10 Best Supplements for Histamine Intolerance 2022

Histamine is a significant chemical that is involved in numerous body functions. It stimulates gastric acid secretion, contributes to inflammation, dilates blood vessels, etc. However, too much histamine can be problematic, causing histamine sensitivity or intolerance, digestive issues, allergies, and more.

If you suspect a histamine intolerance, you should avoid alcohol and histamine-rich foods. Moreover, you can take antihistamines for combatting the symptoms for a short period of time.

Histamine Intolerance Symptoms

Common symptoms of histamine intolerance:
headaches or migraines
nasal congestion or sinus issues
fatigue
hives
digestive problems, such as diarrhea
irregular menstrual cycle
nausea
vomiting

Symptom severity varies from person to person.
People who have both allergies and a histamine intolerance may experience more severe allergic reactions because histamine levels in the body might accumulate. These can include asthma episodes or even anaphylactic shock, a serious, fast reaction that results in breathing difficulties and a drop in blood pressure that poses a life-threatening risk.

High amounts of histamine may be linked to significant chronic diseases like Crohn’s disease and can cause the heart to beat irregularly.

Best Supplements for Histamine Intolerance

A. Probiotic for Histamine Intolerance
1. Low Histamine Probiotics by VitaMonk™
2. Lifted Naturals Probiotics Histamine Free
3. Kyolic Kyo-Dophilus Multi 9 Probiotic for Strong Gut

B. Diamine Oxidase Supplement for Histamine Intolerance
4. Bravado Labs DAO Enzyme Supplement for Food-Derived Histamine Intolerance
5. Omne Diem DAO Histamine Neutralizing Enzyme
6. NaturDAO Diamine Oxidase Enzyme Supplement Histamine Blocker

C. Vitamin C, Stinging Nettle, Quercetin, Bromelain
7. ForestLeaf Quercetin with Bromelain, Vitamin C and Stinging Nettle
8. Solaray Quercetin & Bromelain + Vitamin C
9. NOW Supplements, Respir-All™ with Quercetin, Vitamin C, Nettle Extract and Bromelain
10. Nature Sunshines Histamine Block

A. Probiotic for Histamine Intolerance

Probiotic benefits

Many people take probiotics for histamine intolerance in an effort to restore gut bacterial balance. Probiotics may enhance gut bacterial populations and enhance overall health, according to numerous research. This is a fantastic solution overall.

Some probiotic strains, however, create histamine, which might worsen the symptoms. Therefore, always look for probiotics that are low in histamine.

Which Probiotics for Histamine Intolerance?

​Low histamine probiotics and strains to look for:
– Bifidobacterium infantis
– Lactobacillus gasseri
– Bifidobacterium breve
– Bifidobacterium bifidum
– Lactobacillus salivarius
– Lactobacillus rhamnosus (especially GG)
– Bifidobacterium longum
– Bifidobacterium lactis
– Lactobacillus plantarum

Which Probiotics to Avoid With Histamine Intolerance?

These species could either boost your body’s natural production of histamine or actually contain it, so you must avoid:
– Lactobacillus casei
– Lactobacillus Bulgaricus
– Streptococcus thermophilus
– Lactobacillus delbrueckii
– Lactobacillus helveticus

1. Low Histamine Probiotics by VitaMonk™

Low Histamine Probiotics by VitaMonk™

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– Low Histamine Probiotic Supplement
Many probiotics can actually cause your symptoms, our low histamine probiotic supplement contains 45 BILLION units of histamine blocking probiotic strains clinically shown to restore histamine balance already within normal ranges. Note: some questions about brown or black specs in the capsules. This is 100% normal. Saccharomyces boulardii will normally look like black specs in the capsules.

– Strongest Formula
Our histamine intolerance probiotic is 3-5x stronger than most competitors. 8 different strains and 45 billion units keep your gut soothed, immune system strong (already within normal ranges), and mind balanced.

– No Side Effects
100% all-natural. That means no additives, synthetics, or fillers that cause even worse symptoms than they’re designed to block. If you’re seeking health improvements but have a particularly sensitive stomach, these soothing low histamine probiotics are for you.

Ratings
4.4 out of 5 – more than 400 global ratings

Low Histamine Probiotics by VitaMonk™ Reviews
I have been experimenting with various probiotics to help with histamine intolerance and this is the best I’ve found so far. Some other probiotics have actually made it worse. My main symptoms are congestion after eating, arrythmias, itching, flushing, anxiety, and insomnia. This probiotic has helped with all of those. If I don’t take it, I wake up in the middle of the night and have trouble falling back asleep.

Digestive issues were not a big problem for me, but this brand helps keep me regular, unlike other probiotics, which made me go to one extreme or the other. I also follow a low histamine diet and take a DAO enzyme supplement with dinner. This probiotic lets me be a little less restrictive about what I eat.

2. Lifted Naturals Probiotics Histamine Free

Lifted Naturals Probiotics Histamine Free

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Bifidus Mood Boost Probiotic is our Bifidus-Only MOOD formulated probiotic featuring 4 feel-good strains of probiotic bacteria + prebiotic GOS; all designed to help with mood health, digestive health, and immune health.⁠

Probiotic Blend: Bifidobacterium infantis, Bifidobacterium breve, Bifidobacterium bifidum, Bifidobacterium longum.

Lifted Naturals Probiotics Histamine Free Reviews
Great product for people suffering with histamine intolerance as I couldn’t tolerate any other probiotic I noticed a difference after I started taking these. My symptoms started to improve and I feel better. I will continue to purchase this

3. Kyolic Kyo-Dophilus Multi 9 Probiotic for Strong Gut

Kyolic Kyo-Dophilus Multi 9 Probiotic for Strong Gut

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– Diverse Multi-Strain Probiotic
This multi-strain blend can help populate your microbiome with beneficial bacteria to promote strong GI health and help you maintain a balanced digestive and immune system

– Balanced Digestive Support
This probiotic is specifically formulated to maintain good colon health, relieve occasional digestive discomfort, promote healthy digestive balance and general well-being*

– The Friendly Trio Bacteria
Our proprietary blend of three clinically studied strains, L. gaseri, B. bifidum and B. longum, that have been shown to be efficacious for digestive and immune health*

– Strong Digestive Support
This probiotic is specifically formulated to provide maximum support when your digestive health has been compromised by travel, stress or medication use

Ratings
4.6 out of 5 – more than 650 global ratings

Kyolic Kyo-Dophilus Multi 9 Probiotic for Strong Gut Reviews
This is the only one out of 4 probiotics that helped my histamine intolerance. It was so severe that I ended up in ER 4 times.
So glad that it wasn’t my heart, and I don’t do surveys, but if I can somebody and share my experience check your histamine levels, if you
had suddenly hypertension, ear issues, fluttering diaphragm, heart palpitations, eliminate high histamine veggies and fruits,
you will fell better and get a dao supplement. diamine oxidase.Study histamine intolerance and go gluten free.

B. Diamine Oxidase Supplement for Histamine Intolerance

Healthy Gut

Diamine oxidase (DAO) is an important digestive enzyme in your body to break down histamine obtained from foods.

You might have diamine oxidase insufficiency if your body doesn’t make enough DAO. ‌Moreover, you may also develop histamine intolerance, also known as food histaminosis or enteral histaminosis, if you don’t have enough of this enzyme. When you consume histamine-containing meals, this may make you feel sick

Fortunately, DAO is available as a supplement and has been widely used for treating people with histamine intolerance. DAO will help restore the diamine oxidase enzyme in their bodies, which helps them digest foods high in histamine and may lessen their symptoms.

What Foods Block DAO Production?

alcohol
black tea
mate tea
green tea
energy drinks

4. Bravado Labs DAO Enzyme Supplement for Food-Derived Histamine Intolerance

Bravado Labs DAO Enzyme Supplement for Food-Derived Histamine Intolerance

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– Eat Histamine-rich Foods
If wine and cheese parties end with you sniffling, sneezing, or worse, Bravado Labs histamine block can help by increasing your levels of DAO, which in turn helps your body to break down histamines commonly found at high levels in alcohol, cheese, certain vegetables, shellfish, smoked meats, and other fermented foods.

– Reduce Histamines on the Go
With this small, 30-capsule bottle of our DAO supplement, you can add DAO whenever the occasion calls for it. Just take one capsule 15-30 minutes prior to consuming histamine-rich or DAO-blocking food or drink.

– Relief in One Capsule
While other histamine blocking or DAO supplements may require you to take multiple capsules, our Bravado Labs formulation provides the antihistamine power you need with just one capsule.

– Made the Right Way
Each capsule is vegan friendly, gluten free, and contains no major food allergens with entirely non-GMO ingredients.

– Feel the Difference
If high-histamine foods make you miserable, our histamine block may be able to lessen or eliminate your symptoms. If you’re not satisfied with the results, just let us know within 30 days for a full refund. Eat, drink and be merry – order yours today and alleviate your histamine intolerance!

Bravado Labs Premium Histamine Blocker Reviews
I was very happy to find this product. I have developed histamine intolerance due to Long Covid. My doctor recommended a product like this to take before eating but the one she recommended was much more expensive. In addition to a low histamine diet, this product helps!

5. Omne Diem DAO Histamine Neutralizing Enzyme

Omne Diem DAO Histamine Neutralizing Enzyme

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– Digestive Enzymes for Histamine Intolerance
An effective enzyme solution to histamine intolerance and imbalance.
Alcoholic beverages – particularly red wine – present a triple threat to histamine sensitive people, because they contain histamine, they liberate histamine, and they block the action of dao. Diamine oxidase (dao) is your body’s first-line defense against histamine ingested through the diet or released within the gut.

– Natural Ingredients
Omne diem direct histamine neutralizing enzyme is gluten-free, non-GMO, soy-free, non-dairy, food grade diamine oxidase – with no artificial preservatives or sweeteners.

How to Use:
Take omne diem direct histamine neutralizing enzyme about 15-30 minutes prior to consuming high histamine foods and beverages, to help your body break down histamine and reduce the allergy-like reactions of histamine intolerance.

Omne Diem Diamine Oxidase Supplement Reviews
I have histamine intolerance, which is a subset of mast cell activation syndrome. I like this product because it allows me to eat forbidden foods that without, would cause me a great deal of pain (migraines, abdominal pain, skin rashes, etc.) . It is important to take 15 minutes prior to eating for best absorbency. They are easy to swallow and have no taste.

This product has allowed me to eat holiday meals with friends and family without bringing my own “safe meal”. Histamine Digest replaces the DAO enzyme my body no longer makes. I still eat a low FODMAP diet, and this product allows me to make exceptions to the very long forbidden foods list. I’m a fan for life!


6. NaturDAO Diamine Oxidase Enzyme Supplement Histamine Blocker

NaturDAO Diamine Oxidase Enzyme Supplement Histamine Blocker

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– Greatest Enzymatic Activity on the Market
With 1,000,000 hdus / 32,1mg of vegetable protein, it is the most powerful dao enzyme you can get to reinforce your digestive system.

– Best Natural Choice
If you are going to take it for a long period of time along with your diet. It is suitable for vegans.
No food colours or genetically modified organisms maximum respect in the formulation for a healthier product.

– Fast Availability Tablets in Human Intestine Tested by Radiological Test.

NaturDAO Diamine Oxidase Enzyme Supplement for Histamine Intolerance Reviews
One of the best things for Histamine issues or intolerance. Finally glad to see it available easily in the USA

C. Vitamin C, Stinging Nettle, Quercetin, Bromelain

Sinus or Allergies

You might be able to regulate your seasonal allergies with natural antihistamines. Stinging nettle, vitamin C, quercetin, butterbur, bromelain, and probiotics are some examples. Exercise, acupuncture, and other complementary therapies may also help you control your symptoms. However, do not stop using antihistamines or start using herbal or dietary supplements before consult your doctor.

7. ForestLeaf Quercetin with Bromelain, Vitamin C and Stinging Nettle

ForestLeaf Quercetin with Bromelain, Vitamin C and Stinging Nettle

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– Immune Health
Take care of your immunity with quercetin 500mg supplements. Using a complex blend of quercetin and bromelain, your immune-boosting supplements may support sinus relief, allergies, cardiovascular and respiratory health.

– With Stinging Nettle
Every pill contains stinging nettle leaf extract. It contains a wide variety of nutrients that may assist in balancing your natural response for happier living.

– Naturally Formulated
With a unique blend of natural ingredients including stinging nettle and 200 mg of vitamin C, your 90 capsules quercetin bromelain supplement is vegetarian-friendly to naturally enhance your overall immune health.

– A Daily Dose of Well-Being
Your super quercetin supplements contain stinging nettle leaf extract packed with nutrients that may improve your body’s natural response for daily balance and well-being. The best quercetin supplements for better living!

– Manufactured Safely
ForestLeaf supplements are made with vegetable capsules and are dairy, gluten, egg and nut free. All of its products and pills are tested for maximum absorption. There are 45 servings per bottle, 200mg of vitamin C per serving.

Ratings
4.8 out of 5 – more than 6,400 global ratings

ForestLeaf Quercetin, Bromelain, Vitamin C, and Stinging Nettle Reviews
This is my 3rd bottle of Quercetin with Bromelain by ForestLeaf. I selected this brand because it most closely matched a product by Dr Becky Campbell for histamine relief. I take 2 caps daily but take an additional dose if I’m exposed to something that sets off my allergies.

Quercetin is also helpful in preventing or lessening the severity of colds and flus. The formulation also includes Vitamin C, stinging nettle and bromelain, which are excellent as well.

This product is nearly perfect. I prefer to not take ascorbic acid as it is an inferior vit C and may be an anti nutrient. I know that can be more costly but hope ForestLeaf will consider making the switch in the future.


8. Solaray Quercetin & Bromelain + Vitamin C

Solaray Quercetin & Bromelain + Vitamin C

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– effective blend of quercetin, bromelain & vitamin c for healthy immune support
– hardworking complex may help support normal, healthy sinuses & respiratory function
– quercetin is designed to support sinus health & bromelain may help support absorption
– eco-friendly; committed to a cleaner planet, we use 100% pcr recycled plastic bottles in our product
– manufactured in our own facility, vegan & lab verified for potency & purity

Ratings
4.7 out of 5 – more than 800 global ratings

Solaray Quercetin & Bromelain + Vitamin C Reviews
This is the best supplement I’ve found to keep my histamine levels under control. Will definitely continue to buy!

9. NOW Supplements, Respir-All™ with Quercetin, Vitamin C, Nettle Extract and Bromelain

NOW Supplements, Respir-All™ with Quercetin, Vitamin C, Nettle Extract and Bromelain

Buy on Amazon

– Respiratory Support Supplement
Includes key vitamins, minerals, and herbal extracts that nutritionally supports healthy respiratory functions. Features quercetin, vitamin C, nettle extract, and bromelain in an oval tablet.

– Vegan
Take three tablets daily on an empty stomach (or with food for sensitive stomachs).

– GMP Quality Assured
NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).

Ratings
4.5 out of 5 – more than 700 global ratings

NOW Supplements, Respir-All™ Reviews
Changing my life with histamine intolerance. No more need for benadryl! I have to keep these on hand or I would be miserable.

10. Nature Sunshines Histamine Block

Nature Sunshines Histamine Block
Buy on Nature Sunshines

Don’t let seasonal irritants and pollutants interrupt your life. When pollen and dust start wreaking their havoc, try blocking them with histablock! Nature’s sunshine’s unique herbal blend features stinging nettle, quercetin and bromelain to help you breathe easier.

– supports respiratory system health and function, especially during seasonal changes
– promotes healthy airways for better breathing
– neutralizes free radicals

Nature Sunshines Histamine Block Reviews
I use HistaBlock mostly during the Spring and Fall to help with seasonal allergies. This is a capsule so there is no taste to it. I start taking a month or two BEFORE the seasonal transistion and continue thru the first month of each new season. This has always supported me in having a more positive seasonal transistion!!

FAQ

a. What Foods To Avoid If You Have Histamine Intolerance?


b. Histamine Intolerance vs Allergies

Some signs of histamine intolerance mimic an allergic reaction. However, because of differences in the body’s cellular response, skin tests and blood allergy tests will come back negative.

Histamine buildup is thought to be the cause of histamine intolerance. As a result, the symptoms might not show up right away.

c. How to Clear Histamine From Body?

i. Start a diet that only involves foods and beverages with low amounts of histamine.

ii. You can take histamine blockers or antihistamines might be used to temporarily ease the symptoms.

iii. Use air purifier. Reduce your exposure to irritable irritants and allergens in your environment by using an air purifier. Pet dander, dust, pollen, and mold spores are just a few examples of the allergens that air purifiers remove from the air in your surroundings.

iv. Natural Histamine Blocker. You might be able to regulate your seasonal allergies with natural antihistamines. Stinging nettle, vitamin C, quercetin, butterbur, bromelain, and probiotics are some examples. Exercise, acupuncture, and other complementary therapies may also help you control your symptoms. However, do not stop using antihistamines or start using herbal or dietary supplements before consult your doctor.


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