7 Best Antioxidant Supplement for Immune System 2022

Antioxidants play a crucial role in maintaining good health because they may lessen or prevent the effects of free radicals. Free radical damage has been linked to numerous chronic health issues, including cardiovascular and inflammatory disease, cataract, and cancer. Vitamins C and E, selenium, and carotenoids including beta-carotene, lycopene, lutein, and zeaxanthin are some examples of antioxidants. 

Role of Antioxidants in Immunity

Recent clinical trials have found that antioxidant supplementation can significantly improve certain immune responses. Specifically, supplementation with vitamins C, E, and A or beta-carotene increased the activation of cells involved in tumor immunity in the elderly. Supplementation with the antioxidant vitamins also protected immune responses in individuals exposed to certain environmental sources of free radicals.

Do We Need Antioxidant Supplements?

Fruits and vegetables are excellent sources of antioxidants. You can increase your blood levels of antioxidants by consuming a wide variety of foods. However, some people may not be able to get enough nutrients only from their diet which is why they take an antioxidant supplement.

Antioxidant supplements contain nutrients, phytonutrients, or bioactive antioxidants, or substances that neutralize free radicals. But if they are consumed in large doses, it may have the opposite effect.

For instance vitamin A. Vitamin A is important for fetal growth and development, but at high doses, vitamin A supplements can increase the risk of birth defects (Trusted Source, Trusted Source). Therefore, women who might be or are pregnant should not take high doses of vitamin A supplements (Source).

Beta-carotene, the precursor of vitamin A, is not shown to lead to birth defects. But since taking the supplement long-term is associated with cancer, pregnant women should consult with their physician before taking beta-carotene supplements (Trusted Source, Trusted Source).

As for Vitamin C, all the adverse effects, including digestive distress and kidney stones, appear to occur when people take it in mega doses greater than 2,000 mg (Trusted Source).

Best to consult your doctor to decide which antioxidant supplement is suitable for you.

Best Antioxidant Supplement for Immune System

1. Healths Harmony Super Antioxidant Supplement

Healths Harmony Super Antioxidant Supplement


- Maintain Health with Full Body Antioxidant Support
Crucial to good health, antioxidants help support a strong and healthy immune system. Loaded with superfood extracts like pomegranate, this supplement boosts energy, supports the immune system, and supports a healthy heart.

- Super Antioxidants for Radiant Skin
As the body’s largest organ, your skin needs some special TLC! With acai berry and vitamin e, our supplement helps promote healthy, radiant skin!

- Natural Antioxidants Supplement
We’re able to offer unmatched results because we utilize a blend of natural extracts and vitamins! With goji berry and vitamins A and C, our supplement delivers incredible effectiveness that your body will thank you for!

- Premium Quality
As with all Healths Harmony supplements, our antioxidant blend is American-made, using global ingredients, under strict GMP guidelines. With naturally potent ingredients like trans-resveratrol and Hawaiian noni, you’d be hard pressed to find anything better!

4.5 out of 5 - more than 1,050 global ratings

Super Antioxidant Supplement - Powerful Super Food Antioxidants Blend - Acai Berry, Goji Berry, Pomegranate is a great supplement to take anytime but especially during the COVID pandemic. It helps to support one's immune system.

2. NOW Supplements Super Antioxidants

NOW Supplements Super Antioxidants


- Phytoflavonoid Formula
Including green tea extract, milk thistle extract, turmeric root extract, quercetin, bromelain extract, rosemary, grape seed extract, ginkgo biloba extract, ginger root, hawthorn extract, cranberry powder, and bilberry extract.

- Vegan, Comprehensive Blend
Filled with herbal extracts and helps to maintain optimal health.*

- Classifications/Certifications
Vegan/vegetarian, quality GMP assured, soy free, sugar free, nut free, dairy free, egg free, corn free, low sodium, made without gluten

- GMP Quality Assured: 
NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).

4.6 out of 5 - more than 750 global ratings

I love these pills. I have witnessed on myself what others reviewers have said as far as their nails getting stronger and hair becoming thicker. When I run out and don't take these for a little while it becomes a noticeable difference in my mood, mental clarity, and energy level. These pills make me feel great and I have told others about them. Great product!

3. Purely Beneficial Resveratrol 1450

Purely Beneficial Resveratrol 1450


- 100% Pure & Natural Ingredients
Perfectly crafted with the exact amounts of ingredients for optimal nutritional value, and maximum benefits. No fillers, no artificial ingredients, no harmful preservatives, no inferior ingredients.

- High Potent Antioxidant
1450mg of the potent resveratrol blend made with: trans-resveratrol, green tea extract, grape seed extract, vitamin c, acai extract, pomegranate extract, blueberry extract, and more.

- Why Choose Purely Beneficial’s Resveratrol
Designed and formulated for Maximum effect and a wealth of benefits. Our facility is FDA Inspected, and maintains strict cGMP Standards, being made only here in the USA. We stand behind our products offering a 100% Money Back Satisfaction Guarantee.

4.6 out of 5 - more than 8,900 global ratings

I have been taking this reservatrol now for 2 years. In the past, I used to get the flu at least once a year, had bronchitis every September with horrible throat pain. Since taking this supplement, I have only had minor colds that lasts 1-2 days and my bronchitis in September is all but gone. I haven't had a sore throat in 2 years.... for me... this was a big deal!! 

The only other supplements I take is fish oil and a probiotic. I am truly amazed!! I can only speak for myself, but this supplement has really supported my immune system. I notice when I forget to take it, I start feeling tired and less energetic. It has good natural ingredients, so it doesn't hurt to try. This really works!!

4. 21st Century Ace Antioxidant Tablets

21st Century Ace Antioxidant Tablets


Nourishment from the complete group of antioxidants. Vitamins A, C, and E combined with the essential minerals selenium, zinc, copper, and manganese for a comprehensive antioxidant formula* No added yeast, preservatives, or artificial flavors, gluten-free.

As a dietary supplement, adults take one (1) tablet daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage. Individual results may vary.

4.7 out of 5 - more than 350 global ratings

Working well! More energy and able to make it through the day without feeling like death afterwards.

5. Solgar Advanced Antioxidant Formula

Solgar Advanced Antioxidant Formula


- Advanced Antioxidant Support
Solgar advanced antioxidant formula provides ingredients that promote antioxidant activity and provide antioxidant support to the cells of the body

- Zinc And Other Antioxidant-Rich Trace Minerals
This formula contains 10 mg of zinc, 91% of the recommended daily value; Zinc exerts antioxidant activity and can support a healthy immune system; Also includes selenium, copper, and manganese

- Vitamins A, C And E
Solgar advanced antioxidant formula features Vitamins A, C and E to help fight against destructive, cell damaging free radicals in the body

- Vegan, Gluten Free, And Dairy Free
Free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor and sweetener

- The Gold Standard
For over 70 years Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials

4.7 out of 5  - more than 300 global ratings

I feel much better, I've been taking these since 3 weeks and I already see a difference in my wellbeing and also energy.

6. Puritan's Pride Super Antioxidant Formula

Puritan's Pride Formula, Softgels by Super Antioxidant


The essential nutrients in our Super Antioxidant Formula are some of the best antioxidants available for fighting free radicals.

Ingredients: Vitamin A Vitamin C Vitamin E Selenium Gelatin, Vegetable Glycerin, Soybean Oil, Corn Oil. Contains <2% of: Natural Caramel Color, Soy Lecithin, Yellow Beeswax.

4.5 out of 5 - more than 200 global ratings

Love these - basically vitamin A. It's the other antioxidant that kicks what ails you. I've noticed dramatic recovery times from illness adding this to a vitamin C regimen. C is only half the equation.

7. Vibrant Health, Spectrum Vibrance, Vegan Antioxidant Superfood Powder

Vibrant Health, Spectrum Vibrance, Vegan Antioxidant Superfood Powder


- Give Your Health a Boost
Experience revitalizing antioxidants from whole foods and botanicals in a convenient, easy-to-mix drink powder

- Fuel Your Vibrance
Capture the power of antioxidants to support your immune system, clear vision, heart health and longevity

- Benefits That Last
Add 1 scoop to water or juice, or blend into a smoothie to add 4.5 servings of fruits and vegetables (plus a boost of antioxidants)

- Get the Whole Spectrum 
Crafted with a broad range of brilliantly colored fruits, vegetables and botanicals like goji berries, apricot, parsley, acai, turmeric and more

- Truth, Trust, Transparency
We carefully source and supply every ingredient, resulting in an unmatched level of product quality and proper potency without proprietary blends

4.7 out of 5 - more than 300 global ratings

Just awesome! I take it every day in my smoothie along with Green Vibrance. It may be overkill, but whatever. You only get one body in this lifetime so if you're going to splurge on anything, let it be in nutrients that will keep you healthy and out of the hospital!! If you are researching this product, do your body a favor and buy it! Your future self will thank you later!


a. Food High in Antioxidants

The following are nutrients with antioxidant activity and the foods in which they are found:
  • Vitamin C: Broccoli, Brussels sprouts, cantaloupe, cauliflower, grapefruit, leafy greens (turnip, mustard, beet, collards), honeydew, kale, kiwi, lemon, orange, papaya, snow peas, strawberries, sweet potato, tomatoes, and bell peppers (all colors)
  • Vitamin E: Almonds, avocado, Swiss chard, leafy greens (beet, mustard, turnip), peanuts, red peppers, spinach (boiled), and sunflower seeds
  • Carotenoids including beta-carotene and lycopene: Apricots, asparagus, beets, broccoli, cantaloupe, carrots, bell peppers, kale, mangos, turnip and collard greens, oranges, peaches, pink grapefruit, pumpkin, winter squash, spinach, sweet potato, tangerines, tomatoes, and watermelon
  • Selenium: Brazil nuts, fish, shellfish, beef, poultry, barley, brown rice
  • Zinc: Beef, poultry, oysters, shrimp, sesame seeds, pumpkin seeds, chickpeas, lentils, cashews, fortified cereals
  • Phenolic compounds: Quercetin (apples, red wine, onions), catechins (tea, cocoa, berries), resveratrol (red and white wine, grapes, peanuts, berries), coumaric acid (spices, berries), anthocyanins (blueberries, strawberries)

b. Do Free Radicals Have Any Benefits?

Your body is continually producing free radicals. Without antioxidants, free radicals would swiftly do serious harm and ultimately cause death. Free radicals do other crucial jobs, though, that are vital for maintaining health. Your immune system, for instance, uses free radicals to combat diseases. Therefore, our body must maintain a certain balance of free radicals and antioxidants.

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