10 Best NAD+ Supplements to Buy in 2023
It’s the energetic currency keeping your body functioning at its peak. NAD deficiency dramatically speeds up how fast you age.
What is NAD+ and What is its Function?

- Converting food to energy
- Repairing DNA
- Creating androgen hormones
- Building muscles
- Recovery
- Activating a group of seven essential longevity proteins called sirtuins
Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells. It exists in two forms: an oxidized form and a reduced form, which are NAD+ and NADH (H for hydrogen).
It is central to energy metabolism and maintaining proper cell function. It plays a crucial role for our mitochondria function, which turn food and oxygen into energy for our body to use. NAD+ also supports the function of sirtuins. Sirtuins are proteins that help protect cells from age-related decline, regulate biological pathways and turn certain genes on and off. However, NAD+ levels decline with age which drive the aging process.
If you have suboptimal NAD levels, you’ll age faster and have difficultly performing at your peak.Most NAD Supplements Are Fake or Dangerous?
Third-party reports across brands and ingredients have found outright fraud: some products contain absolutely zero of the stated ingredient but rather another unrelated compound instead.Since it’s new, supplement manufacturers and commercial sources have only begun appearing in the last few years. Suppliers cannot match the demand spike. The market and online stores have become littered with fake (and expensive) NAD boosters.
Best NAD Supplements 2023
- Tru Niagen NAD Supplement
- Nutricost Niacinamide
- ProHealth Longevity NMN Pro 500
- Codeage Liposomal NMN + Resveratrol + Quercetin + TMG Supplement
- Life Extension NAD+ Cell Regenerator and Resveratrol Elite
- Nuchido TIME+ Nicotinamide, EGCG, Vitamin C, Alpha Lipoic Acid, Zinc
- Wonderfeel® Youngr™ NMN
- Thorne Research ResveraCel
- aSquared Nutrition Nicotinamide with Resveratrol
- Peak Performance NMN supplement + Resveratrol
1. TRU Niagen NAD+ Booster Supplement
- 30 count / Serving Size: 1 Capsule once a day - Servings Per Container: 30
- 90 count / Serving Size: 1 Capsule once a day - Servings Per Container: 90
- 120 count / Serving Size: 1 Capsule once a day - Servings Per Container: 120
- A clinical trial published in Scientific Reports in 2019 (Read More)
- A study published Nature Communications in 2018 (Read More)
- A study published in Cell Reports in 2019 (Read More)
- A study published in the American Journal of Clinical Nutrition in 2018 (Read More)
- A study published in the American Journal of Clinical Nutrition in 2020 (Read More)
2. Nutricost Niacinamide

3. ProHealth Longevity NMN Pro 500
- Pure NMN Pro 100 Grams Bulk Powder.
- NMN Pro 300
- NMN Pro 1000
- Prohealth Longevity NMN Pro Complete (NMN, Trans-Resveratrol and TMG)
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4. Codeage Liposomal NMN + Resveratrol + Quercetin + TMG Supplement
About this item
- Liposomal delivery matrix: NAD precursor blend offering NMN nicotinamide mononucleotide + resveratrol, betaine, riboflavin, vitamin B12, and quercetin all-in-one through a liposomal phospholipid complex.
- NMN Stabilized Form + Resveratrol: Codeage NMN nicotinamide mononucleotide performance supplement comes in powder-filled capsules for both women and men. This nicotinamide mononucleotide stable blend has been paired with trans-resveratrol, a polyphenol extracted from the root of Japanese knotweed, also know as Polygonum cuspidatum.
- NAD Supplement Precursor & Betaine: This NAD precursor athletic fitness formulation delivers 85 mg of betaine anhydrous in each serving. Also called trimethyglycine (TMG), betaine usually consists of an amino acid derived from plants and sugar beets. NAD has been researched for its role on stem cells, telomere, and cellular energy.
- Riboflavin & Vitamin B12 with Quercetin: Codeage Liposomal NMN formula also combines two of the vitamin B complex essential vitamins as well as quercetin. This formula provides Vitamin B2 as riboflavin-5-phosphate and vitamin B12 as methylcobalamine. These essential vitamins to support the metabolism have been blended with quercetin dihydrate from Japanese sophora flowers.
- Manufactured in the USA: Codeage NMN & resveratrol vitality blend is non-GMO and manufactured in the USA in a cGMP certified facility. This liposomal nicotinamide with riboflavin supplement doesn't contain any fillers, hormones, or artificial ingredients. Third-party tested.
- Liposomal delivery matrix: NAD precursor blend offering NMN nicotinamide mononucleotide + resveratrol, betaine, riboflavin, vitamin B12, and quercetin all-in-one through a liposomal phospholipid complex.
- Suggested use: Take 3 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.
- iHerb Best Seller Product Rank: #2 in Nicotinamide Mononucleotide (NMN) category;
#2 in NAD+ category. - Over 500 customer reviews, most of them 5-stars on iHerb.com.
- Liposomal delivery matrix: NAD precursor blend offering NMN nicotinamide mononucleotide + resveratrol, betaine, riboflavin, vitamin B12, and quercetin all-in-one through a liposomal phospholipid complex.
- NMN Stabilized Form + Resveratrol: Codeage NMN nicotinamide mononucleotide performance supplement comes in powder-filled capsules for both women and men. This nicotinamide mononucleotide stable blend has been paired with trans-resveratrol, a polyphenol extracted from the root of Japanese knotweed, also know as Polygonum cuspidatum.
- NAD Supplement Precursor & Betaine: This NAD precursor athletic fitness formulation delivers 85 mg of betaine anhydrous in each serving. Also called trimethyglycine (TMG), betaine usually consists of an amino acid derived from plants and sugar beets. NAD has been researched for its role on stem cells, telomere, and cellular energy.
- Riboflavin & Vitamin B12 with Quercetin: Codeage Liposomal NMN formula also combines two of the vitamin B complex essential vitamins as well as quercetin. This formula provides Vitamin B2 as riboflavin-5-phosphate and vitamin B12 as methylcobalamine. These essential vitamins to support the metabolism have been blended with quercetin dihydrate from Japanese sophora flowers.
- Manufactured in the USA: Codeage NMN & resveratrol vitality blend is non-GMO and manufactured in the USA in a cGMP certified facility. This liposomal nicotinamide with riboflavin supplement doesn't contain any fillers, hormones, or artificial ingredients. Third-party tested.
- Liposomal delivery matrix: NAD precursor blend offering NMN nicotinamide mononucleotide + resveratrol, betaine, riboflavin, vitamin B12, and quercetin all-in-one through a liposomal phospholipid complex.
- Suggested use: Take 3 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.
- iHerb Best Seller Product Rank: #2 in Nicotinamide Mononucleotide (NMN) category;
#2 in NAD+ category. - Over 500 customer reviews, most of them 5-stars on iHerb.com.
5. Life Extension NAD+ Cell Regenerator and Resveratrol Elite
- NAD+ Cell Regenerator™ and Resveratrol Elite™ is Life Extension's Best in Class formula for energy support. It combines 300 mg of NIAGEN® nicotinamide riboside with an ultra-bioavailable trans-resveratrol (as well as bioavailability-enhanced forms of the phytonutrients quercetin and fisetin) to fight general fatigue and promote longevity with every dose.
- NIAGEN® nicotinamide riboside increases your levels of NAD+, an enzyme critical to healthy cellular energy production. Resveratrol promotes a variety of health and longevity mechanisms; quercetin supports heart and immune health; and fisetin encourages your body to clear senescent cells. This formula combines highly bioavailable forms of all four of these nutrients, creating an unrivaled supplement for energy, vitality and defense against cellular aging.
- iHerb Best Seller Product Rank: #1 in Fisetin category; #2 in Nicotinamide Riboside category.
- Over 1,000 customer reviews, most of them 5-stars on iHerb.com.
6. Nuchido TIME+ Nicotinamide, EGCG, Vitamin C, Alpha Lipoic Acid, Zinc
At Nuchido Laboratories science is at the core of everything they do. This is why they conducted a clinical trial on their next generation NAD+ boosting supplement, Nuchido TIME+.
In this trial, they measured levels of NAMPT (Nicotinamide PhosphoribosylTransferase). This is the key enzyme which powers NAD+ production and recycling (the Salvage Pathway) in youthful cells.
Unfortunately, levels of this enzyme decline as we get older and this is one of the main causes of NAD+ decline.
According to Nuchido, their Nuchido TIME+ is the only product clinically proven to restore NAMPT and fix the root causes of NAD+ decline. Precursor supplements such as NR or NMN fail to fix the Salvage Pathway and therefore, fail to address the root causes of NAD+ decline.
This is why precursor supplements can cause further cellular dysfunction such as methyl donor depletion and inadvertently driving inflammation.
Where to buy Nuchido TIME+: Nuchido TIME+ is available on Nuchido's website. Here is the link: Nuchido TIME+
Note: To get 20% discount on your first purchase, please use this coupon code: ONEDAYMD20
In this trial, they measured levels of NAMPT (Nicotinamide PhosphoribosylTransferase). This is the key enzyme which powers NAD+ production and recycling (the Salvage Pathway) in youthful cells.
Unfortunately, levels of this enzyme decline as we get older and this is one of the main causes of NAD+ decline.
According to Nuchido, their Nuchido TIME+ is the only product clinically proven to restore NAMPT and fix the root causes of NAD+ decline. Precursor supplements such as NR or NMN fail to fix the Salvage Pathway and therefore, fail to address the root causes of NAD+ decline.
This is why precursor supplements can cause further cellular dysfunction such as methyl donor depletion and inadvertently driving inflammation.
Note: To get 20% discount on your first purchase, please use this coupon code: ONEDAYMD20
7. Wonderfeel® Youngr™ NMN
- 450 mg Nicotinamide Mononucleotide
- 2 mg Ergothioneine
- 50 mg Trans Resveratrol
- 40 mg Olea25® (25% hydroxytyrosol)
- 10 mcg Vitamin D3 (Cholecalciferol)
8. Thorne Research ResveraCel (Nicotinamide Riboside with Resveratrol and Quercetin Phytosome)

10. Peak Performance NMN + Resveratrol
About this item
- Not all NMN supplements are created equal! Many supplements come with just NMN, which by itself is less effective to produce higher levels of NAD which the body needs to prevent cellular degeneration as we age. Peak Performance combines NMN with Resveratrol. Resveratrol works synergistically with NMN as it acts as an accelerator to produce better results in DNA repair.
- Anti Aging = NMN + Resveratrol! Our cells use NAD+ to produce energy and to activate proteins that repair damaged DNA. Scientists believe that the decline of NAD+ as we age results in many health-related problems. To sustain healthy levels of NAD+ we can supplement this with its precursor, nicotinamide mononucleotide (NMN) . When combined with Resveratrol this supplement becomes even more powerful. Great for cellular + DNA repair, muscle endurance and strength, vascular health and blood flow.
- What's in your supplement? - Many supplements on the market use standard formulas that may contain cheap fillers and sometimes questionable ingredients. All of our ingredients are carefully chosen and 3rd party tested for purity.
- Vegan & Allergy Free - Free Of Soy, Milk, Egg, Shellfish, Corn, Wheat & Peanuts. Contains NO Gluten or Preservatives. Manufactured Under The Highest Quality GMP Regulations and USA Standards.
64% of NMN Supplements Fail Tests
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Credit: ChromaDex
* The same distributor (SerumLab S&C International LLC)
was listed on the product packaging from 10 of the 22
product brands.
Recently researchers have argued that a transporter exists for NMN
too, which is something that ChromaDex disputes. It claims that NMN must first be converted into NR in the
blood before it can be used by the cells.
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Cost Comparison of various NAD supplements 2023
- Cost per bottle: $58
- Dosage: 500mg
- Cost per gram: $2
- Delivery Method: Capsule
- Cost per bottle: $59.95
- Dosage: 500mg
- Cost per gram: $4.00
- Delivery Method: Capsule
- Cost per bottle: $49.99
- Dosage: 500mg
- Cost per gram: $3.33
- Delivery Method: Capsule
- Cost per bottle: $47
- Dosage: 300mg
- Cost per gram: $5
- Delivery Method: Capsule
NAD+ vs NADH
The key question is what ratio of NAD+ does your body need compared to NADH. While the optimal NAD to NADH ratio remains elusive, research suggests that a generally higher NAD to NADH ratio is favorable.
When it comes to a plain NAD label, it’s not wrong to be identified as a NAD booster. Generating more NAD+ will naturally generate more NADH. However, the specificity of NAD+ is more indicative of what your cells are truly building when using NAD+ boosting supplements.
Read more at NAD+ and NADH: What's the Difference?
How can I increase my NAD+ naturally?
- Exercise- Reduce sun exposure
- Spend more time in warm places, like hot tubs or saunas
- Consume more food with Vitamin B like avocados, steam fish or milk
- Consume fermented food and drinks which contain NAD+ like sauerkraut and kombucha
- Intermittent fasting : Popular fasting plans often include 16- to 24-hour fasting periods twice a week, followed by healthy meals. This eating pattern triggers body shock, which can boost your natural supply of NAD+.- Ketosis Diets : a low-carb, high-protein, healthy fats food plan.
Do NAD+ Supplements Work?
The answer may not be so simple. NAD+ is a ubiquitous and fundamental molecule, involved in many biological pathways and cellular operations. Its ingestion could lead to a mix of positive and negative outcomes, the balance of which might depend on context. NAD+ precursors, consumed orally, may be taken up by some tissues more than others. And different cell types are known to employ distinct metabolic programs, which could lead to tissue-specific responses to NAD+.
Concerns and Cautions: Be aware that some of these NAD supplements provide amounts of vitamin B-3 above the established daily upper tolerable intake level. There is also a theoretical safety concern that compounds that raise NAD+ levels like, nicotinamide riboside, as well as NAD, NADH, and possibly NMN, may promote the growth of existing cancers.
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