ourselves and through a third-party independent laboratory to ensure our ingredients contain the correct standardized level of purity and active ingredients. We also test each batch for any possible additives, contaminants, and impurities to ensure the highest level of quality.

4.2 out of 5 – more than 550 global ratings

Fuel by Toniiq Nitric Oxide Booster Reviews
All I can say is wow… It’s like having the fountain of youth in a bottle!!! This product is amazing felt endurance stamina and also seen the production of Lean muscle mass also felt relief in tendons and ligaments allowing me to push harder in the gym and see more productive Gains…

6. Havasu Nutrition L Arginine Male Enhancing Supplement From Nitric Oxide

Havasu Nutrition L Arginine Male Enhancing Supplement From Nitric Oxide

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L-arginine is an essential amino acid that the body needs to function properly. Like other amino acids, l-arginine plays a role in building protein. A boost in protein synthesis can help to improve lean muscle mass, endurance and performance. Be a man & take l arginine supplements!

In addition to muscle growth, l-arginine helps to release nitric oxide in the blood. This no booster acts to widen blood vessels in the blood stream, aiding in certain circulatory conditions. We’ve heard from several of our customers that this increase in circulation helps to enhance other areas of their life too.

– it has been proven that adding beet root with l-arginine and l-citruline, you can increase the levels of nitric oxide even more.

– the nitric oxide boost (no) is important for p function because it helps blood vessels relax, so more oxygen-rich blood can circulate through your arteries. Healthy blood flow to the arteries of the area below is essential for normal function.


4.2 out of 5 – more than 41,100 global ratings

Havasu Nutrition L Arginine Male Enhancing Supplement From Nitric Oxide Reviews
Being a college student, I have accumulated tons of stress and lack sleep. Havasu’s L-Arginine does not compare to other brands on the shelf. This product has noticeably balanced my hormone levels and has given me a natural, much-needed boost of energy. I sale results within the first 2 weeks of use. I highly recommend users to at least give this product a try and you will be pleasantly surprised!

7. BioNox Nutrients Nitric Oxide Blood Pressure Arginine Supplement

BioNox Nutrients Nitric Oxide Blood Pressure Arginine Supplement

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Created by doctors & uses the correct ratio of l-arginine & l-citrulline for your benefit, m3 has been reviewed by a team of medical professionals and it is: safe – effective – properly dosed for benefit claims – pharmacokinetically evaluated and has clinical history in high blood pressure support. It uses the highest ratio of arginine to citrulline available as shown in many studies to be the most effective.

pH balance & absorbtion your body produces n.O. In an alkaline environment. We’ve added deep ocean minerals to balance your ph. Minerals also help with absorption. Astragin is a proprietary blend of herbs specifically formulated to help you absorb up to 60% more of the nutrients in m3.

4.5 out of 5 – more than 800 global ratings

BioNox Nutrients Nitric Oxide Blood Pressure Arginine Supplement Reviews
This product has so many great reviews but I have no idea if it’s working for me. I have been taking it for months but I do not notice any changes – increase in energy or change in aches or pains. Maybe my blood pressure will be lower in my next physical. I will continue to take this product and hope I see the results that others are seeing. As for value for money, I am not sure if product is affecting my blood vessels etc.

During my physical, I learned that my blood pressure was high. I took this product religiously everyday for two weeks. Today, my blood pressure was normal! I also have less aches and pains. I’ve stocked up.

Other Strategies to Restore Nitric Oxide Production

  • Healthy balanced diet with lots of green vegetables.
  • Moderate physical exercise.
  • Infrared light therapy or infrared sauna.

Things that Disrupt Nitric Oxide Production

  • High carbohydrate and highly processed junk food. High glucose causes glycation of the enzyme that makes nitric oxide.
  • Antiseptic mouthwash, fluoride, antacids and proton pump inhibitors (PPIs).

Nitric Oxide Product Categories

  • L-Arginine and L-Citrulline supplements: If you are eating a healthy diet, you may not be deficient in these amino acids. Do not take more than the recommended dosage.
  • Beet root based products: Most of them do not contain sufficient nitrate or nitrite to cause any significant changes in nitric oxide production.


a. Nitric Oxide Side Effects

Nitric oxide might have certain un-favorable side effects in addition to its beneficial ones. Although not all of these side effects are likely to occur, if they do, medical treatment may be required.

If you experience any of the following negative effects while taking nitric oxide, contact your doctor or nurse immediately.

More common:
- blurred vision
- confusion
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- sweating
- unusual tiredness or weakness

Incidence not known:
- bluish lips or skin
- chest discomfort
- difficult or labored breathing
- dizziness
- tightness in the chest
- trouble breathing

Get emergency help immediately if any of the following symptoms of overdose occur while taking nitric oxide:

Symptoms of overdose
- bluish-colored lips, fingernails, or palms
- dark urine
- fever
- headache
- pale skin
- rapid heart rate
- sore throat
- unusual bleeding or bruising

b. What Are the Symptoms of Low Nitric Oxide?

High blood pressure, memory problems, low stamina, and erectile dysfunction are all symptoms of low nitric oxide levels. However, cigarette smoking, a high-fat, high-cholesterol diet, and little to no exercise are all potential contributors to these symptoms.

c. Who Shouldn’t Take Nitric Oxide Supplements?

Anyone with low blood pressure should avoid taking nitric oxide supplements since their blood pressure may drop even worse. Nitric oxide supplements should be avoided by those with cirrhosis since they can injure the liver even more. Guanidinoacetate methyltransferase deficiency is an uncommon disorder in which persons lack the enzyme that converts arginine to creatine. Nitric oxide supplements should be avoided by anyone who have this problem.

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