Best Sulforaphane (Broccoli) Supplements 2022

What is Sulforaphane?

broccoli sprout
Photo: CGissemann/

Sulforaphane is a natural plant compound obtained from cruciferous vegetables like broccoli, bok choy, and cabbage.

It is present in the inactive form glucoraphanin. When glucoraphanin interacts with myrosinase, a family of enzymes involved in the defense response of plants, sulforaphane is activated.

Only when a plant is damaged, myrosinase enzymes can be activated and released. Therefore, in order to release myrosinase and activate sulforaphane, cruciferous vegetables must be cut, chopped, or chewed.

Potential Health Benefits of Sulforaphane

Reduce the Risk of Cancer. Clinical studies have supported the chemopreventive effects of Sulforaphane (SFN) on carcinogenesis. SFN protects cells from environmental carcinogens and also induces growth arrest and/or apoptosis in various cancer cells.

For example, sulforaphane and its conjugate metabolite N-acetylcysteine was shown to limit the malignant progression of lung adenomas in A/J mice exposed to tobacco carcinogens. (Source)

Eliminates toxin. Sulforaphane is an active antioxidant. Antioxidants play a crucial role in maintaining good health because they may lessen or prevent the effects of free radicals. Free radical damage has been linked to numerous chronic health issues, including cardiovascular disease, cancer, and many more. 

Reduces inflammation. In addition to removing toxins from your body, sulforaphane also reduces inflammation.  Inflammation has been related to several types of cancer.

May boost heart health. In a rabbit model of chronic heart failure, treatment with SFN improved cardiac function and remodeling by inhibiting oxidative stress and inflammation. (Source)

Inhibited the Nociceptive Responses, Anxiety- and Depressive-Like Behaviors Associated With Neuropathic Pain. A study suggested that treatment with SFN might be an interesting approach for the management of persistent neuropathic pain and comorbidities associated. Moreover, it also diminished the anxiety- and depressive-like behaviors associated with persistent neuropathic pain.

Best Sulforaphane (Broccoli) Supplements 2022

1. Avmacol Extra Strength Sulforaphane Production System

Avmacol Extra Strength Sulforaphane Production System for Immune Support, 75 Tablets


Contains broccoli extracts glucoraphanin and myrosinase. Our trademarked Myrosimax enzyme ensures the presence of active myrosinase enzyme to support sulforaphane production. Includes Maitake mushroom extract to support your body’s natural detoxification process better than sulforaphane alone and to provide added immune support*

Sulforaphane promotes your body’s natural detoxification process for certain environmental threats found in the air you breathe, the food you eat, and the water you drink* Defense against oxidative stress and cell damage*

How To Take

Tablets may be swallowed whole or crushed for easier consumption

4.8 out of 5 - more than 300 global ratings

AMAZING! Has helped tremendously with my memory recall, retention, and motor skills. I’m 26 and felt like I had prealzheimers with Parkinson’s like tremors from a bad concussion 7 years ago. I’ve been taking this for a year now and it’s the only thing that I truly feel has healed my brain. I also haven’t gotten sick since taking it. Gotta love Sulforaphane!

2. Thorne Crucera Sulforaphane Glucosinolate (SGS) - Broccoli Seed Extract

When Thorne's Crucera-SGS is ingested and begins to break down in the gut, it releases sulforaphane, thereby activating the body's natural detoxification and antioxidant enzymes, and providing protection for several days to cells from free radical damage.*

Thorne products contain ingredients from the purest sources worldwide. Flavors, colors, preservatives, and sweeteners are derived from natural sources. Our products never contain gluten, Genetically Modified Organisms (known as GMOs), artificial preservatives, stearates, wheat, rye, barley, eggs, or nuts. This product does not contain dairy, soy, corn, yeast, sugar, or magnesium stearate.

Its the best source to fight the inflammatory and its great supplement for post cancer treatments.

3. SMNutrition Sulforaphane Supplement

Sulforaphane Supplement 19mg Real Stabilized Sulforaphane | 405mg Complex | 125mg of Glucoraphanin & Myrosinase | from Broccoli Sprouts & Seed Extract | Antioxidant, Detoxification, Cellular Health

- 18mg OF Myrosinase Per Serving
Your body can’t make sulforaphane in the gut without the enzyme myrosinase. Each 2-capsule serving contains at least 18MG of myrosinase from BroccoRaphanin and Organic Mustard Seed, making this a more powerful sulforaphane supplement.

- The Real Deal
Levels of Sulforaphane can vary between strands of broccoli. That’s why we use BroccoRaphanin Broccoli Seed Extract and BroccoPhane, which yield a high amount of real, stabilized sulforaphane powder -- 19MG per serving. Don’t be fooled by sellers who use “MCG” instead of “MG.” 1000mcg = 1mg.

- The SMNutrition Difference
We are one of the few brands that conduct Third-Party Testing to verify that our formula has an Active Potency of 19MG of Sulforaphane per serving, and a minimum of 18MG of Myrosinase per serving. Activated Sulforaphane is Certified Gluten-Free, Non-GMO, Vegetarian, HALAL Certified, and formulated without the top 8 allergens. Enjoy a 30-day supply in every bottle!

- More Than an Antioxidant
Sulforaphane stimulates the release of NRF2, which then supports over 200 genes. These genes prompt cells to create their own antioxidants to reduce oxidative stress, making Sulforaphane more than an antioxidant supplement.*

- Cellular Health Supplement 
Many of the 200+ genes supported by NRF2 also independently support the body’s detox responses. A high quality cruciferous extract supplement like Activated Sulforaphane is the easiest way to get sulforaphane every day.

4.6 out of 5 - more than 750 global ratings

Everyone is under stress. We must start supplementing, if possible, to protect ourselves from the results of high stress. This is not the world we use to live in, or often do not recognize. Research is necessary for protecting you and everyone you love! Sulforaphane with myrosinase and mustard seed extract is a great start! sulforaphane needs to be recognized for all it's glory. For mental health problems and cancer to start. Dr. Rhonda Patrick will tell you all about it better than I on utube. I love her! Beautiful and smart!! She will educate you fast.

4. Osasuna Liposomal Sulforaphane with Myrosinase

- Advcanced Liposomal Delivery for Maximum Absorption
Unlike regular sulforaphane supplement, Osasuna liposomal sulforaphane offers the Maximum Absorbability. Liposomal encapsulation forms a protective shield around sulforaphane that does not come into contact with the stomach acid to achieve Highest Bioavailability.

- Long-Lasting Antioxidant Formula, 450mg Per Dose
150mg sulforaphane + 300mg glucoraphanin from Broccoli Seed Extract. Sulforaphane in cruciferous vegetables occurs in a stored, inactive form as glucoraphanin. Glucoraphanin (Precursor of Sulforaphane) is converted to sulforaphane's active form by the enzyme myrosinase. The powerful combination dramatically enhances the potency and makes a long-lasting effect.

- Optimized With Proprietary Sulforaphan Boost Blend
Your body can’t make sulforaphane in the gut without the myrosinase enzyme. Each serving contains 250MG of Organic Mustard Seed, Myrosinase Enzyme, Maitake Mushroom Extract. The Myrosinase and Mustard Seed aid in activating the bioavailability of Sulforaphane. Maitake Mushroom Extract works synergistically with sulforaphane for anti-inflammatory.

- Natural Detox & Antioxidant
NRF2 activation affects the expression of over 200 genes including antioxidant, anti-inflammatory and detoxification genes. Sulforaphane is the most potent naturally occurring activator of the NRF 2 pathway, which is the strongest defense against oxidative and aging.

I am an individual who has a pre-cancer blood disorder called MGUS. There are studies that indicate that the compound in this supplement has the ability to kill MM cells. Only time will tell, but these are easy to swallow and I have no stomach issues from them.

5. Source Naturals Broccoli Sprout Extract

The nutrients from broccoli have been shown to support liver health, helping the liver do its important work. Source Naturals Broccoli Sprouts Extract provides 2,000 mcg of sulforaphane per serving - that's up to 5 times more than an average serving of fresh broccoli.*

- this formula is available in bottle sizes of 30, 60, and 120 tablets
- the suggested use is to take 2 tablets 1 to 2 times a day.
- contains calcium and sprouted broccoli extract blend.

4.5 out of 5 - more than 540 global ratings

I bought this supplement for my wife and myself because research has shown substantial health benefits from Sulforaphane (broccoli sprouts extract), lowered blood sugar is just one of those. We've been taking the supplement for over a month with good effect, I think. One tablet a day is sufficient based on my research.

6. BrocElite Plus Broccoli Supplement with Stabilized Sulforaphane Extract

- Broccoli Supplement To Help You Thrive
While balanced meals are good for you, their nutrient content won't do if you want to give your mind & body the support it needs. With BrocElite, you're getting optimized nourishment straight from the source. These are total wellness formula capsules that contain the only naturally derived stabilized sulforaphane molecule to support immunity, cognitive, heart and neuro health.

- Heart Health, Brain Function & Joint Support
Poor body inflammatory response is one of the major causes of heart and brain problems. Combat it with the BrocElite vitamins and minerals supplements that are brimming with anti inflammatory properties--activates a defense system to help lessen swelling and you can enjoy life more

- Powerful Ingredients Derived from Nature
Our stabilized sulforaphane broccoli extract supplement is made only from ingredients that will do good for you. BrocElite does not contain any Glyphosate residue, gluten, GMO, and is made without fillers, artificial colors, flavoring, sweeteners, preservatives, sugar, starch, corn, soy, egg, lactose, wheat, yeast, fish, or sodium.

- Two Daily Capsules for Optimized Results
We recommend taking one BrocElite capsule in the morning and one at night, with food or an empty stomach. But because we know that not everybody is built the same, and not everyone will experience a dramatic improvement in symptoms, we'll provide a 30-day return on your first bottle, no questions asked. So we can make things right for you, in case you are not satisfied.

BrocElite Plus Broccoli Supplement Reviews
I have RA and treat it naturally. I recently found out that I had h. Pylori and thought I'd try this as broccoli sprouts are good for that. I had no idea it would help my RA! Within 3 days of taking this supplement my hips no longer hurt (that's the source of most of my RA pain). That was a great added benefit I wasn't expecting!


a. How to Get the Most Sulforaphane From Broccoli?

Sulforaphane levels are higher in raw vegetables.

study showed that consumption of raw broccoli results in faster absorption, higher bioavailability, and higher peak plasma amounts of sulforaphane, compared to cooked broccoli. 

The best technique to maximize sulforaphane levels when cooking may be to steam veggies for one to three minutes. As cooking vegetables beyond this temperature causes the loss of glucosinolates like glucoraphanin, it is advisable to keep the temperature below 284 °F (140 °C).

Therefore, it is advised to avoid boiling or microwaving cruciferous veggies. Instead, consume them raw or lightly steamed in order to get their maximum sulforaphane content.

b. Which supplements are reliable sources of sulforaphane?


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