Stem Cell Supplements Malaysia 2023: Can Stem Cell Supplements Boost Natural Stem Cells?

By
If you do a search on popular e-commerce sites in Malaysia like Shopee and Lazada, you will see many stem cell related products available. Do stem cell supplements really work?

The main claim of these stem cell supplements is that they’ll either make you have more stem cells, happier stem cells, or assist in stem cells differentiating into the desired cell type.

If you do a search on Clinicaltrials.gov, you will find many studies of the effects of specific supplements on stem cells.

stem cell supplements

But do they work?

It’s hard to say without more data. We can only be definitive once we have more quality studies published. We’ll see in coming years or decades if any specific supplement can convincingly do something useful that is stem cell-related based on more research data.

Best natural stem cell boosts?

How might we all increase or stimulate the number of our own stem cells?

However, below are best possible simple and evidence-based ways that research suggests theoretically might be helpful to give your existing so-called endogenous stem cells a boost. 
  • Exercise
  • Caloric restriction and fasting
  • Sleep
  • Protect Yourself from Radiation
Important: consult with your doctor before considering any of these ideas. This blog post is not meant as medical advice.

 Stem Cells - The Basics

Stem cells are undifferentiated cells, unlike the specialised cells in our body such as nerve cells, muscle cells and blood cells. They are capable of developing into various types of cells and tissues. In the human body, stem cells serve as an internal repair system during early growth and throughout life. When a stem cell divides, it potentially differentiates into another type of cell with a more specialised function, e.g. a red blood cell or a nerve cell. To put it simply, stem cells build tissues when and where the body needs them.

Stem cells can be distinguished from other types of cells by these unique properties: (1) they are unspecialised ‘immortal’ cells, capable of dividing many times over, sometimes after long periods of inactivity; (2) under certain conditions, they can be induced to differentiate into specific cell types. In the gut and bone marrow, stem cells regularly divide to replace worn out tissues. In the heart and pancreas, however, stem cells only divide under stressed conditions.

There are three major types of stem cells of the human source:
  1. Human embryonic stem cells (hESCs) are derived from human embryos blastocyst generated through an in vitro fertilisation (IVF) procedure for reproductive purposes. The embryos were collected from fertility clinics via informed consent of donors.
  2. Adult (somatic) stem cells reside in specific tissues and normally grow to replace a particular type of tissue within its surroundings. It is essentially an undifferentiated cell found among differentiated cells in a tissue or an organ, silently in-waiting to act to repair or replace damaged or worn tissues. For example, stem cells in the bone marrow differentiate into several types of blood cells. This ability makes it possible to perform bone marrow transplant from a donor to regenerate a complete blood system in a recipient.
  3. In addition to the above, current technology allows the reversal of a specialised cell into an embryonic stem cell. This reprogrammed cell is called an induced pluripotent stem cell (iPSC).
What are the common terms used to describe stem cells?

Stem cells can be classified according to their developmental versatility, or ‘plasticity’. This indicates how committed a stem cell is to differentiate and become a particular type of cell.

Totipotent stem cells:
The most versatile of stem cell types, they have the potential to give rise to any and all cells or even an entire organism. When a sperm cell and an egg cell unite, a one-celled totipotent fertilised egg is formed.

Pluripotent stem cells:
These stem cells can give rise to all tissue types but cannot give rise to an entire organism (unlike totipotent stem cells). Eg: human embryo stem cell or blastocyst.

Multipotent stem cells:
These stem cells are more differentiated and can only give rise to a limited range of cells, e.g. within a tissue type.

Adult stem cells:
These are multipotent stem cells that are undifferentiated cells present in a differentiated tissue, functioning to replace dead or damaged cells.

Another group of stem cell products that have gained prominence in Malaysia is the “Double Stem Cell” and “Triple Stem Cell” products by companies producing cosmetic and nutritional supplements extracted out from the stem cell of plants. These stem cell products are different from 'live' stem cells that are used in most of the stem cell therapy studies and clinical trials.

What are the possible applications of stem cells in medicine?

Given their unique differentiation abilities, stem cells offer much potential in medicine. Use of stem cell based therapies for treatment of diseases is referred to as regenerative medicine. Regenerative medicine has often been perceived as the next pillar in healthcare, after pharmaceutical drugs, biological products and medical devices.

As clinical application of stem cells will require safe and highly efficient generation of stem cells, fundamental scientific research attempts to answer these questions:

(1) why can embryonic stem cells proliferate for a long period without differentiating, while adult stem cells cannot?;

(2) what are the factors in the human body that regulate stem cell proliferation and self-renewal?

The answers to these questions may provide a deeper understanding on how cell proliferation is regulated during normal embryonic development or during uncontrolled cell division that leads to cancer or birth defects. The information may also allow more efficient generation of stem cells in the laboratory setting to fulfil medical needs. In mouse studies, embryonic stem cells have been successfully differentiated into nerve cells and insulin-producing cells. If the technique can be successfully replicated in human, transplantation of laboratory-produced specialised cells can potentially treat diseases such as diabetes, traumatic spinal cord injury, and Parkinson’s disease.

Conclusion
In conclusion, a complete understanding on the potential of stem cells in medicine presents a great challenge to the medical community. However, rapid developments in genomics and proteomics can potentially widen the horizon for clinical application of stem cells. The ultimate aim is to transform stem cell therapy from a medical frontier to a medical basis one day.


References:
  1. National Institutes of Health, U.S. Department of Health and Human Services (March 5, 2015). Stem Cell Basics: Introduction. In Stem Cell Information. Retrieved April 14, 2015 from http://stemcells.nih.gov/info/basics/pages/basics1.aspx
  2. National Institutes of Health, U.S. Department of Health and Human Services (September 9, 2009). Stem Cell Information: Repairing the Nervous System with Stem Cells. Retrieved April 15, 2015 from http://stemcells.nih.gov/info/scireport/pages/2006Chapter3.aspx
  3. Nature Publishing Group (2015). Nature Reports: Stem Cells FAQs: What are Stem Cells? Retrieved April 14, 2015 from http://www.nature.com/stemcells/2007/0706/070614/full/stemcells.2007.12.html
  4. Nature Publishing Group (2015). Nature Reports: Stem Cells FAQs: How can Stem Cells Advance Medicine? Retrieved April 14, 2015 from http://www.nature.com/stemcells/2007/0706/070614/full/stemcells.2007.23.html
  5. Nature Publishing Group (2015). Nature Reports: Stem Cells FAQs: What are Some Risks of Stem Cell Therapies? Retrieved April 14, 2015 from http://www.nature.com/stemcells/2007/0706/070614/full/stemcells.2007.26.html
  6. Brown University, Division of Biology and Medicine (February 19, 2014). Courses: Stem Cell Classification. Retrieved April 14, 2015 from http:www.biomed.brown.edu/Courses/BI108/BI108_2002_Groups/pancstems/stemcell/stemcellsclassversatility.htm
  7. Winslow, T. How Human Embryonic Stem Cells are Derived (2006) [Image]. Retrieved April 15, 2015 from http://www.stemcells.nih.gov/info/scireport/pages/2006Chapter1.aspx
  8. Medical Development Division, Ministry of Health Malaysia (2009). Guidelines for Stem Cell Research and Therapy. Retrieved April 14, 2015 from http://www.moh.gov.my/images/gallery/Garispanduan/Stem_Cell/stem_cell_therapy.pdf
  9. Strauer, B.E. and Kornowski, R. (2003) Stem cells therapy in perspective. Circulation; 107: 929-934. Retrieved April 15, 2015 from http://www.circ.ahajournals.org/content/107/7/929.full.pdf+html
  10. https://ipscell.com/2020/02/review-of-stem-cell-supplements-underscienced-overpriced/
  11. https://ipscell.com/2014/07/top-5-possible-natural-stem-cell-boosts/
  12. http://www.nature.com/stemcells/links.html 
Related: 

Comments

Post a Comment

Popular posts from this blog

NAC vs NAD vs NR vs NMN vs Niacin: What Are the Differences?

By
Image
NAC vs NAD vs Niacin vs NR vs NMN . Due to the small alphabetical differences, these supplements are often mixed up and confused by most consumers. We will cover the essentials and explain about each of these supplements below. Contents NAD NAD vs NAD+ NAD+ for Anti Aging NAD+ Helps Restore Age-Related Muscle Deterioration NAD and Resveratrol NAD Supplements NAC Niacin (NA) NR NMN NAC vs NMN Gluthatione vs NAC NAC vs Niacin NR vs NMN Can you take NR and NMN together? Niacin vs NR vs NMN Stability and Storage of NMN and NR Naturally Boosting NAD Levels Related Articles NAD NAD is a type of coenzyme found in all living cells. NAD plays important roles in a variety of metabolic reactions, including energy production and DNA repair. NAD is derived from Nicotinamide Riboside (NR) and various other precu
Read more

I-LONGEVITY Protocol: Anti Aging Guide to Help People Prevent and Reverse Aging (2024)

By
Image
Introduction Can diet, lifestyle and supplements reverse your age? Dive into 1,000+ research studies to find out. Current AI tools like ChatGPT, Gemini from Google and Copilot from Microsoft might return generic answers to your questions. While these can be a starting point, they often lack the depth and updated references you might crave for your research. If you are in the anti aging, longevity or biohacking space, chances are you have heard about Dr  David Sinclair  and  Bryan Johnson . Although both of them do share many longevity related strategies, their recommendations might be too overwhelming for an average layperson. You should also consult your doctor before starting any new diet and supplement program to ensure safety and suitability for your individual needs. That's where this guide is all about. We've delved into the research to provide you with more than just basic advice. We've done the research, so that you don't have to. We'll not only share suppor
Read more

18 Best Supplements to Reduce Cytokine Storm: Advanced Guide

By
Image
As of May 2024, there are more than 4,000 early treatment studies  that have been published and shared with the whole world. New ones are being added every day.  This is a review of the literature, covering multiple observational studies, randomized controlled trials and references related to natural supplements and cytokine storm with more than 300 studies and references. We know that while a large percentage of the population only experiences mild to moderate symptoms of COVID-19 and won’t require hospitalization, others experience severe symptoms and complications, require hospitalization, or may even die.  It appears one of the differences between those who have a mild illness and severe illness is related to the body's ability to reduce the hyperimmune response that leads to a cytokine storm and the hyper-coagulability (tendency for blood clots) that often accompanies it. The cytokine storm may be one possible way to explain the
Read more

Zinc Gluconate vs Zinc Picolinate: What's the Difference?

By
Image
Zinc picolinate and zinc gluconate are forms of dietary supplements that we use to prevent zinc deficiency.  Zinc  is an essential mineral that our body can easily absorb. Therefore, if we do not get enough amount of zinc, we may have to take these dietary supplements as directed by the doctor. When choosing a zinc supplement, it’s important to consider the type of zinc, dosage, and supplement form. Types of Zinc Supplements   There are several types of zinc supplements. Supplements contain several forms of zinc, including zinc gluconate, zinc citrate and zinc picolinate. The percentage of elemental zinc varies by form.  Chelated zinc is a general form of supplementary zinc in which the zinc is chelated — or bound — to a compound to make it easier for the body to absorb. Zinc picolinate or zinc gluconate are formed when zinc is chelated to picolinic acid or gluconic acid, so the main dif
Read more

10 Best NMN Supplements (2024 Review)

By
Image
NMN stands for nicotinamide mononucleotide and is a precursor to NAD+, or nicotinamide adenine dinucleotide. NMN is the direct precursor of the essential molecule nicotinamide adenine dinucleotide (NAD+) and is considered a key component to increase NAD+ levels in cells. NAD+ is a critical molecule found in every cell of your body, but levels of NAD+ naturally fall with age, making it — and NMN, as a result — crucial. NMN is one of the most popular supplements in the anti aging community. The global Nicotinamide Mononucleotide (NMN) market was valued at US$ 98.5 million in 2019 and it is expected to reach US$ 296.5 million ( R ) by the end of 2026, growing at a CAGR (Compound Annual Growth Rate) of 7.3% during 2021-2026. The NAD story took off toward the end of 2013 with a  high-profile paper  by Harvard's David Sinclair and colleagues. Sinclair, recall, achieved fame in the mid-2000s for research on yeast and mice that suggested the red wine ingredient resvera
Read more

Private Hospital and Government Hospital Charges in Malaysia

By
Image
Ever wondered How Much Does It Cost to be admitted in a private hospital or a government hospital in Malaysia? Find out and compare hospital charges below. Although the numbers and statistics are everywhere on the internet, we have compiled and organised the information accordingly in one place. The pricing information below is based on the published prices from major centres and pricing information available on blogs and the internet. Here is the list, categorised by Government Hospital Charges and Private Hospital Charges. GOVERNMENT HOSPITAL CHARGES IN MALAYSIA The average cost of popular medical procedures in public hospitals in Malaysia: Angioplasty: RM 200 Cataract: RM 500 / eye Chemotherapy: RM 200/visit Dengue: F.O.C. Heart Bypass: RM 4,000 Hip Replacement: RM 15,000 Kidney Stone: RM 10,000 Spine Surgery: RM 36,000 Stroke: RM 5,000 Additional Medical Costs That You May Need to Pay For Of course, the costs of the medical procedures above aren’t the onl
Read more

12 Best Vitamin D3 Supplements of 2024

By
Image
Vitamin D is a fat-soluble vitamin, meaning that it dissolves in fats and oils and can be stored in your body for a long time. Two main dietary forms exist: Vitamin D3 (cholecalciferol). Found in some animal foods, like fatty fish and egg yolks. Vitamin D2 (ergocalciferol). Found in some plants, mushrooms, and yeasts. The Global Vitamin D Market size was worth US$ 1.1 billion in 2022 ( R ), and it is estimated to reach a valuation of US$ 1.7 billion by the end of 2028, expanding at an annual compound rate of 7.0% between 2023 and 2028. What is Vitamin D Good For? Vitamin D helps keep you bones strong by aiding in the absorption of calcium and phosphorus. It's involved in maintaining a healthy immune system, mood regulation, heart health, and even weight loss .  What is the Best Form of Vitamin D?  Vitamin D is a fat-soluble vitamin, meaning that it does not dissolve in water and is absorbed best in your bloodstream wh
Read more

Dr. Zelenko's Z-Stack Vitamin Cocktail: Review 2024

By
Image
The  Zelenko COVID-19 Protocols  was developed by Dr Vladimir Zelenko. The protocol has as its centerpiece, but not exclusive piece, the combined use of Hydroxychloroquine (HCQ) and Zinc as a means by which a person can both help to prevent or mitigate the contraction of  COVID-19 , or can actually treat the disease once it has been diagnosed.  A  retrospective study  analyzing Dr Zelenko's patient data was accepted for publication after a rigorous peer review process. The study finds that early intervention and treatment of high-risk patients with COVID-19 resulted in significantly fewer hospitalizations and deaths. The treatment consisting of zinc, low-dose hydroxychloroquine (HCQ), and azithromycin, is also referred to as "The Zelenko Protocol." Dr Zelenko has since updated his protocols to incorporate new evidence. He has since evolved his protocols to include a quercetin, zinc, vitamin D and C protocol for low-risk patients as w
Read more

Hydroxychloroquine + Zinc Study: Dr Harvey Risch from Yale (American Journal of Medicine) 2021

By
Image
Early on in the COVID-19 pandemic, doctors around the world reported high success rates using an inexpensive treatment protocol of hydroxychloroquine (HCQ) and zinc, typically in combination with an antibiotic to treat secondary bacterial infections. On July 23, 2020, Dr. Harvey Risch, professor of epidemiology at Yale School of Public Health, published an op-ed in Newsweek in which he expressed his dismay and frustration:3 “I have authored over 300 peer-reviewed publications and currently hold senior positions on the editorial boards of several leading journals. I am usually accustomed to advocating for positions within the mainstream of medicine, so have been flummoxed to find that, in the midst of a crisis, I am fighting for a treatment that the data fully support but which, for reasons having nothing to do with a correct understanding of the science, has been pushed to the sidelines. As a result, tens of thousands of patients with COVID-19 are dying unnecessarily … I am referring,
Read more

PicoWay vs PicoSure vs PicoPlus vs PicoCare: What are the Differences?

By
Image
If you are confused about all the pico laser treatments in town and are looking for a guide to better understand pico laser and pigmentation treatment, you've come to the right place. “Pico Laser” is a recent buzzword in aesthetic medicine, so it's no surprise that Pico Lasers are one of the most popular treatment nowadays. However, the science is also mixed with hype and you are likely to get overwhelmed and cluttered over this Pico Laser treatment. We have compiled related pico laser questions and answers in one place in order to answer the above question and to de-clutter your mind. All answers are provided by medical doctors and dermatologists. The information below is based on published answers from major sites on the internet. Here is the list: Q: I am looking for a treatment for melasma, pore size reduction and rejuvenation. I came across pico technology but what is the difference between Pico Way and Pico Sure ( apart from a manufacturer). Is one better than the
Read more