Best Natural Anti Inflammatory Supplement 2023

What is Inflammation?

Your immune system is triggered when your body is exposed to a pathogen (such as viruses, bacteria, or toxic substances) or sustains damage. Inflammatory cells and cytokines are the first responders that your immune system sends out. 

In order to trap bacteria and other harmful substances or to begin healing damaged tissue, these cells produce an inflammatory response. As a result, you may experience pain, bruising, swelling, or redness. Inflammation, however, also affects body systems.

Acute Inflammation vs Chronic Inflammation

Acute inflammation is an immediate, adaptive response that can be brought on by a number of unpleasant stimuli including infection and tissue injury. 

But if your body releases inflammatory cells even when you are healthy or uninjured, you may have chronic inflammation. For instance, in rheumatoid arthritis, inflammatory cells and substances attack the joint tissues, causing an irregular inflammation that can seriously harm joints and result in pain and deformity. 

When Should I Consult the Doctor About Inflammation?

If inflammatory cells stay too long, it may result in chronic inflammation. Chronic inflammation is a symptom of other medical conditions, for instance, rheumatoid arthritis. 

Therefore, it is advised that you consult your healthcare practitioner if you have a concerning injury. If you experience persistent pain, bruising, stiffness, or other symptoms, speak with your healthcare professional as well. A healthcare professional can identify the root problem and identify treatments that will make you feel better.

How Can I Get Rid of Inflammation?

– Anti-Inflammatory Diet

Researchers have identified certain foods that can help control inflammation. Many of them are found in the so-called Mediterranean diet, which emphasizes fish, vegetables and olive oil, among other staples.

There’s a standardized research tool that’s updated regularly that allows anybody to see if they’re eating foods we know cause chronic inflammation. This is called the The Dietary Inflammatory Index or DII. The choices of pro-inflammatory foods were initially based on studies showing that certain foods like trans-fatty acids (unsaturated fats) caused a spike in serum inflammatory markers in people.

– Autoimmune Protocol Diet

The Autoimmune Protocol (AIP) is a diet that aims to reduce inflammation, pain, and other symptoms caused by autoimmune diseases, such as lupus, inflammatory bowel disease (IBD), celiac disease, and rheumatoid arthritis (Pubmed).

Many people who have followed the AIP diet report improvements in the way they feel, as well as reductions in common symptoms of autoimmune disorders, such as fatigue and gut or joint pain. Yet, while research on this diet is promising, it’s also limited.

The AIP diet is an elimination diet designed to help reduce inflammation or other symptoms caused by autoimmune disorders.

It’s comprised of two phases designed to help you identify and ultimately avoid the foods that may trigger inflammation and disease-specific symptoms. Research on its efficacy is limited but appears promising.

Due to its limited downsides, people with autoimmune disorders generally have little to lose by giving it a try. However, it’s likely best to seek guidance from a qualified health professional to ensure you continue to meet your nutrient needs throughout all phases of this diet.

- Control Blood Sugar

It has been hypothesized that consuming a lot of added sugars and sugar-sweetened beverages (SSBs) can promote chronic inflammation. It is best to restrict or stay away from simple carbs like white rice, white flour, refined sugar, and anything that contains high fructose corn syrup.

- Exercise/Physical Activity

Consistent data from observational studies showing a link between self-reported levels of physical activity and inflammatory biomarkers, as well as some promising positive data from randomized, controlled trials, indicate that increasing aerobic physical activity could be effective for reducing chronic inflammation, especially in individuals with chronic diseases associated with a state of elevated inflammation. (Source)

- Manage Stress

Best Natural Anti-Inflammatory Supplements

A. Turmeric/Curcumin

Turmeric, a spice long known for its therapeutic benefits, has caught the interest of medical world because it is the primary source of the polyphenol curcumin.

Curcumin has been shown to aid in the treatment of oxidative and inflammatory conditions, metabolic syndrome, arthritis, anxiety, and hyperlipidemia. It may also help in the management of exercise-induced inflammation and muscle soreness, thus enhancing recovery and subsequent performance in active people. (Source). Furthermore, a low dose can provide health benefits to persons who do not have documented health concerns.

1. Nature's Nutrition Turmeric Curcumin with BioPerine

Turmeric Curcumin with BioPerine 1950mg - Natural Joint & Healthy Inflammatory Support with 95% Curcuminoids & Black Pepper for Maximum Potency & Best Absorption, Tumeric Supplement - 240 Capsules


- High Potency Turmeric Curcumin
Our premium T3 Turmeric Curcumin Complex 1950mg; with 95% standardized curcuminoids and 15mg BioPerine (black pepper) provides maximum potency; absorption and high bio-availability

- Effective Ingredients
Turmeric is arguably one of the most powerful herbs on the planet; Curcumin; is one of the primary compounds in turmeric powder; is a natural antioxidant; providing natural joint and healthy inflammatory support

- With Bioperine for Best Absorption
BioPerine; a patented black pepper extract; has been shown to improve the absorption of many herbs and spices; and provides as much as 2000x better absorption than consuming normal turmeric capsules alone

- Trusted Formula
Our Turmeric is formulated and manufactured in the USA following strict cGMP guidelines; Our Turmeric with BioPerine is third party tested to assure the quality and purity of each batch

4.6 out of 5 - more than 64,700 global ratings

This works to help with pains I have in my neck and back. I took a different turmeric product before and notice results but ran out and some time passed before I bought this one and in that time I noticed I was getting more aches in my neck and shoulders but when I take this turmeric about 90% of the pain goes away after a few days of taking it. I make sure to take it every morning and now I dont get pain nearly as much as I used to. Ive had zero side effects from this and have been taking it for months. It really does a good job reducing inflammation.

2. Garden of Life Turmeric Supplement

Supports the body’s healthy inflammatory function and antioxidant response. 100mg curcumin from organic whole turmeric root - plus ginger root - both fermented to support bioavailability. Probiotics & organic black pepper extract for enhanced digestion

Nutrients from real foods using water extraction & clean tablet technology with 100% organic & non-GMO tablet materials - no soy or corn-derived ingredients. Certified USDA Organic, Non-GMO Project Verified, NSF Certified Gluten Free, Certified Vegan & Kosher

4.7 out of 5 - more than 6,700 global ratings

My grandma has arthritis and chronic leukemia. I didn't expect this to work as well as it did. While I'm into "natural" or holistic medicine, I prefer the clinical remedies. My grandma is the opposite. I did a little research and decided to get this for her because her shoulder was causing her so much pain that she was struggling to get around and seemed to be very uncomfortable. The FIRST day she took it, that night she seemed to be doing a little better. It's been a week now and her shoulder doesn't seem to bother her at all, only a little. She gets around just fine again. It can't be a placebo effect because I didn't explain much about it, just that it can help ease inflammation in the body. I got her vitamin D and C as well.

B. Fish Oil

EPA and DHA can reduce inflammation, which causes swelling and pain. Research has indicated that both acids might suppress the body’s immune system. However, a 2016 study suggests that DHA might enhance immune function instead. DHA is more effective at reducing inflammation than EPA, but both have a role.

All of these effects makes fish oil potentially beneficial for people with arthritis.

For the omega-3 fatty acids in fish oil to work against arthritis, it’s necessary to consume a fairly large quantity of it each day. Fish oil — or cod liver oil — enclosed in capsules makes this fairly easy.

On the other hand, because cod liver oil contains very high amounts of vitamin A and vitamin D, taking too much can be toxic. For the purpose of treating arthritis, fish oil is the safer choice.

3. Nature Made Fish Oil 1000 mg

- Heart Healthy Omega 3s
The omega 3s EPA and DHA found in fish oil help support a healthy heart.

- 125 Day Supply
Each serving (2 softgels) of this fish oil supplement provides 600 mg of heart-healthy omega 3 fatty acids (500 mg EPA and DHA). Adults take 2 softgels daily with water and a meal.No Preservatives

- Deep Ocean Fish
Deep ocean fish naturally offer an abundance of healthy omega-3s. Nature Made Fish Oils come from wild caught, deep ocean water fish—not farm raised fish.

- High Quality Ingredients
Made from carefully selected ingredients under strict manufacturing processes. Purified to remove mercury and other contaminants.(1) No color added. No artificial flavors. Gluten-free. Dairy-free.

- Safety Checked
Because Nature Made is committed to quality and purity, this fish oil supplement is also USP Verified, an independent organization that tests for quality and purity.

4.8 out of 5 - more than 33,000 global ratings

Will continue to buy these! Great for brain health and inflammation. No taste and easy to swallow

4. Viva Naturals Triple-Strength Omega 3 Fish Oil

- No Fishy Aftertaste
There’s nothing worse than the fishy aftertaste left by lower-quality fish oils. Our omega-3 supplement is highly concentrated to give you clean, high quality oil with no fishy burps or aftertaste.

- Omega-3 for Heart, Brain, Skin & Eye Health*
Science has shown that not only do the omega-3s in fish oil offer cardiovascular support for men and women, but they also promote brain health, and help keep your skin and eyes healthy as you age.*

- Designed for Better Absorption
The omega 3 fatty acids in our fish oil are delivered in triglyceride form. Triglycerides have been clinically shown to be more easily absorbed by your body. This helps you get the most out of every serving.

- IFOS 5 Star Certified 
Our fish are wild caught using sustainable fishing practices – never farm raised. Plus, we use a combination of small fish (like sardines and mackerel), known to have less mercury and fewer toxins than bigger fish like salmon. Each batch is rigorously tested for purity and IFOS 5-Star Certified, a ranking system for premium quality fish oil.

4.7 out of 5 - more than 8,350 global ratings

After much research, this product is the one I chose. It really does help with pain of arthritis. It's not a painkiller, but helps to reduce the inflammation that in turn helps reduce the pain.

C. Ginger

According to studies, ginger supplements have an anti-inflammatory impact. The majority of these research focused on conditions connected to arthritis, particularly osteoarthritis (OA). 

A study investigates the effect of ginger supplementation on proinflammatory factors in participants of a randomized double-blind placebo-controlled 3-month clinical trial investigating knee osteoarthritis. The results of this study indicate that ginger supplementation may have a promising benefits for knee osteoarthritis.

5. Nature's Nutrition Curcumin with BioPerine & Ginger

- High Potency Turmeric & Ginger
Our premium T3 Turmeric Curcumin Complex 1950mg; with 95% standardized curcuminoids; and enhanced with 15mg BioPerine and Ginger to provide maximum potency; absorption and bio-availability

- Effective Ingredients
Turmeric and Ginger are arguably the most powerful herbs on the planet; Curcumin; is one of the primary compounds in turmeric powder; is a natural antioxidant; providing natural joint and healthy inflammatory support

- With Bioperine and Ginger for Absorption
BioPerine; a patented black pepper extract; with ginger has been shown to improve the absorption of many herbs and spices; and provides as much as 2000x better absorption than consuming normal turmeric capsules alone

- Trusted Formula
Our Turmeric Curcumin is formulated and manufactured in the USA following strict cGMP guidelines; Our Turmeric with BioPerine and Ginger is third party tested to assure the quality and purity of each batch

4.6 out of 5 - more than 47,900 global ratings

Love this product, I have Osteoarthritis which is painful every day. Since taking this my pain levels have definitely decreased. Not gone, but much relief compared to other products I have tried.

6. Nature's Way Ginger Root

Nature's Way Ginger Root is a ginger supplement that contains 1,100 mg per serving, providing traditional digestive support. Nature’s Way brings you the best herbals available and sources ginger from where it grows best, like India and West Africa. Made with wholesome ingredients: Non GMO Project Verified, Gluten-free and vegan. No salt, yeast-derived ingredients, dairy, wheat, corn, soy, or artificial colors, flavors, or preservatives.

4.7 out of 5 - more than 12,200 global ratings

Thanks to a friend who introduced me to this product. I love that it has no additives to it. It has helped my digestion issues as well as bowel movements. Also it has helped with my blood sugars. It has helped with my inflammation issues. Will be buying again.

D. Resveratrol

Resveratrol is a class of plant micronutrients called polyphenols. Resveratrol contains antioxidant and has anti-inflammatory effects that can protect you from diseases such as cancer, diabetes, and Alzheimer’s, 

You can find resveratrol in foods such as peanuts, pistachios, grapes, red and white wine, blueberries, cranberries, and even cocoa and dark chocolate.

7. NOW Supplements, Natural Resveratrol

NOW Supplements, Natural Resveratrol

- Free Radical Scavenger*
Resveratrol is best known for its cellular anti-aging properties and ability to promote a healthy response to stress*

- With Red Wine Extract
Easy way to benefit from the polyphenols naturally found in grapes and wine without imbibing

- Certifications/Classifications
Dairy Free, Egg Free, Made without Gluten, Non-GMO, Nut Free, Soy Free

- GMP Quality Assured
NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).

4.7 out of 5 - more than 1,100 global ratings
i really like all the NOW products, especially Natural Resveratrol. I always read the list of ingredients and like the purity of this product.

8. Nutricost Resveratrol 500mg

Nutricost Resveratrol contains 500mg of potent, high-quality Resveratrol per serving. These capsules are non-GMO, Soy Free, and gluten-free.

- potent & high quality resveratrol
- made in a GMP compliant facility
- 500mg of resveratrol per serving

Resveratrol has been the subject of an enormous amount of interest and study regarding its potential to effect a number of areas of human health. If you are interested in this topic, simply visit PubMed and use the search term "Resveratrol". This specific product from Nutricost is an excellent value, due to its high potency and the number of capsules provided in each bottle (i.e. 120). It is rare to get this combination of potency and quantity, especially at this price. I highly recommend it!


a. Who Should Not Take Curcumin?

If you have any of the following health conditions, please consult a doctor before consuming curcumin.
– Diabetes
– Gallbladder problems
– An iron deficiency
– Bleeding problems or a blood-clotting disorder
– A stomach disorder called gastroesophageal reflux disease (GERD);
– Endometriosis or uterine fibroids; or
– Cancer of the breast, uterus, ovary (or other hormone-sensitive conditions).

What should I avoid when taking turmeric?
Turmeric may make it more difficult for your body to absorb iron. Inform your doctor if you use an iron supplement.

Don’t use turmeric with other herbal/health products that may interfere with blood clotting. Angelica (dong quai), capsicum, clove, dandelion, danshen, evening primrose, garlic, ginger, ginkgo, horse chestnut, Panax ginseng, poplar, red clover, saw palmetto, and willow are all included.

Avoid combining turmeric with other herbal/health products that can lower blood sugar levels, such as alpha-lipoic acid, chromium, damiana, devil’s claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, Siberian ginseng, and others.

b. What Are the Side Effects of Resveratrol?

Short-term dosages of resveratrol do not appear to have any side effects (1.0 g). Otherwise, unpleasant effects such as nausea, vomiting, diarrhea, and liver dysfunction may occur at dosages of 2.5 g or more per day in patients with non-alcoholic fatty liver disease. (Source)

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