12 Best Quercetin Supplements and Reviews of 2022
Quercetin is a type of flavonoid present in many fruits, vegetables, and
grains. It’s one of the most abundant antioxidants in the diet and plays an
important role in helping your body combat free radical damage, which is
linked to chronic diseases.
In addition, its antioxidant properties may help reduce inflammation, allergy symptoms, and blood pressure.
Some doctors are also advocating its use against SARS-CoV-2 (COVID-19), in combination with vitamin C, noting that Quercetin and Vitamin C have synergistic effects. Quercetin also acts as a zinc ionophore (PubMed 2014), the same mechanism of action that hydroxychloroquine has via helping zinc pass the cell wall where it might halt viral replication.
There are many quercetin supplement brands available out there. Which one should you buy? Why do we provide so many options below? You may have your own set of purchasing criteria and it's likely to be different for different individuals.Although there are many quercetin supplement customer reviews on many online sites, we have curated some of the helpful ones below. Check out below the best quercetin supplements available online.
Best Quercetin Supplements 2022
1. Thorne Research Quercenase
- Promising Effects of 3-Month Period of Quercetin Phytosome® Supplementation in the Prevention of Symptomatic COVID-19 Disease in Healthcare Workers: A Pilot Study (Life, Jan 2022)
- A Randomised Controlled Trial of 152 outpatients with COVID-19 in Pakistan, 76 treated with quercetin phytosome, showed lower mortality, ICU admission, and hospitalization with treatment (International Journal of General Medicine, May 2021)
BestReviews.com: A potent, science backed formulation by a brand known for quality that is made with the purest ingredients for maximum efficacy. However, it is relatively pricier than many similar products on the market.
Amazon Best Sellers: 4.8 out of 5 overall rating with more than 200 customer reviews.
Our Take: If you are looking to buy from a reputable brand, this would be your choice.
2. MoxyVites Quercetin 500mg with Bromelain Supplement, Bioactive Phytosome Complex
Quercetin is a zinc ionophore. Meaning it transports zinc into the cells.
It is known that zinc will slow down the replication of coronavirus through inhibition of enzyme RNA dependent RNA polymerase (PubMed 2010). The COVID-19 virus is a single stranded RNA (RiboNucleicAcid) virus and requires the RNA polymerase to replicate.
Vitamin C and quercetin co-administration exerts a synergistic antiviral action due to overlapping antiviral and immunomodulatory properties and the capacity of ascorbate to recycle quercetin, increasing its efficacy.
- What is the Zelenko protocol? The Zelenko COVID-19 Protocol was developed by Dr Vladimir Zelenko. A retrospective study analyzing Dr Zelenko's patient data was accepted for publication in the International Journal of Antimicrobial Agents after a rigorous peer review process. The study finds that early intervention and treatment of high-risk patients with COVID-19 resulted in significantly fewer hospitalizations and deaths. The treatment consisting of zinc, low-dose hydroxychloroquine (HCQ), and azithromycin, is also referred to as "The Zelenko Protocol." Dr Zelenko has since updated his protocols to incorporate new evidence.
4. Natural Factors Bioactive Quercetin
Dosage of quercetin is somewhat low (as compared to other brands) in each capsule. However, Natural Factors claims the quercetin is more bioavailable, which means your body gets a strong dose regardless. Each capsule contains 167 mg of EMIQ and 50 mg of vitamin C. Natural Factors claims their formula will provide year-round protection while supporting a healthy inflammatory response and maintaining good sinus and upper respiratory function.
5. Amazing Formulas - Quercetin 500 Mg (Best for Vegetarians)
6. Doctor's Best Quercetin Bromelain
- Non-GMO, Vegan, Gluten Free, Soy Free
- 180 Veggie Caps
Bromelain 3000 GDU per capsule, has 500 Mg of Quercetin with 250 Mg
Bromelain for a Serving size of 2 Capsules
- Quercetin and Bromelain
enhances each other's antioxidant and anti-inflammatory potential.
Quercetin is a bioflavonoid that has potent antioxidants while bromelain
works as protein-digesting enzyme. Bromelain helps increase your body’s
absorption and use of Quercetin.
- Helps support immune health, heart
health, joint comfort, healthy digestions, respiratory health and
- Quercetin helps ensure appropriate immune
response, inhibits formation of free radicals and promotes circulatory
health in part by supporting the integrity of small blood vessels.
i have sleep apnea and have TO sit up in a recliner to sleep because i
can not use a CPAP. QUERCETIN CLEARS MY SINUS SO BOTH NOSTRILS ARE OPENED
WITH OUT ANY NEGATIVE PHARMCEUUTICAL DRUG SIDE EFFECTS . i now sleep lying
flat. thank you drs best. you formula.
Ratings: 4.7 out of 5 - more than 2,000 global ratings
- 180 Veggie Caps
- Bromelain 3000 GDU per capsule, has 500 Mg of Quercetin with 250 Mg Bromelain for a Serving size of 2 Capsules
- Quercetin and Bromelain enhances each other's antioxidant and anti-inflammatory potential. Quercetin is a bioflavonoid that has potent antioxidants while bromelain works as protein-digesting enzyme. Bromelain helps increase your body’s absorption and use of Quercetin.
- Helps support immune health, heart health, joint comfort, healthy digestions, respiratory health and inflammatory response.
- Quercetin helps ensure appropriate immune response, inhibits formation of free radicals and promotes circulatory health in part by supporting the integrity of small blood vessels.
7. BlueBonnet Super Quercetin
8. Forest Leaf Quercetin, Bromelain, Stinging Nettle, Vitamin C
9. Vitaraw Quercetin, Zinc, Bromelain, Vitamin C, Vitamin D3
10. Kappa Nutrition Immune C Plus
11. Mt. Angel Vitamins - Quercetin Nettle +
Buy on Amazon
- Natural Supplement for Sinus and Nasal Health, Seasonal Discomfort
and Healthy Histamine Levels
- 90 Vegetarian Tablets
- Contains Quercetin, which inhibits the manufacture and release of
- Stinging Nettle Leaf contains a large amount of Vitamins A, C, and
E. These vitamins are associated with both antioxidant and immune
system modulating activities
- REDUCES HISTAMINE PRODUCTION: Bromelain contains properties which
act as an Anti-Inflammatory and reduces swelling and breaks up
large, negatively charged proteins which attract fluid such as
histamine and bradykinin.
- BUILDS UP IMMUNITY: Contains Pantothenic acid, which is important
for the production of various immune system cells.
- MANUFACTURED IN THE USA in a FDA and UL NPA GMP Certified
- Raw ingredients and finished products are TESTED to confirm
identity and potency and to screen for impurities: heavy metals,
insecticides, and microbes.
Mt. Angel Quercetin Nettle was recommended to me about 5 years ago
by a nutritionist. My husband was suffering from sinus headaches. I
am not saying this will work for everyone but for him it is amazing!
His sinus headaches disappear about 15-20 minutes after taking 2
tablets. I have taken them occasionally with the same results. Love
Ratings: 4.5 out of 5 - 151 global ratings
12. Vimerson Health Quercetin Curcumin Bromelain (Best Quercetin
Vimerson Health's Turmeric Quercetin Bromelain supports muscle and
joint health* and supports the immune system* with this perfectly
combined daily multivitamin and mineral supplement; It also provides
antioxidant support and balanced inflammatory response;* The
antioxidant properties of this blend help the body in its ability to
neutralize free radicals*; These cause oxidative stress which
contributes to many imbalances in the body such as allergies.
Match made in heaven
This superb concoction of plants, herbs, and nurtrients combine in
perfect harmony to support each other, and enhance their benefits in
the body; The antioxidant properties of this blend help to soak up
free radicals; These cause oxidative stress which contributes to
aging, therefore this blend helps slow down the signs of aging and
heart health*; It is also known for relieving allergy symptoms *
The combination of Quercetin and bromelain along with turmeric,
provide a powerful immune support* and help balance the body’s
Our promise to you
Each batch we produce is packed with love and real ingredients for
real results*; Vimerson Health’s Turmeric Bromelain is formulated
safely and gently with no dangerous extraction processes or harsh
chemicals*; It is made NATURAL and contains zero soy, sugar, GMOs,
gluten, and dairy; You're getting more goodness per capsule than
anyone else*; Our Turmeric Bromelain provides you with the immune
support you require to be happy*
Vegan, gluten free, soy free, non-GMO
This, and all our products, are manufactured in the USA, meeting GMP
standards; Here at Vimerson Health we select only the highest quality
herbs, minerals and vitamins for optimal potency and efficacy; Our
standards of testing surpass any others on the market, ensuring that
only the best result is delivered to you; Our advanced formula is
suitable for men, women and seniors, and is lovingly compacted in
veggie easy-to-swallow capsules.
Ratings: 4.7 out of 5 - more than 2,800 global ratings.
Benefits of Quercetin SupplementsQuercetin is a bioflavonoid found in certain fruits, vegetables, and grains. Bioflavonoids like quercetin provide benefits by working as antioxidants.
You may already get a small amount of quercetin in your normal diet: quercetin is found in onions, kale, tomatoes, broccoli, asparagus, berries, red wine, citrus fruits, cherries, and tea. Many people also take quercetin in supplement form.
In fact, it’s estimated that the average person consumes about 10 to 100 mg of quercetin per day through a normal diet. Quercetin is one of the most abundant flavonoids in the human diet.
Quercetin is a pigment that belongs to a group of plant compounds called flavonoids (also known as bioflavonoids). Flavonoids are naturally present in fruits, grains, teas, and wine. Researchers have linked flavonoids to a variety of benefits, including a reduced risk of heart disease, cancer, and degenerative brain disorders.
What does science have to say about quercetin? Can quercetin really fight inflammation and reduce the risk of disease? Let’s dive into the science behind quercetin.
Quercetin has been shown to reduce inflammation in multiple studies. In this 8 week study involving 50 women with rheumatoid arthritis, participants took 500mg of quercetin per day or a placebo. The quercetin group reported less early morning stiffness, morning pain, and after-activity pain.
Early studies on quercetin and inflammation are promising, although more large scale human studies need to be performed to verify these benefits.
There’s evidence that quercetin reduces allergy symptoms. Researchers believe quercetin’s anti-inflammatory effects may relieve allergy symptoms.
This study published in Molecules in 2016, for example, found that quercetin could be effective for treating the anaphylactic (allergic) reaction in someone with peanut allergies. A similar study from 2006 concluded that quercetin was a “safe, natural therapy that may be used as primary therapy or in conjunction with conventional methods” for blocking allergies.
It’s possible that quercetin has the same anti-allergy effect in humans, although more research needs to be done.
There’s also some evidence that quercetin has cancer-fighting properties. Researchers believe quercetin can fight cancer cells with its powerful antioxidant properties.
In 2015, researchers reviewed available test tube and animal studies on quercetin and prostate cancer. After reviewing available evidence, researchers found that quercetin suppressed cell growth and induced cell death in prostate cancer cells.
This study published in 2017 in Oncology Reports took things a step further, finding that quercetin induced cancer cell death in nine types of cancer, including prostate cancer, colon cancer, and breast caner.
In another 2017 study, researchers gave quercetin to mice with tumors. Researchers found that mice in the quercetin-treated group showed delayed tumor growth, no significant changes in daily behavior, significantly better survival ratings, and increased rates of cell death.
Quercetin may also target bladder cancer. In 2016, researchers published a landmark study in the American Journal of Cancer Research. Researchers analyzed quercetin’s effect on cancer cells in a test tube. They concluded, “We are the first to show that quercetin displays potent inhibition on bladder cancer cells via activation of AMPK pathway.”
Early research on the cancer-fighting benefits of quercetin is promising, although more research needs to be performed to verify these effects in humans.
Other evidence suggests quercetin lowers your risk of chronic brain disorders, including Alzheimer’s and dementia.
In this study published in Neuropharmacology in 2015, researchers gave quercetin to mice with Alzheimer’s, injecting them with quercetin every two days for three months. By the end of the study, the injections had reversed several markers of Alzheimer’s, and the mice performed much better on learning tests.
In a separate study published in 2018, researchers gave mice with Alzheimer’s a quercetin-rich diet. Researchers found the diet improved brain function in mice with early-middle stage Alzheimer’s, although it had no significant effect on middle-late stage Alzheimer’s.
You may have heard that coffee is linked to a reduced risk of Alzheimer’s. There’s certainly some research to back that claim up. However, recent research has suggested that quercetin (not caffeine) is the primary compound in coffee responsible for protective effects against Alzheimer’s.
Some people use quercetin to reduce blood pressure and improve other measurements of cardiovascular health. High blood pressure raises your risk of heart disease, which is the leading cause of death in the United States. Approximately 1 in 3 American adults have high blood pressure.
Research suggests that quercetin reduces blood pressure levels. In this study published in 2002, researchers found that quercetin exhibited vasodilator effects, widening blood vessels and reducing blood pressure.
Multiple studies on humans have suggested similar benefits. Researchers reviewed nine human studies involving 580 people. After reviewing available evidence, researchers found that taking more than 500 mg of quercetin supplement per day reduced systolic and diastolic blood pressure by 5.8mm Hg and 2.6 mm Hg, respectively. In other words, quercetin was shown to significantly improve blood pressure readings.
Some people take quercetin for its anti-aging effects. Antioxidants and anti-inflammatories – including quercetin – seem to have powerful anti-aging benefits. One study on young mice found that quercetin reduced mortality and extended lifespan. Another study from 2017 on human cells in test tubes found that quercetin reduced aging markers, with researchers concluding there was “anti-aging potential” for quercetin.
Others take quercetin supplements to improve endurance and exercise performance. This 2011 study reviewed 11 quercetin studies involving 254 human subjects and found that quercetin provided a statistically significant benefit in human endurance exercise capacity (VO2 max) and endurance exercise performance, although the effect “is between trivial and small”.
Finally, some diabetics take quercetin to help manage blood sugar. This study from 2019 found that taking 500mg of quercetin per day significantly reduced fasting plasma glucose (FPG) levels, suggesting that quercetin helped control fasting blood sugar. This study in 2019 found similar results, finding that quercetin lowered serum glucose levels at doses of 10, 25, and 50mg per kg.
Some suggest that quercetin could treat the COVID-19 coronavirus. Quercetin was shown to be effective against SARS, the Ebola virus, and the Zika virus. This 2019 study by researchers in Korea found that quercetin and other flavonoids may inhibit the proteolytic activity of SARS-CoV 3C-like protease, creating an antiviral effect. Research on the coronavirus and quercetin is ongoing, and it’s unclear if quercetin will have similar antiviral effects against COVID-19. To be clear, there’s no evidence suggesting that quercetin treats, prevents, or manages the COVID-19 coronavirus, although research is ongoing.
Quercetin DosageMost quercetin studies use a dosage of around 500 mg per day, although some studies use a dosage of 500mg taken twice per day.
Most supplements have a similar dosage, offering 500 mg to 1,200 mg of quercetin per serving.
In some studies, researchers have given participants up to 5,000mg of quercetin per day with no reported side effects.
Quercetin has poor bioavailability. You might take a 1,200mg quercetin supplement, but your body only absorbs a small percentage of it. That’s why many quercetin supplements contain vitamin C or bromelain, as some evidence suggests they boost absorption.
There’s also some evidence that quercetin has a synergistic effect when combined with other flavonoid supplements. That’s why some quercetin supplements contain resveratrol, catechins, genistein, and other flavonoids.
Quercetin Side EffectsQuercetin is generally recognized as safe. It’s found in many fruits and vegetables, and most people will experience no side effects when taking normal dosages of quercetin.
There have been few reported side effects for quercetin supplements.
In some studies, large doses of quercetin (over 1,000mg) were linked with headaches, digestive issues, and tingling sensations. However, these symptoms were mild and uncommon.
Quercetin from food sources is safe for pregnant and breastfeeding women to take. However, there’s limited research on quercetin supplements in pregnant or breastfeeding women.
There’s no evidence that quercetin interacts with any drugs in a significant way. However, you should talk to your doctor before taking quercetin, especially if you are taking antibiotics or blood pressure medication.
Frequently Asked Questions About QuercetinThis section will help to answer some of the most commonly asked questions about Quercetin.
Q: What are the best foods for quercetin?
A: Capers, peppers (yellow and green), onions (red and white), shallots, asparagus, cherries, tomatoes, red apples, red grapes, broccoli, kale, red leaf lettuce, cranberries, blueberries, raspberries, green tea, black tea, and coffee are all excellent foods for quercetin.
Q: Do you get enough quercetin in your daily diet?
A: The average person gets 10 to 100 mg of quercetin per day through normal dietary sources. This can vary greatly. Carefully track your diet over an extended period to figure out if you have a dietary deficiency of quercetin.
Q: How much quercetin should you take per day?
A: Researchers typically use a dose of 500 mg of quercetin per day in supplement form. Most quercetin supplements contain between 500 and 1200 mg of quercetin, although this can vary. Check out the nutritional label for your quercetin supplement to be sure.
Q: Does quercetin help allergies?
A: Many people take quercetin supplements to avoid allergy symptoms. There’s evidence that quercetin has powerful anti-allergy benefits, although more research needs to be done.
Q: Does quercetin fight cancer?
A: Early research in test tube and animal models shows that quercetin may have cancer-fighting properties. While these findings are promising, more large scale human studies need to be performed. Research is not definitive. Consult your physician before using any supplement to improve your cancer.
Q: Does quercetin reduce the risk of Alzheimer’s?
A: Studies show that quercetin may reduce the onset of Alzheimer’s, particularly in the early and middle stages of the condition. However, studies have mostly been performed on mice and test tubes – not in humans.
Q: What are other names for quercetin?
A: Quercetin goes by a number of different names. You might see quercetin supplements labeled as bioflavonoid concentrate, bioflavonoid extract, or citrus bioflavonoid, for example.
Q: Can quercetin help you recover after exercise?
A: Some studies show that quercetin boosts recovery after exercise. In some small studies, athletes taking quercetin after exercise had faster recovery than a control group. Researchers believe quercetin reduces oxidative stress and post-exercise inflammation, helping your body recover.
Q: What are the side effects of quercetin?
A: Most people experience no side effects from quercetin, and any side effects tend to be mild. Quercetin side effects include tingling and numbness, headache, and nausea. Your chance of experiencing side effects increases at higher dosages (over 1,000mg).
Q: Why do so many quercetin supplements contain bromelain?
A: Bromelain is a naturally occurring, protein-digesting enzyme found in the stem of the pineapple. Bromelain seems to boost the absorption of quercetin by inhibiting inflammatory chemicals called prostaglandins. Bromelain may also decrease inflammation on its own.
Q: What’s the difference between rutin or glycosidic quercetin?
A: Quercetin is found in two forms, including in rutin or glycosidic form. Quercetin glucosides, such as isoquercitrin and isoquercetin, seem to be much more bioavailable and more quickly absorbed than quercetin aglycone or quercetin glycosides, such as rutin (quercetin rutinoside).
Q: Can you overdose on quercetin?
A: In one study, researchers gave participants 2,000mg to 5,000mg of quercetin per day with no adverse effects or signs of toxicity reported. Generally, quercetin is safe to take even in high doses, although you may experience mild side effects like nausea, digestive issues, and headaches at high doses. Excessively high doses of quercetin could lead to kidney problems.
Q: How much quercetin should you take for hay fever?
A: Experts recommend taking 400mg of quercetin twice a day between meals for hay fever. Also consult your doctor to help provide a more comprehensive and effective treatment for hay fever.
Q: Can children take quercetin?
A: Most studies suggest that it’s safe to give quercetin to your child, although you should use only half the dose you'd use on an adult. Talk to your pediatrician before giving any quercetin to your child.
Q: How does quercetin manage allergy symptoms?
A: Studies have shown that quercetin stabilizes mast cells that release histamine. Histamine is the principal mediator of reactions to pollen and other allergies. This makes quercetin a natural antihistamine. Many people use quercetin to treat symptoms of hay fever, including runny nose, watering eyes, and itching.
Q: Can you take too much quercetin?
A: You should start with a quercetin dosage of around 500mg per day to assess your tolerance. However, researchers have given participants up to 5,000mg of quercetin per day with few reported side effects. Look for symptoms like upset stomach and diarrhea. Excessively high doses of quercetin could lead to kidney problems.
Q: Who should not take a quercetin supplement?
A: Quercetin appears safe for anyone to take when used in normal dosages. However, there’s limited research on how quercetin supplements affect women who are pregnant or breastfeeding. People with high blood pressure, or anyone taking blood pressure medication, may also want to take to their doctor before taking a quercetin supplement.
Q: Can you take a quercetin supplement with a pineapple allergy?
A: If you’re allergic to pineapples, you should avoid quercetin supplements with bromelain. Bromelain, an enzyme in pineapples, is added to quercetin supplements to boost bioavailability. Overuse of bromelain can create problems for consumers.
Q: Does quercetin work for anti-aging?
A: Several studies have examined the effect of quercetin on aging. Quercetin is rich with anti-inflammatories and antioxidants, which could make it a powerful anti-aging compound.
Q: Does quercetin help asthma?
A: Quercetin may help asthma by relaxing smooth muscles lining the airway, improving airway flow.
Q: What’s better – quercetin tablets, capsules, powders, or liquid?
A: Quercetin liquid claims to be more bioavailable than other sources of quercetin. You take the liquid sublingually (underneath your tongue). However, limited research shows quercetin capsules or powders are more effective, and all forms of quercetin are absorbed poorly by the body.
Q: Where does quercetin come from?
A: Most supplement companies use various plant or vegetable-based sources of quercetin. Check the label.
Q: Can you get citrus-free quercetin?
A: Some quercetin supplements are specifically marketed as citrus-free, making them ideal for those with citrus sensitivities. Read the label or official product website for your supplement to be sure that it is actually citrus-free.
Q: Does quercetin help with diabetes?
A: There’s some evidence that quercetin helps with diabetes, helping your body manage blood sugar levels during fasting. However, more research needs to be done to verify these benefits.
Q: Is quercetin non-GMO?
A: Quercetin supplements are generally labeled non-GMO. Check the label to verify your quercetin supplement is not made from genetically modified ingredients.
Final ThoughtsQuercetin is a bioflavonoid with potent antioxidant and anti-inflammatory effects. Many take quercetin supplements daily to support various body systems.
Some people take quercetin supplements for allergies. Others take it to boost the immune system. Others take quercetin for general anti-aging or health, immune support and wellness.
Early research on quercetin is promising, and new human studies are released every year validating certain quercetin benefits.