Best Nitric Oxide Supplements for Blood Pressure 2023

One of the most popular supplements nowadays is one that increases nitric oxide in the body. These supplements do not include nitric oxide itself, they contain compounds that your body can use to produce nitric oxide.

Nitric oxide is a widespread signaling molecule that is involved in almost every cellular and organ function in the body. It is one of the most important molecules for blood vessel health!

Does Nitric Oxide Lower Blood Pressure?

Yes! Nitric Oxide is a vasodilator, which means it relaxes the inner muscles of your blood vessels, widening them. Nitric oxide enhances blood flow and decreases blood pressure in this way.

A study showed that nitric oxide supplementation appears to lower blood pressure in patients with prehypertension and might be beneficial as a routine supplementation for cardiovascular protection.

How Fast Does Nitric Oxide Lower BP?

A blinded placebo-controlled crossover study evaluated the acute effects of an orally disintegrating lozenge that generates nitric oxide (NO) in unmedicated hypertensive patients. NO supplementation resulted in a significant reduction in diastolic blood pressure at 20 minutes and a significant reduction in systolic and diastolic blood pressure after 60 minutes.

Can You Take Nitric Oxide With Blood Pressure Medication?

The supplements may also interfere with diabetes and high blood pressure medications. Anyone considering using nitric oxide supplements should consult their doctor first to ensure that they will not interact with any existing conditions or medications.

Best Nitric Oxide Supplements for Blood Pressure

1. Neo40 Professional - Nitric Oxide Booster with Methylfolate

Neo40 Professional - Nitric Oxide Booster with Methylfolate

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Natural Blood Pressure Supplement

– Increase Nitric Oxide Production:
Neo40 Professional is a quick dissolve tablet which works quickly to help increase your body’s Nitric Oxide.

– Clinically Tested and Patented:
Created by HumanN based on exclusive patents licensed from the University of Texas Health Science Center. We are the only company that holds an exclusive license to use our patented N-O platform technology

– Helps Promote Cardiovascular and Healthy Blood Pressure:
Neo40 Professional helps support healthy blood pressure levels already in the normal range

– Great Tasting Quick Dissolve Tablets:
Neo40 Professional has a great taste and dissolves quickly in the mouth

4.5 out of 5 – more than 900 global ratings

Neo40 Professional – Nitric Oxide Booster with Methylfolate Reviews
Blood Pressure average before Neo40.. 158/95..on 12.5 mg Lisinopril
After taking Neo40..1 in the morning as soon as I wake up..
Blood Pressure med at 12:00..
and another Neo40 between 6 & 8
Blood pressure average is 118/72 consistently for over a month
Worth the Price!

2. N.O. XT Nitric Oxide Supplement with Nitrosigine L Arginine & L Citrulline

N.O. XT Nitric Oxide Supplement with Nitrosigine L Arginine & L Citrulline

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– Elite Nitric Oxide Booster:
Power through your workouts with skin-tearing pumps, endless endurance, and increased strength. N.O. XT is scientifically formulated using cutting-edge ingredients that help boost nitric oxide and enhance blood flow to the muscles during training. Improved blood flow allows for greater nutrient delivery and muscle fullness.

– Boosts Energy, Muscle Growth, and Recovery:
Nitric oxide is important for relaxing and expanding blood vessels while you train. Boosting nitric oxide helps fuel nutrient delivery to working muscle tissue, creating an optimal anabolic environment for muscle building. The increased blood flow will enhance your pumps, strength, and endurance in the gym.

– Increases Pre Workout Efficiency:
Jacked Factory’s nitric oxide booster push your exercise to a new level. The strong combination of the L-Arginine, L Citrulline and Nitrosigine work synergistically to increase nitric oxide production, bring you strong muscular pumps and endurance, and delay fatigue in the gym.

– Manufactured in a USA cGMP Facility:
All Jacked Factory supplements are manufactured in a state-of-the-art cGMP facility. We strive to challenge the status quo by delivering the highest standards in quality.

4.3 out of 5 – more than 12,200 global ratings

N.O. XT Nitric Oxide Supplement Reviews
I’m likely a bit different than their usual customer. I do workout & stay fit, but I started taking this on the advice of a physician for my blood pressure. It has been amazing at lowering my blood pressure and even allowed me to decrease some of the prescription medication I take!! What a great product! I love it? Thank you!

3. Nitric Oxide Supplements: Nature's Pure Blend

Nitric Oxide Supplements: Nature's Pure Blend

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Nitric Oxide is naturally produced by your body. Almost every single cell in your body produces Nitric Oxide. Nitric Oxide is a vasodilator, which means it dilates and relaxes the inner muscles of blood vessels. This causes your blood vessels to widen and relax which in effect increases blood flow and supports normal blood pressure levels.

– All Natural Ingredients:
At Natures Pure Blend, we strive to live up to our name. With our supplements, you’ll always find 100% natural ingredients, which included science-based clinically effective dosages. We hold ourselves to the highest standard of quality and integrity and have committed to NEVER using artificial sweeteners, food dyes, or harmful additives.

4.4 out of 5 – more than 1,900 global ratings

Nitric Oxide Supplements: Nature’s Pure Blend Reviews
Received my nitric oxide a few days back! Amazing !! I use it as a preworkout right before I work out and have amazing energy, pumps and blood flow at the gym! Also, my end of day blood pressure was amazing!! …This nitric oxide truly works for improved circulation no doubt! I highly recommend this product and will definitely keep buying!

4. Vatellia Life High-Absorption Nitric Oxide

Vatellia Life High-Absorption Nitric Oxide

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Best Nitric Oxide Supplements for Heart Health

Nitric oxide has many natural healing properties and plays a role in regulating blood pressure and the rest of the cardiovascular system. Helps to create a healthy cardiovascular system by supporting the production of nitric oxide, the molecule responsible for relaxing blood vessels and maintaining normal blood pressure and blood flow.

Nitric Boost provides your endothelial cells the nutrients they need to make nitric oxide. Nitric Boost can help you improve your workout performance and give you the endurance you need to achieve better results. Better blood flow to your muscles allows you to go harder, longer. Nitric Boost provides both men and women with increased physical endurance, better post-workout muscle recovery (anti-inflammatory support) and overall improved blood circulation.

Vatellia Life High-Absorption Nitric Oxide Reviews
I’ve been taking Nitric Boost the past 6 months as part of my plan to get off Lisinopril for my high blood pressure. I’m worried about kidney damage from long term use of blood pressure drugs.

I love that the bottle has a two month supply so I don’t have to remember to order every month. PIMA.

Not sure if my blood pressure has come down because I don’t trust the drug store blood pressure cuffs. I feel good though. We’ll see what the doctor says at my next visit. Keep your fingers crossed for me!

5. BioNox Nutrients Nitric Oxide Blood Pressure Arginine Supplement

BioNox Nutrients Nitric Oxide Blood Pressure Arginine Supplement

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Created by doctors & uses the correct ratio of l-arginine & l-citrulline for your benefit, m3 has been reviewed by a team of medical professionals and it is: safe – effective – properly dosed for benefit claims – pharmacokinetically evaluated, and has a clinical history in high blood pressure support. 

Moreover, we’ve added deep ocean minerals to balance your ph. Minerals also help with absorption. Astragin is a proprietary blend of herbs specifically formulated to help you absorb up to 60% more of the nutrients in M3.

4.5 out of 5 – more than 800 global ratings

BioNox Nutrients Nitric Oxide Blood Pressure Arginine Supplement Reviews
This product has so many great reviews but I have no idea if it’s working for me. I have been taking it for months but I do not notice any changes – increase in energy or change in aches or pains. Maybe my blood pressure will be lower in my next physical. I will continue to take this product and hope I see the results that others are seeing. As for value for money, I am not sure if product is affecting my blood vessels etc.

During my physical, I learned that my blood pressure was high. I took this product religiously everyday for two weeks. Today, my blood pressure was normal! I also have less aches and pains. I’ve stocked up.

6. Nutricost Nitric Oxide Booster 750mg, 180 Capsules

Nutricost Nitric Oxide Booster 750mg, 180 Capsules

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Nutricost’s Nitric Oxide Booster has 500mg of L-Arginine, 500mg of L-Arginine HCl, 500mg of Arginine AKG 2:1, 375mg of L-Citrulline, and 375mg of L-Citrulline Malate 2:1 in every serving. Each bottle contains 180 capsules and 60 servings.

If taken according to recommended use, one bottle is a 2 month supply. These Nitric Oxide Booster capsules are non-GMO, gluten free, and tested by independent ISO accredited laboratories.

Nutricost Nitric Oxide Booster for Blood Pressure Reviews
I like the product and recommend it
Some take it for other reasons but its use is to open up blood vessels and allow increased blood flow more energy lowering Blood Pressure


a. Nitric Oxide Side Effects

Nitric oxide might have certain unfavorable side effects in addition to its beneficial ones. Although not all of these side effects are likely to occur, if they do, medical treatment may be required.

If you experience any of the following negative effects while taking nitric oxide, contact your doctor or nurse immediately.

More common
- blurred vision
- confusion
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- unusual tiredness or weakness

Incidence not known
- bluish lips or skin
- chest discomfort
- difficult or labored breathing
- dizziness
- tightness in the chest
- trouble breathing

Get emergency help immediately if any of the following symptoms of overdose occur while taking nitric oxide:

Symptoms of overdose
- bluish-colored lips, fingernails, or palms
- dark urine
- fever
- headache
- pale skin
- rapid heart rate
- sore throat
- unusual bleeding or bruising

b. What Are the Symptoms of Low Nitric Oxide?

High blood pressure, memory problems, low stamina, and erectile dysfunction are all symptoms of low nitric oxide levels. However, cigarette smoking, a high-fat, high-cholesterol diet, and little to no exercise are all potential contributors to these symptoms.

c. Who Shouldn’t Take Nitric Oxide Supplements?

Anyone with low blood pressure should avoid taking nitric oxide supplements since their blood pressure may drop even worse. Nitric oxide supplements should be avoided by those with cirrhosis since they can injure the liver even more. Guanidinoacetate methyltransferase deficiency is an uncommon disorder in which persons lack the enzyme that converts arginine to creatine. Nitric oxide supplements should be avoided by anyone who have this problem.

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