15 Best Supplement for Osteoporosis Prevention 2022

Osteoporosis is a health condition that develops when a person loses a significant amount of bone density. Weak and fragile bones are a result of this disease. It takes years to develop and is frequently only discovered after a bone breaks due to a fall or other unexpected incident. 

osteoporosis prevention

Osteoporosis treatment involves medications that are made to slow bone loss or enhance bone density. These medications include bisphosphonates, calcitonin, and estrogen receptor modulators.

Sometimes, taking supplements as part of a medical treatment regimen might enhance bone density and prevent additional bone loss. Read on to find out which vitamins can be beneficial if you have osteoporosis.

Best Supplement for Osteoporosis Prevention

A. Calcium and Vitamin D
B. Magnesium
C. Boron
D. Vitamin K
E. Soy Isoflavones
F. Multivitamin / All in One

A. Calcium and Vitamin D for Osteoporosis Prevention

Studies showed that a combination of calcium and vitamin D supplementation was effective in the preventive treatment of osteoporosis in people aged 50 years or older. The treatment was associated with a reduced rate of bone loss, and fracture risk reduction.

For best therapeutic effect, they recommend minimum doses of 1200 mg of calcium, and 800 IU of vitamin D (for combined calcium plus vitamin D supplementation).

1. Sundown Calcium 1200mg with Vitamin D3 1000IU (25mcg) / per Serving

Sundown Calcium 1200mg with Vitamin D3 1000IU (25 mcg)


- Immune System Support
Calcium with Vitamin D3 helps your immune system stay strong and ready for action*

- Strong Bones, Teeth, Joints
Calcium forms the building blocks that keep your bones, teeth and joints working properly; vitamin D3 aids calcium absorption*

- Essential Sunshine Vitamin
Limiting your UV/sun exposure makes it hard for your body to produce Vitamin D; this clean health supplement satisfies your body’s need for this essential nutrient*

- Nerve and Muscle Protection
Supports good nerve and muscle health so you can maintain your active lifestyle*

- Clean Health Supplement
Non-GMO and free of artificial flavors; gluten-free, wheat-free, dairy-free, lactose-free. Sundown products are always third-party tested for safety, quality and purity. We are a proudly American company with millions of happy customers since 1977

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

4.7 out of 5 - more than 5,050 global ratings

I got tired of not being able to find liquid calcium at the store when I am about out. I found these online and showed them to my doctor. My calcium was low so I faithfully used these for a set amount of time and when I had my calcium levels checked again they were up.
It is about a 3 month supply so easy to re-order when you are almost out. I am pre-osteoporosis so I am taking these daily to maintain bone mass.

The capsules are big but EASY to swallow. The liquid gel caps are easily absorbed. I take two daily, one in the morning and one at night with a vitamin D supplement as recommended by my doctor. Both levels increased after taking for a set amount of time and re-testing levels.
I highly recommend these capsules to thwart off Osteoporosis.
They are very inexpensive if you compare it to even the best of brands.

2. Horbäach Calcium 1200 mg with Vitamin D3 5000 IU / per Serving

Horbäach Calcium 1200 mg with Vitamin D3 5000 IU


- Two Vital Nutrients
Calcium and Vitamin D are two vital nutrients. Horbaach's Absorbable Calcium plus D3 is great for high absorption and designed to support any routine or active lifestyle

- Trusted Supplement
Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed! Moreover, it is naturally free of gluten, wheat, yeast, milk, lactose, flavoring & non-GMO

4.6 out of 5 - more than 3,750 global ratings

Horbaach Calcium with Vitamin D3 Supplement Reviews
I did some researched and read that when you're 50 or over, you should make sure you take 1200 mg's of calcium daily. The bonus is that I also get my daily Vitamin B3!!!

3. Caltrate Calcium 600mg and Vitamin D3 800 IU/per Tablet

Caltrate Calcium with Vitamin D3 Supplement


Caltrate bone health supplements contain 600 mg of calcium per tablet. Help maximize calcium absorption and support healthy bones, joints and muscles. Formulated with calcium carbonate, nature's most concentrated form of calcium. In addition to calcium, your body needs vitamin D to help calcium work for you.*

Take one to two tablets daily with food, or take these bone support supplements as directed by a physician to get the calcium and vitamin D your body needs to support healthy bones and muscles and keep you moving.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

4.8 out of 5 - more than 9,030 global ratings

At least 20 years ago, I was diagnosed with low bone density, which is more common among women. Actually it was 40 years ago that I began to change my eating habits to lose weight. In that I've been a success as I weigh about 70 lbs less than back than & have been this weight for many years. 

But the journey had some side effects, a cutting back on dairy & protein helped lead to low bone density. I don't know how many years ago I began taking these six days a week, and along with more protein and a lot of ice cream, my bone density is nearly back to the "normal" level. I have to credit these tablets as a contributing factor

B. Magnesium for Osteoporosis Prevention

Both low and high magnesium levels have been shown to affect the bones in experimental and epidemiological studies.

Magnesium is a component of the bones. In fact, our bones stores 60 percent of the body's magnesium. It also has a role in the activity of bone-building cells and the parathyroid hormone, which regulates calcium levels.

Those with magnesium deficiency are more likely to develop osteoporosis. In adults with sickle cell anemia, low serum Mg is a contributing cause to osteopenia. Furthermore, pre- and postmenopausal women have been shown to have a link between serum Mg and bone density.

Recommended Dietary Allowances (RDI) for Magnesium:
19–30 years: Male 400 mg, Female 310 mg 
Above 31 years: Male 420 mg, Female 320 mg 

4. Benevolent Nourishment Magnesium Complex 500mg

Benevolent Nourishment Magnesium Complex 500mg


– The best magnesium complex:
This premium supplement contains 500mg of pure magnesium blend — magnesium oxide, magnesium citrate, magnesium taurate, magnesium bisglycinate chelate (TRAACSⓇ), and magnesium aspartate. Each type provides unique health benefits like pain relief and quality sleep, and you get all of them in one supplement instead of buying multiple supplements. Most other formulas only have 1-2 types so with ours, you get more value for your money!

– Get rid of aches and pains:
Our Magnesium Complex supports your muscles, prevents cramps, and reduces headaches! Not only that, it also promotes calmness and better sleep, relieves stress and anxiety, supports your heart, improves digestion, and increases energy levels – all in one daily capsule!

– Keep calm and sleep better:
Magnesium helps ease stress and calms your mind so you can enjoy a relaxing, rejuvenating sleep. Finally, get the rest you need and wake up feeling refreshed and energized – ready to take on anything!

– Max absorption and gentle on the gut:
Our supplement contains patented magnesium bisglycinate chelate (TRAACSⓇ), formulated to survive stomach acid for maximum absorption and benefits. It’s easy on the stomach, to provide you with pain and stress relief without the discomfort.

– Formula you can trust:
With Magnesium Complex, rest assured that you’re getting a superior quality supplement formulated by doctors and complying with strict GMP guidelines. This vegan and non-GMO supplement is safe and tested for purity and potency by a third party laboratory. You deserve the highest quality supplements to improve your health!

4.7 out of 5 – more than 2,400 global ratings

Benevolent Nourishment Magnesium Complex Reviews
As a lady in early menopause, this Magnesium Complex helps with my bone density and also for my heart health and preventing palpitations. Since switching to this brand, I have had great results. I highly recommend it.

5. Doctor's Best High Absorption Magnesium Glycinate Lysinate

Doctor's Best High Absorption Magnesium Glycinate Lysinate


– High Absorption Magnesium Glycinate:
High Absorption Magnesium uses a patented, organic, chelated delivery form of magnesium to optimize bioavailability and GI tolerance. It is not buffered and is more absorbable than magnesium oxide.

– Better Absorbability:
Magnesium Glycinate – 2.3x greater than magnesium carbonate, 3.6x greater than magnesium sulfate, 6.0x greater than magnesium oxide, Chelated magnesium is absorbed faster and at a higher rate than ionic salts. Helps promote high magnesium retention in the body. Better tolerated, minimizes laxative effect — even at therapeutic doses. TRAACS (The Real Amino Acid Chelate System), not a synthetic chelate. Water soluble.

– Magnesium Health Benefits:
An essential dietary mineral, magnesium plays many important roles in the body.

– Not All “Amino acid chelates” are True Chelates :
High Absorption Magnesium is made with Albion minerals TRAACS, 100% not buffered. Albion unique chelated mineral, scientific process turns elemental minerals form into an absorbed nutrient that’s gentle on your stomach with no laxative effects.

Best High Absorption Magenesium Glycinate Lysinate also come in various other form:
Doctor’s Best High Absorption Magnesium Powder > Check on Amazon

4.6 out of 5 – more than 49,000 global ratings

Doctor’s Best Magnesium Glycinate Lysinate Reviews
My oncologist recommended this type of magnesium to aid my sleep. While it is just okay for that I did see a marked improvement in my bone density scan. I take 2 pills each night before bed. This was the 1st time in 10 years that my bones have gained density instead of continuing to lose density. For that reason alone this is worth taking as I will not do prescription drugs at all. This is a much better alternative.

C. Boron for Osteoporosis Prevention

Boron has been included in nutritional supplements or natural remedies designed to improve bone and joint health. Boron deficiency has been shown to impair brain function, inflammatory regulation, and immune response, and to increase the risk of some cancers.

According to some articles, any person who consumes a diet low in fruits and vegetables, is at risk for or has osteopenia or osteoporosis should consider taking boron supplements of 3 mg/d.

6. Life Extension Boron 3mg with Vitamin B2

Life Extension Boron 3mg with Vitamin B2

- Three Forms of Boron
Why take just one form of Boron? This tri boron complex is made with 3 forms of Boron: Boron Glycinate, Boron Citrate, and Boron Aspartate. Non-GMO and Vegetarian

- Boron Benefits
Supports healthy bone growth & mineralization. Supports optimal immune function

- Enhanced with Vitamin B2
This Tri-Boron supplement from LifeExtension contains 3mg of Boron for women and men. 180 Capsules per bottle.

4.5 out of 5 - more than 3,400 global ratings

Boron is important particularly for women, but many are mixed up with other things. I liked this one: it is pure and effective to maintain strong bones but one needs to be exposed to the sun for D3 and eat some kind of calcium (such as sesame seeds) in other words boron is complementary for the strength of the bones and this one is one of the best. I recommend this one. It was good for me.

7. Swanson Triple Boron Complex 3mg (Citrate, Aspartate & Glycinate)

Swanson Triple Boron Complex 3mg (Citrate, Aspartate & Glycinate)


- Bone & Joint Health Support
Swanson's premium triple boron complex promotes calcium absorption into your bones, which helps them stay strong and healthy as you age. These powerful nutrients may also support memory, focus, and overall brain function.

- Powerfully Pure
Our natural health supplement is a powerful blend of time-honored ingredients, delivering 3mg boron per capsule. Our formula is specially created for safe and effective wellness support.

- Dosage Instructions
Our wellness supplements offer everyday solutions for an enhanced mind, body, and home using only the purest ingredients. For best results, take one capsule per day with water.

- Our Quality Commitment
For nearly 50 years, swanson has delivered science-backed health products worldwide. Each wellness supplement is made in our gmp certified facilities, and our purity and potency testing includes independent third-party labs.

4.6 out of 5 - more than 1,850 global ratings

Swanson Triple Boron Complex Supplement Reviews
I bought this product looking for strength my bones, I'm asthmatic and the medicines that treat my asthma may me to lose calcium, steroids, I started taking one year ago this extra help supplement, and my doctor advised me take a test for my bone, and thanks God, they are normal... I recommend this medication as a strengthening of the bone...

D. Vitamin K for Osteoporosis Prevention

Several studies have shown that vitamin D, calcium, and recently vitamin K play an important role in the maintenance of optimal bone health, especially among older adults.

Several points of experimental evidence seem to outline that vitamin K play an important role for bone health. And a vitamin K deficiency is associated with several diseases, including osteoporosis and vascular calcification. (Source)

Adequate Intakes (AIs) for Vitamin K
19+ years : Male 120 mcg, Female 90 mcg

8. Life Extension Super K – Vitamin K1 and Two Forms of K2

- Strong Bones, Healthy Heart 
This formula provides a potent dose of 2600 mcg of Vitamin K from both K1 and 2 forms of K2. Vitamin K helps maintain your body’s calcium balance, which affects everything from arterial health to bone density health. But it’s hard to get sufficient vitamin K from food

- Vitamin K, Hold the Cheese
Vitamin K2 comes from meat, eggs and cheeses. Some people avoid these foods for health reasons, which can make it hard to get enough. And there’s more than one kind of K2 as well: this supplement has MK-4 and MK-7. MK-4 absorbs fast, while MK-7 stays active in your body much longer. Combining the two gives you the benefits of both!

- Ingredients Matter 
Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are Non-GMO, gluten-free, and Manufactured in the USA—and a Certificate of Analysis is available for every product we produce

4.7 out of 5 - more than 2,800 global ratings

From my wife Sarah: I take vitamin K to help my body process calcium and as a way to avoid a build up of calcium in the arteries. I'm very happy with the Life Extension brand. They make good quality items with a nice concentration of the K in the proper forms. This product is gluten and dairy free last I checked, which is great.

Be aware that vitamin K is used to help the body to clot blood, and if you're taking a blood thinner it can reduce the effectiveness. Vitamin K deficiency on the other hand can cause excessive bleeding and reduced bone density.

9. Nordic Naturals Vitamin D3 1000IU + K2 45mcg Gummies

Nordic Naturals Vitamin D3 1000IU + K2 45mcg Gummies

- Why Vitamin D3 + K2 
The combination of vitamin D3 and vitamin K2 provides superior support for the health and maintenance of normal bones, facilitates calcium & phosphorus balance in the blood, and promotes healthy muscle function.

- Delicious and Convenient
Our vegetarian, gelatin-free Vitamin D3 + K2 Gummies for adults are a great-tasting, convenient way to get a healthy dose of these important nutrients. They provide 1000 IU vitamin D3 + 45 mcg vitamin K2.

- Better Absorption
Vitamin D3 (cholecalciferol) is the natural, most easily absorbed & utilized form of vitamin D. Vitamin K2 as menaquinone-7 (MK7) is the most bioactive & bioavailable form of vitamin K. This product has a great pomegranate taste.

- Purity Guaranteed
Everything we make is third-party tested, surpassing the strictest international standards for purity & freshness. This product is non-GMO, gluten & dairy free, and contains no artificially derived colors or flavors.

- Ethical Innovation
Nordic Naturals has always been at the forefront of sustainable & ethical practices in the natural products industry. Through science & innovation, we are committed to delivering safe, effective nutrients for optimal wellness.

4.7 out of 5 - more than 1,800 global ratings

I take these in hopes that they will help prevent artery disease. I also give these to my daughter for healthy bone health. This is the only brand of gummy vitamin that I continually buy for my family since they are vegan and we do not use pork/porcine gelatin. These taste great, although they are covered in sugar it makes giving these to my daughter each day like a treat rather than a chore. Overall we are very happy with these vitamins!

E. Soy Isoflavones for Osteoporosis Prevention

Soy isoflavones are compounds found in soy and other plants (polyphenols). They have reportedly been found to have a wide range of physiological properties, including antitumor, anti-menopausal (female) osteoporosis, and anti-aging.

According to a study, soy isoflavones may help prevent osteoporosis-related bone loss in any weight status or treatment duration. They increase bone mineral density in normal weight subjects and diminish bone resorption in overweight/obese individuals.

10. Natrol Soy Isoflavones Capsules, Menopause Relief, 50mg

- Menopause Relief
Natrol soy isoflavones is a women’s natural dietary supplement designed to help provide menopause relief by naturally reducing hot flashes and night sweats. Note : package may vary

- Naturally Reduces Hot Flashes
Soy isoflavones are an exceptional source of natural estrogen that helps to reduce and relieve hot flashes. Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, yeast, artificial colors or flavors, added sugar or preservatives

- Can Relieve Night Sweats
When estrogen is introduced to the body, it naturally helps to reduce the potential of night sweats occurring.

- Supports Bone Health
Natrol soy isoflavones supports bone health and contains at least 35% of daidzein complemented with genistein and glycitein.

- Non-GMO Soy 
Natrol soy isoflavones uses only the highest-quality non-GMO soy.

4.4 out of 5 - more than 600 global ratings

It's what me doctor ordered to reduce /stabilize my osteopenia. One year check up shows that it is we working! No need for prescription drugs.

11. 21st Century Soy Isoflavones Veg Capsules, 60Count

Soy has been the topic of many new studies regarding heart & bone health in addition to supporting the needs of menopausal women. 21st Century uses only the highest concentration of Soy isoflavones extract (40%).
- it contains vegetarian formula.
- natural soy for female body, heart & bone health support
- no added sugar, salt, yeasy, preservatives or artificial flavors

4.4 out of 5 - more than 500 global ratings

Great to reduce wrinkles! Few weeks and noticeable changes. I’m taking extra doses now due to fracture to boost collagen production for healing my bone..

F. Multivitamin for Osteoporosis Prevention

12. NATURELO Bone Strength - Plant-Based Calcium, Magnesium, Potassium, Vitamin D3, Vitamin C, K2, Boron

- Plant-based Nutrients
Made with Plant-Based, Whole Food nutrients for healthy bone support, including Calcium and Magnesium from Marine Algae, Vitamin D3 from Lichen, and Vitamin C from Organic Acerola Cherries.

- Complete Formula
Includes 10 vitamins & minerals that work together to support healthy bone building and help maintain bone density,* including Vitamin D, K2, C, Zinc, Magnesium, Manganese, Potassium, Boron, and Silica.

- Healthy Calcium Absorption
Vitamin D3, Magnesium, and Vitamin K2 are crucial co-factors that help your body to absorb and use calcium properly, so that it goes into your bones rather than your arteries and soft tissues.*

- Powerful Benefits
Studies show that adequate calcium and vitamin D as part of a healthy diet, along with physical activity, supports healthy bone density later in life. Older women are particularly at risk for bone loss.

- Clean Label
This supplement does NOT Contain GMOs, Soy, Gluten, Yeast, Dairy, Eggs, Nuts, Caffeine, Coloring, Preservatives, or Flavoring. Free of Animal By-Products. Appropriate for Vegans and Vegetarians.

4.6 out of 5 - more than 7,500 global ratings

I have spent most of my 73 years of life with soft, papery fingernails, always assuming it was because I didn't drink milk. A couple of years ago, upon taking a bone density test, I was told that I have osteoporosis and osteopenia throughout most of my body. I wanted to take something natural to help my bones. 

Not long ago, I started taking Bone Strength. Before I even got through the first bottle, I noticed how hard and strong my nails were getting. I firmly believe that, after all these years, I have finally found a product that is (hopefully) increasing my bone mass inside my body as well. Thank you to NATURELO!

13. New Chapter Bone Strength Organic Plant Calcium with Vitamin K2 + D3 + Magnesium

- Bone Strength
Slim, easy-to-swallow tablets with slow & steady release. It helps protect against bone loss and promotes bone density & joint mobility

- Organic Calcium
USDA Organic plant-based calcium from sustainably harvested Red Marine Algae. USDA Organic, Non-GMO Project Verified, 100% Vegetarian, Kosher, Certified Gluten Free by NSF, Sustainably Harvested

- Formulated for Absorption
Expertly formulated with Vitamin D3 for better absorption, Vitamin K2 to direct calcium to bones (where you need it most), magnesium and 70 whole-food trace minerals

4.7 out of 5 - more than 4,500 global ratings

Highly reccomended by nutritionist. My sisters bone density test returned to normal after taking these for a year...

14. Jarrow Formulas BoneUp Three Per Day - Vitamin D3, Vitamin K2, Calcium, Magnesium, Boron, Vitamin C

Jarrow Formulas BoneUp Three Per Day - Vitamin D3, Vitamin K2, Calcium, Magnesium, Boron, Vitamin C

- Micronutrient Formula for Bone Health
BoneUp Three Per Day is a comprehensive micronutrient formula that provides StimuCal MicroCrystalline HydroxyApatite (MCHA) and micronutrients to support bone health, bone density, and skeletal nutrition

- Bone Density Support
StimuCal MCHA is a natural source of calcium shown to support bone mineral density better than calcium carbonate; StimuCal also provides bone proteins, including type I collagen, which has been shown to support bone health

- Convenient Capsules
BoneUp Three Per Day offers the same nutrients of regular BoneUp but in a 3-capsule formula; Take 1 capsule 3 times per day (for a total of 3) with meals to facilitate max absorption or as directed by a healthcare professional

- Superior Nutrition and Formulation
The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements; Our customers can be assured of purity, value, and potency

4.7 out of 5 - more than 3,020 global ratings

I only really take one of these a day, because it has some vitamin K, be careful if you are on blood thinners but other than that, my bone density scans are really good! I am a retired nutritional specialist and calcium hydroxyapatite is the most absorbable form.

15. BioSchwartz Bone Strength Supplement with Calcium + D3, K2, Magnesium, Boron

BioSchwartz Bone Strength Supplement with Calcium + D3, K2, Magnesium, Boron

- Comprehensive Bone Health Formula
BioSchwartz ultra pure bone strength features key bone building nutrients including Vitamin K2, Calcium and Vitamin D3 for bone support

- Optimal Absorption
BioSchwartz ultra pure bone strength includes magnesium to assist in calcium absorption, an essential mineral for bone health

- Purity Tested & Allergen Free
Each and every batch of BioSchwartz ultra pure bone strength are third party tested to guarantee high purity, potency, and quality. This formula has been manufactured without GMOS, soy, gluten, milk, egg, wheat, peanuts, or shellfish. They also don't include preservatives, artificial ingredients, fillers, chemicals or color additives

- Formulated by Professionals
Each one of BioSchwartz’s professional grade supplements is created by a team of highly experienced healthcare professionals in the USA following strict GMP guidelines to ensure the greatest benefits are achieved

4.5 out of 5 - more than 630 global ratings

I was just recently been diagnosed with osteoporosis. My doctor had recommended that I take a calcium supplement. Did some research and found this product. I was happy with the reviews and the ultra pure claim. It is a little to soon to see or feel any difference, but I am confident that it will help with my bone strength.


a. Calcium Food Sources

• Dairy foods
• Green leafy vegetables – such as curly kale, okra but not spinach (spinach does contain high levels of calcium but the body cannot digest it all)
• Bread and anything made with fortified flour
• Fish where you eat the bones – such as sardines and pilchards

b. Magnesium Food Sources

• Avocados.
• Seeds and nuts: Almonds, Cashews, Flaxseed, Peanuts, Pumpkin seeds.
• Fatty fish.
• Legumes: Black beans, Edamame, Lima bean.
• Fiber-rich whole grains: Quinoa, Shredded wheat.
• Fruits and berries: Papaya, Raspberries, Tomato, Cantaloupe, Strawberries and Watermelon.
• Leafy Greens: Spinach, Swiss chard, Turnip greens, Beet greens, Collard greens, Broccoli, Brussels sprouts, Kale, Bok Choy, Romaine lettuce.

c. Vitamin D Food Sources

Vitamin D3 is not naturally present in many foods. The flesh of fatty fish and fish liver oils are the finest sources. Cheese, beef liver, and egg yolks all contain smaller amounts.

d. Best Exercise for Osteoporosis

Related Articles


Popular posts from this blog

Zinc Gluconate vs Zinc Picolinate: What's the Difference?

Dr. Zelenko's Z-Stack Vitamin Cocktail: Review 2024

NAC vs NAD vs NR vs NMN vs Niacin: What Are the Differences?

18 Best Supplements to Reduce Cytokine Storm: Advanced Guide

10 Best NMN Supplements (2024 Review)

Phytonutrients, Polyphenols and Flavonoids 101: What You Need to Know (2024)

Best Anti Aging Supplements 2024: Unveiling the Science Behind Longevity Medicine (300+ Studies Analyzed)

PicoWay vs PicoSure vs PicoPlus vs PicoCare: What are the Differences?

Many Different Diets Shown to Be Effective for Autism Symptoms

Immune Support: Quercetin, Vitamin C, Zinc, Vitamin D3 (2023)