14 Best Formula Milk for Newborn Babies in USA 2022

 If you are looking for the best formula milk for baby who is from 0-6 months old in USA, you've come to the right place. Breastmilk is nature's perfect baby food. But if you can’t breastfeed, or if you’ve chosen not to, formula milk is the next best thing. Scientists and medical experts have spent years developing high-quality formula milks that will provide your baby with the nutrition she needs

When you’re deciding which is the best milk powder for your baby, you will need to take several factors into consideration. Think about her health and dietary needs, her age, and the cost and preparation time of different formula milks. 

As a summary, there are three different types of formula:
  • cow’s milk-based formula
  • hydrolysed protein formula
  • soya-based formula
It’s most likely your baby can have cow’s milk-based formula, unless there’s a health or dietary reason why she can’t. 

Update: Many of the infant formula products are out of stock on Amazon. You may wish to keep your options open to multiple online and offline channels or visit the site regularly to check whether the items are back in stock.

Best Infant Formula USA 2021

There are many different brands for baby or infant milk formulas in USA. We have trawled through the reviews, Google search results and milk powder comparison information available on blogs and forums, and shortlisted the best for you. Here are the best baby milk powders you can buy online in USA today.


1. Gerber Good Start Hypoallergenic Formula




Of all infant food allergies, cow’s milk protein allergy, or CMPA, is the most common. It occurs when a baby’s immune system reacts to the proteins in cow’s milk. You can feel confident that Gerber Good Start Extensive HA with Iron is clinically shown to be hypoallergenic, and is made with all the essential nutrients needed to promote adequate growth.

- Infant Formula with Iron 
- Designed for babies with cow’s milk protein allergy (CPMA)

Hypoallergenic Nutrition
This hypoallergenic formula is designed for babies with cow’s milk protein allergies (CMPA). If your baby is suspected to have or is diagnosed with CMPA, your baby’s doctor might recommend changing from a routine formula to a hypoallergenic extensively hydrolyzed infant formula

For Cow's Milk Protein Allergy
Cow’s milk protein allergy is the most common allergy among infants. This formula features 100 percent high-quality whey protein, broken down into tiny pieces and is designed to be well-tolerated

Gerber Good Start Extensive HA Reviews : 4.3 / 5 - 476 Ratings on Amazon

Before you give up, try this. My son spent the first 12 weeks of his life sick from formulas. He was allergic to lactose we tried regular similac, soy, gentle ease, etc. until we tried the HAs. He first went on Nutramigen which gave him the diaper rash from hell. His skin was peeling off. We switched to alumentum and he didn’t poop for days. So the doctor recommended Elecare which he refused to drink and choked on to the point that I almost had a nervous breakdown. His pediatrician randomly gave us this to try in samples from her office. It was the best accident that could’ve ever happened. 1. He drank it easily 2. No diaper rash 3. Regular poops. It takes a few days for the gas to go away but he’s been on this for 2 months now and he’s a new baby. We add probiotic drops (mommy’s bliss brand) to one bottle a day and I swear the combo is a godsend.


2. Similac Pro-Advance Non-GMO Infant Formula with Iron



Similac has one of the widest range of milk powders in USA.

Similac Pro-Advance is their closest formula to breast milk. This baby milk formula is a well-formulated baby formula with 2’-FL human milk oligosaccharide that provides immune support to the baby by encouraging immune cells to release protective proteins in amounts more like the breastfed baby.

This baby Milk formula for 0-6 Months baby is also one of the leading infant formula with no artificial growth hormones.

More about the baby milk formula
  • 2'FL HMO (Human Milk Oligosaccharide) adds another layer to Similac’s already proven immune support
  • DHA, Lutein, and Vitamin E for Brain & Eye Development
  • Highly recommended by mothers
  • No Artificial Growth Hormones
  • Backed by more than 15 years of extensive research
Ratings : 4.8 out of 5 - 1,274 global ratings

I bought this for my great grandbaby who was born with a heart defect. It really helped her to gain weight that she needed but now the Dr. is changing her formula.



3. Enspire Gentlease




Enfamil Enspire is touted as the most similar milk formula to breast milk because it has Lactoferrin, unlike Neuro Pro. It contains hydrolysed milk proteins, making it easier to digest. Lactoferrin helps support the microbiome and prevents gastrointestinal infections. It is certified to be non-GMO. 

It uses cow’s milk. It is also enriched with various plant-based ingredients to provide complete nutrition for your baby. However, since it contains cow’s milk and soy, it is not suitable for babies who are allergic to such ingredients.

Main ingredients : nonfat milk, whey protein-lipid concentrate, whey protein concentrate, lactose, and vegetable oil (which consists of coconut oil, soy oil, high oleic sunflower oil, and palm oil). 

Sub Ingredients
Added vitamins and minerals, lactoferrin, polydextrose, galactooligosaccharides, crypthecodiniumcohnii oil, and mortierellaalpina oil.

Polydextrose is a soluble fiber that usually acts as a sweetener for sugar-free and diabetic recipes. Unlike sugar, polydextrose doesn’t significantly increase the caloric count of the infant formula.


Adopted a newborn baby boy and this is the formula I decided to use because of the added "colostrum" type properties! As a farmer, we always use a colostrum type of formula at first for baby animals that don't get to nurse from mom. Didn't try this for our newborn until he was brought home at 4 days old, but he did excellent on it! He was Jaundice and I felt he still could benefit from a formula with the colostrum type properties. No spitting up at all! And the gas he had from the hospital's Similac formula, totally stopped after a full day on the Enspire! He used up the entire container after 10 days... (big baby, big eater). He was also cleared of his Jaundice at his 1st checkup! I switched him to the Enfamil Neuro-Pro Gentlease now that I don't feel the need for the extra "colostrum" benefit. He made the switch with ease and is now doing great on that too! But definitely a great 1st formula! I'm a foster mom and will definitely keep this on hand and use this with any newborn placements I get... as long as they don't have any specific dietary needs!!


4. HiPP Combiotic Infant Formula Stage 1



HiPP is one of the world’s leading baby food and formula manufacturers. Everything they create is made from only organic or naturally farmed ingredients. Adhering to strict guidelines, HiPP formula is as pure and nutritious as anything available on the market anywhere in the world.  

Designed for babies ages 0 to 6 months, HiPP Combiotic Infant Formula Stage 1 is the perfect nutritional balance for small growing bodies. With vitamins and minerals, prebiotics and probiotics, and Omega-3 and 6 fatty acids, this whey-based formula is ideal for babies.

HiPP Combiotic Stage 1 Formula is a perfect addition to breast milk or used as the only source of nutrition. In later months, as the baby begins to eat cereals and solid foods, this formula can be used to mix with organic grains.

HiPP Combiotic formulas are designed to include probiotic and prebiotic ingredients. Probiotics are gut flora that aid in digestion and provide immune support. Prebiotics are dietary fibers that feed healthy intestinal flora. This combination gives babies a solid, healthful gut that helps their immune system and digestion.

- Vitamins A, C, and D and iron
- Soy-Free
- No starch added
- Fortified with vitamins to create a healthy immune system
- Contains Prebiotics and Probiotics
- No added sugar
- Gluten-free
- Constantly checked to make sure it meets the highest legal, safety and nutritional requirements
- Instant preparation, ready in minutes. Just add boiled water and shake well

This is truly the next best thing to mother's milk. Previously was supplementing with another formula that stained my son's clothing yellow, his burps smelled bad and the milk itself was a brown color. Once we switched to HIPP, it's hard to tell the difference between the formula and breastmilk and the burps do not smell. Most importantly baby's poop also resembles that of breastfed baby poop! If recommend this brand to anyone as it's the best thing you can offer your baby.

5. Earth's Best Organic Dairy Infant Powder Formula





Earth's Best Organic Infant Formula with Iron is our closest formula to breast milk. The formula is fortified with iron for red blood cell development and contains DHA and ARA, two fatty acids found in breast milk that help support brain and eye health. With lutein for eyes and prebiotic fiber for immunity, this is a fantastic formula solution for your little one.

- With Iron, Omega-3 DHA and Omega-6 ARA
- Organic formula that is easy to digest
- Nutritionally complete for baby's first twelve months
- All lactose milk based powder formulation, no added corn syrup solids. 
- Water assisted extracted DHA
- Omega 3 DHA and Omega 6 ARA fatty acids naturally found in breast milk to support brain and eye development, Iron for healthy development
- With Lutein for Eyes and Prebiotic Fructooligosaccharides for Immunity
- Non GMO ingredients and Kosher
- Made without prohibited synthetic pesticides and fertilizers
- No artificial growth hormones 

This has been a god-send. I feel comfortable giving it to my daughter, it doesn’t upset her stomach, and she loves it! Absolutely loves it- she smiles and giggles when she sees me shake up a bottle (unfortunately this didn’t help my breastfeeding quest and she much prefers the bottle). But I am so thankful to Earths Best for making an affordable and healthy organic option made with lactose. 

4.7 out of 5 - 3,925 global ratings




6. Gerber Good Start Soothe (HMO) 



- Non-GMO Powder Infant Formula
- For infants up to 12 months old experiencing colic, excessive crying, fussiness and gas
- With Iron, 2’-FL HMO and Probiotics for Digestive Health and Immune System Support
- Soothing Nutrition: Modeled after the complete nutrition and gentleness of breastmilk
- Features prebiotics, comfort proteins and probiotics that improve the good bacteria in tummies and promote soft stools


Our 2nd baby was born with a sensitive stomach unfortunately. We tried enfamil for sensitive tummies and similac. He was still waking up nearly every hour with gas pains. Our pediatrician recommended Gerber and he slept 3 solid hours for the first time that night: we were beyond thrilled!
3 months later and he is almost sleeping through the night. This formula seems to really agree with his gut.

4.8 out of 5 - 1,819 global ratings




7. Happy Baby Organic Stage 1 Infant Formula



- For babies from 0 to 12 months with sensitive bellies
- Provides a complete nutrient blend with lactose reduced by 75% to ease occasional fussiness & gas in lactose-sensitive babies
- Digestive Support: Our prebiotic mix (GOS & FOS) mimics the function of prebiotics found in breast milk 
- Non-GMO & Gluten-Free


My baby was born in March and we tried a lot of formulas. They made him constipated, projectile vomit, or gave him colic all night long. I tried 10-12 different formulas. My pediatrician then recommended I go for soy, since he figured baby had a milk allergy. I didn't want to go that route, so I tried this as a last resort. My baby started to sleep during the night again and he wasn't constipated or vomiting at all. He doesn't even have spit-up with this one. It has been wonderful and he's almost 6 months now. He's growing at a healthy rate and enjoys his milk.

To add, I tried some formulas that smelled so bad I felt I gagged. This one doesn't smell bad at all. The only con is the price and that I can only find it on Amazon or Target.

4.7 out of 5 - 2,894 global ratings



8. Kendamil Goat Milk Formula Stage 1 - Best Goat Milk Formula for Acid Reflux



Why choose Kendamil Goat milk formula instead of the Kendamil cow milk formula? Goat milk is easier to digest than cow milk and the A2 milk makes the formula easier for infants to absorb. The added HMOs make this Goat milk formula different than the other options on the market as well.

- For newborns 0-6 months old
- You can supplement breastmilk with Kendamil Goat or use it alongside. 
- Produced in the United Kingdom
- The selenium and natural prebiotics found in Kendamil Goat milk formula are similar to breastmilk, boosting your baby's immune system.
- Made with 100% full cream goat's milk that is loaded with prebiotics. 
- Kendamil is rich in vitamins—such as iron, Vitamin A, Vitamin C, and Vitamin D
- Organic Prebiotics from whole A2 Goat Milk
- No Palm Oil (Coconut Oil instead)
- No added sugars or synthetic preservatives
- No Fish Oil, plant based DHA instead
- No wheat, soy, maltodextrin or peanut ingredients
- Omega-3 and 6 LCPs (DHA & ARA) for brain development (without hexane extraction)
- Main Carbohydrate is lactose
- GMO-free



9. Bobbie Organic Infant Formula



Bobbie is a nutritionally complete, milk-based infant formula intended for full term, healthy infants (0-12 months of age). Bobbie’s protein ratio is similar to the protein ratio of breast milk and is designed to support gentle digestion, supporting those growing little tummies while being easy on the gut.

- It contains water-extracted (not hexane-extracted) DHA to help support brain development.
- Bobbie is one of the only U.S. formulas meeting both European & U.S. requirements for iron.
- All infant formulas are required to go through strict manufacturing procedures. 
- Bobbie contains highly refined coconut oil, which does not contain allergens. 
- Bobbie is not suitable for premature infants or infants with allergies to milk or soy.
- Gluten-free
- No palm oil, no corn syrup
- Non-GMO (ingredients not genetically engineered)
- No Maltodextrin
- No added natural or artificial flavors and colors (like all infant formulas)



Soy Formula

10. Enfamil ProSobee Lactose Free Formula



- Designed for babies who cannot digest cow’s milk proteins. 
- Suggested to try Enfamil’s Nutramigen first before switching to soy.
- Uses corn syrup as the first ingredient and vegetable oils as the second.
- Uses soy protein isolate as the third ingredient, completely avoiding milk-based products.
- Con : Parents have given feedback that it may cause constipation


We have to use soy based formula because my baby has cow milk intolerance. It caused really bad constipations on my baby, and I switched the brand immediately after taking it only for three days. It still took two weeks to cure it. My baby has no more constipation after using the other brand. And you can see the corn syrup of this formula is really high, much higher than the other brand.


11. Similac Soy Isomil : Similac Lactose Free Formula



- For babies who cannot digest cow’s milk proteins. 
- Suggested to try Similac’s Alimentum before switching to soy.
- Uses corn syrup as the first ingredient and soy protein as the second ingredient followed by oils. 
- Completely avoids milk products.
- High Linoleic Acid levels

Similac Soy Isomil Reviews : 4.7 out of 5 - 227 global ratings on Amazon

My newborn seems to be adjusting to this milk nicely. He was terribly gaseous with Neosure, Similac Pro, Alimentum too and I tried Soy Similac and it’s been very helpful. I also add 1 oz of pear or prune juice to the bottle to assist him in passing his stool per the Dr. direction and he is no longer crying and passing extreme gas as before.

Similac Soy Isomil Price, 30.8oz - $147.96 on Amazon


11.5 - Enfamil ProSobee vs Similac Soy Isomil


- Both are for babies who cannot digest cow’s milk proteins. 
- Suggested to try Enfamil’s Nutramigen or Similac’s Alimentum before switching to soy.
- Both formulas use corn syrup as the first ingredient.
- Both use soy protein isolate, completely avoiding milk-based products.

Differences
- Enfamil has soy protein as the third ingredient, after corn syrup and vegetable oils
- Similac uses soy protein as the second ingredient followed by oils
- Similac adds more sugar to their soy formula than Enfamil
- Similac has a higher Linoleic Acid levels




Amino acid-based formulas offer complete nutrition for babies who need additional nutrition support. These formulas are appropriate for children who are unable to tolerate extensively hydrolyzed formulas. Because these formulas do not contain any intact proteins, they are tolerated by most children. Amino acid-based formulas are also known as “elemental” formulas.


12. Elecare Hypoallergenic Formula



- Complete Nutrition For Severe Food Allergies
- Amino Acid-based Infant Formula

IMPROVED SYMPTOMS: Well-tolerated formula clinically proven to help improve symptoms of severe food allergies and other GI conditions.

SUPPORTS GROWTH: Complete nutrition specially formulated to help growth & development in infants who need it most.

AMINO ACID-BASED FORMULA: Made with 100% free amino acids as the protein source for infants who cannot tolerate intact or hydrolyzed protein.

BRAND: Recommended by pediatric gastroenterologists; clinically shown to support growth and development.

THE CHOICE IS CLEAR: A trusted amino acid-based, hypoallergenic formula that has DHA and ARA


We loved this. My son had allergic colitis. Dairy and soy caused ulcers in his colon and the ulcers would bleed. We would find blood in his stools and jelly like clots. He was born 6lbs 2oz but two weeks after birth he was down to 5lbs 6oz. We couldn't figure out why he was having such a hard time. The pediatricians kept giving us soy and Alimentum but to no avail. He continued to bleed. Eventually our GI doctor suggested Elecare and gave us a few cans to try. She warned us that it was very expensive and never heard of anyone getting it covered by medical insurance. I purchased a can from Amazon once or twice. Eventually I found it too costly and called my health insurance and begged for coverage. I explained that we had no other options on feeding him. (Even my breast milk caused the bleeding.) The coverage nurse agreed it was necessity and Electra was billed as a medical supply. If your baby really needs this to thrive, please consider contacting your health insurance. All we had to do was order the shipment and 9 cans would come per month.



13. Alfamino Infant Amino Acid Based Formula with Iron


Alfamino is a hypoallergenic amino acid based infant formula designed for infants with cow's milk protein allergy, multiple food allergies or malabsorptive conditions.

Nutritionally Complete Formula : Alfamino provides essential nutrients that infants need for growth and development and has a unique fat blend containing medium chain triglycerides (MCT) to facilitate fat absorption.

Hypoallergenic Pediatric Formula : Appropriate for conditions of severe malabsorption, Alfamino formulas offer unique compositions with tailored nutrient profiles and highly selective ingredients.

Use Under Medical Supervision : Alfamino Infant Formula is easy to digest and is lactose free and gluten free

- For infants 0 to 12 months

Alfamino Formula Reviews : 4.4 / 5 - More than 150 Ratings on Amazon

So thankful for this formula. My infant has FPIES and malabsorption and this is the only elemental formula with 10% more MCT oil than the others and actually helps him gain weight. He can tolerate it much better digestively and it doesn’t smell anywhere as bad as other elemental formulas so I can only imagine it tastes better as well.




14. PurAmino Hypoallergenic Infant Drink




- With Omega-3, DHA, Iron

SUITABLE FOR TUBE FEEDING: Puramino Jr is appropriate for both oral and tube feeding.

FROM ENFAMIL: PurAmino is an iron-fortified, hypoallergenic, amino acid-based infant formula for the dietary management of infants with severe cow’s milk protein allergy (CMA), not effectively managed by an extensively hydrolyzed formula

SUITABLE FOR MANY DIETARY CONDITIONS: PurAmino is also suitable for other conditions that may require an elemental diet including - Eosinophilic esophagitis, Short bowel syndrome, Malabsorption, Protein maldigestion

NUTRITIONALLY COMPLETE FORMULA: For infants and toddlers 0-24 months with DHA and ARA, nutrients also found in breast milk that promotes brain and eye development

EXPERT RECOMMENDED DHA: PurAmino has expert recommended DHA which provides brain-building nutrition

HYPOALLERGENIC: 100% Amino-Acid based, iron-fortified formula, suitable for infants & toddlers with lactose intolerance


Only thing my son can drink. What I didn’t know after months n months of purchasing these on here. Is that you can have ur pediatrician sign a paper and send it to your insurance company. And they pay for everything and have it sent directly to your home. 




FAQ

1. Milk Allergy vs Lactose Intolerance

For milk allergies, the baby’s immune system reacts negatively to the proteins in cow’s milk. Breastfed babies are reacting to the dairy his mother has eaten (the milk proteins pass through breast milk), while formula-fed babies are reacting to the cow’s milk proteins in the formula. In either case, a baby's immune system sees the cow’s milk proteins as foreign substances.

Milk intolerance, on the other hand, has nothing to do with cow’s milk proteins or the immune system, and instead has to do with the digestive system. Your child might have loose stools or blood in stool hours or days later.


2. How Do I Know If My Baby Has A Milk Allergy?

If your baby shows the following symptoms, do see your pediatrician to check if your baby has a milk allergy.

- Frequent spitting up
- Vomiting
- Signs of abdominal pain, or colic-like symptoms, such as excessive crying and irritability (especially after feedings)
- Diarrhea
- Blood in stool
- Hives
- A scaly skin rash
- Coughing or wheezing
- Watery eyes and stuffy nose
- Trouble breathing or a bluish skin color
- Swelling (especially of the mouth and throat)


3. How do I stop my baby from vomiting after feeding?

- Avoid overfeeding. If the baby's stomach is too full, some of the contents might be pushed back out. To reduce overfeeding, feed your baby smaller amounts more frequently.

- Burp your baby frequently. Extra gas in the stomach causes gas bubbles to escape, which has a tendency to bring the rest of the stomach's contents up as well. Burp after and during meals.

- Limit active play after meals

- Hold your baby upright. Pressing on a baby's belly right after feeding may push their stomach contents out. 

- Consider the formula. Frequent vomiting may serve as one of several signs that it's time to consider alternative formulas with your pediatrician. 

- Give oatmeal. Only recommended for babies after 6 months old. Babies with reflux may need thicker food to order to swallow safely or reduce reflux. 


4. What to do after baby throws up?

- Rest their stomach. Keep your baby from eating or drinking for 30 to 60 minutes after vomiting so that their stomach has time to recover.

- Give them fluids. after 3o minutes, start by giving your baby small amounts (0.5 oz or less) of fluid every 5 to 10 minutes. If your baby vomits the fluid out, wait another 30 minutes. Then start again with small amounts of fluid every 5 to 10 minutes. Use water, breast milk or a clear, noncarbonated liquid. 

- Medicines. If your child has a fever, ask your pediatrician for the appropriate medication.


5. When Will My Baby's Reflux Go Away?

A normal baby with mild acid reflux may spit up after feedings, but usually isn’t irritable. This problem usually stops after 12 months.


6. How To Soothe Baby Acid Reflux

- Rest their stomach. Keep your baby from eating or drinking for 30 to 60 minutes after vomiting so that their stomach has time to recover.

- Give them fluids. after 3o minutes, start by giving your baby small amounts (0.5 oz or less) of fluid every 5 to 10 minutes. If your baby vomits the fluid out, wait another 30 minutes. Then start again with small amounts of fluid every 5 to 10 minutes. Use water, breast milk or a clear, noncarbonated liquid. 

- Medicines. If your child has a fever, ask your pediatrician for the appropriate medication.


7. How can I treat my baby's reflux naturally?

- Avoid overfeeding. If the baby's stomach is too full, some of the contents might be pushed back out. To reduce overfeeding, feed your baby smaller amounts more frequently.

- Burp your baby frequently. Extra gas in the stomach causes gas bubbles to escape, which has a tendency to bring the rest of the stomach's contents up as well. Burp after and during meals.

- Limit active play after meals

- Hold your baby upright. Pressing on a baby's belly right after feeding may push their stomach contents out. 

- Consider the formula. Frequent vomiting may serve as one of several signs that it's time to consider alternative formulas with your pediatrician. 

- Give oatmeal. Only recommended for babies after 6 months old. Babies with reflux may need thicker food to order to swallow safely or reduce reflux. 

- Avoid tight diapers or clothing



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