Best Fisetin Supplements 2024

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Fisetin is a naturally occurring flavonoid, a type of plant pigment found in various fruits and vegetables such as strawberries, apples, grapes, onions, and cucumbers. It is known for its antioxidant properties and potential health benefits.


Fisetin Supplement Benefits

Antioxidant Properties
Fisetin acts as an antioxidant, helping to neutralize harmful free radicals in the body, which may contribute to aging and various diseases.

Anti-inflammatory Effects: 
Fisetin has anti-inflammatory properties. According to a research, fisetin decreases the expression and secretion of inflammatory cytokines in lipopolysaccharide (LPS)-treated cells. Additionally, it facilitates autophagosome-lysosome fusion and degradation, which is associated with reducing inflammation. These effects are mediated through the inhibition of the PI3K/AKT/mTOR signaling pathway.

Brain Health
Fisetin may help decrease neurotoxicity and neuro-inflammation, both of which are harmful processes that can contribute to neurological disorders. Moreover, Fisetin helps maintain the balance of redox profiles (oxidation-reduction reactions) and supports mitochondrial function, which is crucial for cellular energy production and overall brain health. (S)

Heart Health
According to some researches, fisetin has the potential to protect against ischemic damage following MI (Myocardial infarction and overcome IRI (ischemia reperfusion injury) by enhancing cell viability, inhibiting apoptosis and ROS generation, protecting DNA, and promoting cardiac regeneration. Therefore, fisetin could be considered beneficial for heart health, particularly in the context of ischemic heart disease.

Remember, while fisetin supplements may offer potential health benefits, it's essential to maintain a balanced diet and lifestyle for overall well-being. Always consult with a healthcare professional before starting any new supplement regimen.



Best Fisetin Supplements

1. Doctor's Best Fisetin with Novusetin

Doctor's Best Fisetin with Novusetin

BUY ON AMAZON

Doctor’s Best Fisetin with Novusetin contains a naturally sourced flavonol that displays positive effects on brain cells and cognitive function pathways in preclinical research. Fisetin is a bioflavonaid antioxidant that can help maintain glutathione levels and mitochondrial function in the presence of oxidative stress.

*These statements have not been evaluated by the Food and Drug Administration. This product in not intended to diagnose, treat, cure or prevent any disease.

Ingredients
Fiseten (as Novusetin) (from Rhus succedanea stem) 100mg, Cellulose, modified cellulose (vegetarian capsule).

Ratings: 4.4 out of 5 1,151 global ratings

Doctor's Best Fisetin with Novusetin Reviews
The marketing for this product lists "helps support antioxidant activity, cognitive function, and memory". I take it along with a bunch of other "brain health" supplements. There are also interesting NIH studies on the various other health benefits this flavonoid may offer.



2. Double Wood Supplements Fisetin

Double Wood Supplements Fisetin


Double Wood's Fisetin is Vegan, Non-Gmo, and Gluten Free. Fisetin is classified as a "Senolyitc Agent" meaning it supports your body's ability to clear away damaged or potentially harmful cells.It helps support healthy aging by promoting cell efficiency and help to support organ health, brain health, and mood*

Ingredients
Fisetin 100mg, Other Ingredients: Veggie Capsules (Hypromellose), rice flour, cellulose

Double Wood Fisetin Supplements Reviews
This arrived quickly. It’s part of a larger protocol, so I can’t specifically narrow down its effectiveness, but I see improvement in cognitive function.



3. HUMANX Fisetin 500mg

HUMANX Fisetin 500mg


Fisetin Supports cellular protection from stress related damage, so cells function at full capacity. Fisetin helps the body produce glutathione, the most powerful antioxidant in the body.*
- Anti-aging Support*
- Brain Support*

Ingredients
98% Pure Fisetin

HUMANX Fisetin Supplements Reviews
After doing some exploration about different antioxidants and anti inflammatories, I came across Fisetin. I suspect my husband’s extreme fatigue is from damage to his mitochondria so I decided to do an experiment. I added this supplement to his daily intake without telling him. After around a week, I’ve noticed he’s doing more activity and seems more energized and seems to be in a little less pain!!  So little has helped him. 

I’m over the moon that this seems to be making a difference so quickly.



4. Life Extension Bio-Fisetin

Life Extension Bio-Fisetin


Life Extension Bio-Fisetin combined fisetin with galactomannan fibers from fenugreek seeds to help preserve fisetin through your digestive system, making it up to 25 times more bioavailable than standard fisetin.

Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every product we produce.

Ingredients
Proprietary Blend: 44.5 mg Providing 18% fisetin (8 mg) [from wax tree extract (stem)], 35% galactomannans (15 mg) [from fenugreek (seed)] Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate, soluble fiber, sunflower lecithin.

Life Extension Bio-Fisetin Reviews
Within a few days I noticed that I was able to recall names of things and places much quicker then I used to if at all before. I started Off with one tablet I mean capsule a day and after a few weeks I started taking two which gave me the best results



5. Toniiq Ultra High Purity Fisetin 500mg

Toniiq Ultra High Purity Fisetin 500mg


Toniiq Ultra High Purity Fisetin 500mg was designed to be one of the purest and bioavailable fisetin supplements on the market. Our fisetin capsules are higly purified at 98%+, ensuring that you receive the maximum benefits from this incredibly potent senolytic nutrient.

Unlike many other fisetin supplements, our formula includes MCT oil to aid absorption and bioavailability. By combining fisetin with MCT oil, we've created a unique and highly effective fisetin 500mg supplement that your body can utilize more efficiently.

Toniiq products are produced in a GMP-certified and NSF-approved state-of-the-art manufacturing facility right here in the USA.

Ingredients
Fisetin, MCT Oil Powder



Who Should Avoid Fisetin Supplements?

  • Pregnant or Breastfeeding Women: As with any supplement, pregnant or breastfeeding women should consult with their healthcare provider before taking fisetin supplements to ensure safety for both mother and baby.
  • People with Medical Conditions: Individuals with certain medical conditions or those taking medications should consult their healthcare provider before starting fisetin supplements, as fisetin could interact with certain medications or exacerbate certain health conditions.


FAQs

a. What is the Recommended Dosage of Fisetin?

The optimal dosage of fisetin supplements has not been established, and it may vary depending on individual health needs. It's advisable to follow the dosage instructions provided by the manufacturer or consult with a healthcare professional for personalized guidance.

b. Fisetin Side Effects

Fisetin is generally considered safe when taken in appropriate doses, but some individuals may experience mild side effects such as digestive discomfort or allergic reactions. It's essential to discontinue use and consult a healthcare provider if any adverse reactions occur.


c. Is Fisetin Suitable for Vegans and Vegetarians?

Yes, fisetin is derived from plant sources and is suitable for vegans and vegetarians.



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