Best Supplement for Knee Cartilage 2022

Cartilage is a strong, flexible connective tissue that protects your joints and bones. Healthy cartilage allows bones to glide over one another, allowing you to move. It also protects bones by keeping them from rubbing together. Maintaining good cartilage health allows you to run, walk, jump, play sports, and do other things you like.

What Cause Cartilage Damage?

Damage to your cartilage can occur suddenly, as in a sports injury or other trauma, or it can build up over time and develop into osteoarthritis.

Osteoarthritis happens when the cartilage that cushions the ends of bones in your joints gradually deteriorates, leading to pain, stiffness, swelling, and immobility. According to the Centers for Disease Control and Prevention, osteoarthritis affects more than 32.5 million adults in the US.

How to Reduce Knee Pain Naturally?

i. Stay at a healthy weight. Extra pounds put pressure on weight-bearing joints like hips and knees. Each pound you gain adds nearly four pounds of stress on your knees and puts six times the pressure on your hips.

ii. Control your blood sugar. High blood sugar can stiffen the tissue that supports your joints and make them more sensitive to stress.

iii. Exercise. Just 30 minutes of exercise five times a week helps joints stay limber and strengthens the muscles that support your knees and hips. Focus on low-impact exercises like walking, cycling or swimming.

iv. Stretch. Gentle stretching can improve your range of motion and keep your joints limber. Try to work in simple stretches into every day.

v. Avoid injury. An injured joint is more likely to develop arthritis than one that was never injured. Wear protective gear when playing sports and always lift with your knees and hips, not your back. 

vi. Quit smoking. Smoking puts stress on tissues that protect your joints and can lead to arthritis pain. Learn how Blue Cross can help you quit.

vii. Eat fish twice a week. Eat fish high in Omega-3s, like salmon, trout and mackerel. Omega-3s have many health benefits and may reduce inflammation.

viii. Get routine preventive care. Your doctor may be able to suggest lifestyle changes that can help reduce your risk or slow the progress of arthritis.

Best Supplement for Knee Cartilage

1. Vimerson Health Glucosamine with Chondroitin Turmeric & MSM

Vimerson Health Glucosamine with Chondroitin Turmeric & MSM


- Supplement for Occasional Joint Discomfort
Whether you’re looking to support your joints through intense exercise, or simply want to relieve occasional joint discomfort, our Glucosamine, Chondroitin, Turmeric & MSM supplement can help keep you active and complement a healthy lifestyle.* This supplement is designed to ease discomfort that may come with age, weight, or athletic deterioration of the joints. It promotes joint health and comfort, supports cartilage and joint flexibility, and helps increase joint mobility.*

- With Turmeric
Turmeric is renowned for its joint-supporting properties, so we’ve added a 4:1 Turmeric extract. By using an extract, we’ve ensured a high curcuminoid content, which promotes joint function and enhances joint mobility.*

- Quality Checked
Made in the USA from global ingredients in a GMP-certified facility. It is non-GMO, shellfish-free, dairy-free, gluten-free, nut-free, soy-free, and pork-free.

4.5 out of 5 - more than 29,400 global ratings

I injured my knee which over time has lost cartilage and swells up from time to time, The orthopedist prescribed an anti-inflammatory, which reduces inflammation, but my knee still feesl stiff and aches. In addition , the Rx bothers my stomach. This prodcut exceeds my expectations. zTaken daily, It not only reduces the inflammation, but it increases the range of motion and my overall cmfort so i have been able to resume my daily 3-4 mile walk without pain. (and no tummy troubles). Gret product!

2. GNC TriFlex | Targeted Joint, Bone & Cartilage Health Supplement

GNC TriFlex | Targeted Joint, Bone & Cartilage Health Supplement


- GNC TriFlex
GNC Triflex Caplets are an every day supplement that provides dietary support for healthy joints and joint cartilage. Formulated with a clinical strength dose of glucosamine and chondroitin, which provides the dietary support for healthy joints and bones, as well as MSM, which delivers sulfur, an important component for healthy joint cartilage.

- Every Day Support
Keeping your joints healthy allows you the chance to keep doing the activities you love. GNC Triflex dietary supplements help support joint tissue and overall health.

- Joint Health
Our well researched, time-tested ingredients support cartilage strength and the ability to maintain healthy joints associated with aging or daily wear and tear. By nourishing naturally-occurring enzymes responsible for joint stability, this formula encourages an increase in mobility and overall wellbeing.

- Formulation
GNC TriFlex combines a clinical strength dose of glucosamine (1500mg) and chondroitin (1200mg) as well as MSM (900mg) — Delivering the building blocks of joint cartilage with proven ingredients. Take 3 tablets daily, preferably with meals.

4.6 out of 5 - more than 1,200 global ratings

This is a great product. Will definitely need this as we age. Help ease joint pain, especially knee pain. It provides cushion to the joints and protects the bone. No side-effects.

3. Orphic Nutrition Glucosamine Chondroitin - Turmeric & MSM 

Orphic Nutrition Glucosamine Chondroitin - Turmeric & MSM

- Flexibility Support* 
The powerful combination of glucosamine and chondroitin sulfate helps support mobility in the knees, hips, & spine*

- Helps Support Strength* 
The cartilage is the cushion between the bones in a joint. These nutritional supplements support the connective tissue in absorbing water to keep it healthy & strong.*

- Supports Joint Health* 
Key elements in this glucosamine chondroitin supplement: curcumin & sulfur. These help support joint health.*

- Supports Overall Health* 
Aside from supporting the recovery of joint cartilage and overall joint health, these joint mobility capsules also support hair, skin, & nail health.*

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

4.4 out of 5 - more than 2,900 global ratings

This glucosamine is easy to swallow and doesn’t leave an after taste in the mouth. It is maximum potency with 1500 mg of glucosamine combined with turmeric (150mg), MSM (25mg), and chondrotin (150mg) as major agents. There are 90 capsules in a bottle, supply for 30 days. If taken on a daily basis gives great joint mobility, helps with cartilage, and stiffness.

As a bodybuilder, I lift weights 5 days a week and joint stiffness usually occurs. I take glucosamine daily and notice a huge difference in my joints.

4. Dr. Bo Glucosamine Chondroitin Turmeric MSM

Dr. Bo Glucosamine Chondroitin Turmeric MSM


- Joint Pain Relief
Glucosamine Chondroitin supplement pills help relieve & support ligament joints & bone cartilage repair. Ease arthritis stiffness & boost anti inflammatory & knees strength.

- Improve Flexibility
Our advanced vitamin joint health supplement helps you flex & move. Reduce inflammation, arthritis & hip, bone, tendon, back & knee pain pills for joint relief & repair.

- Joint Support Health
Our capsules give the best nutrition complex with Turmeric & MSM to help knee pain relief. Boost joint health, extra collagen & cartilage strength.

- Natural 
Our gluten free joint supplement is pure Glucosamine Sulfate, Chondroitin, Turmeric, MSM, Boswellia, Bromelain plus more for max bone joints support vitamins for women & men.

- Made in the USA
Dr. Bo Glucosamine Chondroitin MSM tablets formula is manufactured in the USA to ensure premium quality pills for super knee joint pain relief supplements for men, women & teens.

4.4 out of 5 - more than 600 global ratings

Love this product I've had knee problems and re injured it recently but since I been taking these pills I can feel the difference! My mobility is much better and it allows me to bend my knee alot better!

5. Puritans Pride Glucosamine Chondroitin Complex

Puritans Pride Glucosamine Chondroitin Complex


Glucosamine and Chondroitin Sulfate are key structural components in cartilage and play an important role in the maintenance of joint cartilage. This formulation promotes mobility and flexibility for comfortable joint movement by delivering 500 mg Glucosamine Sulfate and 400 mg Chondroitin; additional ingredients include Vitamin C and Manganese. Adults can take two capsules three times daily with a meal.

4.6 out of 5 - more than 1,500 global ratings

I have noticed with this brand that my joint aches and inflammation have decreased to almost nothing. My workouts have improved and my weak hip feels stronger.

6. Arazo Nutrition Glucosamine Chondroitin Turmeric MSM

Arazo Nutrition Glucosamine Chondroitin Turmeric MSM


- Powerful Joint Relief
A complete dietary supplement for joints; it helps repair cartilage, boost joint mobility, increase joint flexibility, support joint structure and protect joint tissue; suitable for anyone with joint pain, joint inflammation or stiff joints; for men, women and seniors

- Extra Strength Ingredients
Glucosamine 1500mg, Chondroitin 1200mg, Msm 1000mg with Turmeric, Boswellia, Hyaluronic Acid for better joint health, range of motion and comfort; helps rebuild and maintain joint flexibility and ease discomforts that comes with age, weight, or sports related stress

- Safety Checked
Made in a GMP certified facility in America and third party safety tested for purity

4.4 out of 5 - more than 28,000 global ratings

I’ve ordered and reordered these for myself. I have three herniated disks in my spine and these eliminate sciatic nerve pain for me by keeping up cartilage development. I’ve ordered bottles for two of my work associates who have then reordered for themselves.


a. What Causes Osteoarthritis Other Than Old Age?

An injury to the knee and repetitive joint stress from overuse can cause acute, dull, recurring, or chronic pain. If left untreated, it may later lead to osteoarthritis. 

In addition to age and prior injury/ trauma, several other factors including obesity, diabetes, elevated cholesterol, sex, and genetics also increase the risk of developing osteoarthritis. 

b. Stages of Knee Osteoarthritis

Source: Stages of Knee Osteoarthritis


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