Best Black Seed Oil with Highest Thymoquinone 2024

Thymoquinone (TQ) is the primary active ingredient in black seed oil (BSO, Nigella sativa oil or black cumin oil). TQ has been shown to have a variety of pharmacological effects, including anti-inflammatory, hypoglycemic, antioxidant, immune stimulator, and anticancer properties.

Moreover, Thymoquinone may have potential benefits for preventing and curing COVID-19. Studies have shown that TQ may have an inhibitory effect on SARS CoV2 proteases, which could diminish viral replication, and it has also demonstrated good antagonism to angiotensin-converting enzyme 2 receptors, allowing it to interfere with virus uptake into the host cell (Source).

Black Seed Oil with Highest Thymoquinone


1. Contains 20% Thymoquinone | Triquetra TQ-Advanced 4X Black Seed Oil Extract Capsules
2. Contains 10% Thymoquinone | Nootropics Depot Nigella Sativa Extract Capsules – Black Seed Oil Extract
3. Contains 5% Thymoquinone | Triquetra Black Seed Oil TQ Advanced
4. Contains 5% Thymoquinone | Nootropics Depot Nigella Sativa Extract Capsules
5. Contains up to 4.34% Thymoquinone | Bionatal Black Seed Oil
6. Contains 3.92% Thymoquinone | Nourishing Nutrients Organic Black Cumin Seed Oil

1. Triquetra TQ-Advanced 4X Black Seed Capsules - 20% Thymoquinone Black Seed Oil

The best black seed oil capsules with highest thymoquinone.

Thymoquinone (TQ) is the nutrient in Black Seed Oil that gives it such a wide range of benefits. TQ-Advanced 4X is a powdered extract that delivers Thymoquinone in its most concentrated form at 20%. TQ-Advanced 4X is Vegan, GMO-free, Filler-free, Soy-free, Dairy-free, and Preservative-free. It is 3rd-party tested for over 100+ contaminates and microbials, and it is manufactured in the USA in the highest quality GMP regulated facility.

– Derived from Nigella Sativa, Naturally Occurring Thymoquinone, Delivered in Raw Form
– With 500 mg in each capsule that is 100 mg of Thymoquione

Ratings: 4.3 out of 5 – more than 1,000 global ratings on Amazon.

Triquetra Black Seed Oil with Highest Thymoquinone Review
These helped day one of my chronic asthma/allergy/nasal/throat/chest congestion I have had for months. After a week I have not needed to take my allergy meds. It has cleared my nasal passages. I did not expect it to work so well because I’ve tried many homeopathic meds that have given me strange side effects.
I love this product and will continue to use it. It’s worth the extra cost. If you need it for other ailments I cannot vouch for that. I bought it solely for my nasal/asthma issues and it’s worked wonders for me.

2. Nootropics Depot Nigella Sativa Extract Capsules - Black Seed Oil Extract 10% Thymoquinone

All Nootropics Depot products are thoroughly lab tested to ensure our customers are receiving only the highest quality ingredients at the optimal strength, potency and purity. We take pride in the amount of research put into every product by sourcing only the highest quality and innovative ingredients.

– Nigella Sativa Extract Capsules | 200mg
– Also Known as Black Seed Oil Extract
– Minimum 10% Thymoquinone Content

4.5 out of 5 – more than 240 global ratings

Nootropics Black Seed Oil Extract with Highest Thymoquinone Review
This product was expected to arrive Sunday but instead arrived the previous Wednesday, which was great because I was excited about trying it. I’ve used similar products before, but they had only about 1% 
Thymoquinone content, which in itself was great. I figured if 1% worked so well for me, then 5% would be even better! I know people who are using this product to regulate blood pressure, glucose, asthma, allergies, and digestive problems.
 I use it for overall good health, and it’s really been a blessing to have a product such as this help me in my quest to stay healthy. I feel great…small digestive issues have changed for the better, and high pollen counts no longer bother me the way they did in the past. I will definitely recommend this product to others and will be stocking it on my shelves at home as well.

3. Triquetra Black Seed Oil TQ Advanced - 5% Thymoquinone

Triquetra Black Seed Oil TQ Advanced

TQ Advanced is vegan, GMO-free, filler-free, soy-free, dairy-free, and preservative-free. It is 3rd party tested for over 100+ contaminates, and it is manufactured in the USA in the highest quality GMP regulated facility.

Can Also Be Used Topically on Skin & Hair: Black Seed Oil is often used as a health and beauty secret for skin and hair. TQ Advanced is also highly effective for topical use to improve skin health and appearance, fight skin infections, improve hair health, prevent hair loss, and improve scalp health.

– 5% Thymoquinone
– Each 2-gram serving of TQ-Advanced is derived from 30 grams Nigella sativa species of Black Seed. The oil is delivered in raw form, maintaining its full bioactive components.

4.5 out of 5 – more than 770 global ratings

Triquetra Black Seed Oil for Skin Review
I have been using this black seed oil on my face for about a month (I wear it at night) and have seen a MASSIVE improvement. I do not say this lightly! This oil truly has made a positive impact on my skin’s clarity, suppleness and texture. My co-workers have pointed out my skins improvement as well, which tells me there truly is a difference…I definitely recommend!

4. Nootropics Depot Nigella Sativa Extract Capsules - 5% Thymoquinone

Black Seed Oil supports Cognitive Function, Memory, Liver Health, and Immune Function. Promotes Weight Loss, Mood, and Healthy Stress Levels

– Nigella Sativa Extract Capsules | 200mg
– Also Known as Black Seed Oil Extract
– Minimum 5% Thymoquinone Content

4.5 out of 5 – 240 global ratings

Nootropics Depot Nigella Sativa for boost energy Review
Ever feel like once 2pm hits you’re done working for the day and have little energy left? Pop one of these little pills and you will be energized for the next 4-5 hours! I was skeptical about the pill being small but it works!

5. Bionatal Black Seed Oil - Up to 4.34% Thymoquinone

Bionatal black seed oil

Black Seed Oil with Up To 4.34% Thymoquinone

BioNatal’s main product is produced from Nigella Sativa seeds. We use only the best pure black seeds from Ethiopia, as—after comparing many seed analyses over the course of four years—we found that only Ethiopia has the highest quality seeds.

This manual method also allows BioNatal always to provide fresh oil. We extract in small portions and only to meet what our customers demand. When buying BioNatal black seed oil, be at peace and know that your bottle was packaged right after the 30-35 days sediment process. Our labels will always provide you with the latest production date!

6. Nourishing Nutrients Organic Black Cumin Seed Oil

Nourishing Nutrients Organic Black Cumin Seed Oil

Some oils claim to be high TQ, but do not prove it with 3rd party testing. With batches varying due to nature, our oil ranges from over 1% to over 2% TQ. Current batch is a huge 3.92% TQ.

If you take cold pressed Black Seed Oil regularly, you can support your immune system to fight off illness. Packed full of antioxidants, amino acids & thymoquinone. Also, a superior source of vegan EFA’s (3,6, and 9). Known as Kalonji & Nigella Sativa oil.

4.5 out of 5 – more than 380 global ratings

Nourishing Nutrients Organic Black Seed Oil Review

This is the best Black Seed Oil I have tried hands down. It equalizes my blood sugar, improves sleep and the reason I began using it was for weight loss. My family and friends are shocked that I am promoting anything as a weight loss miracle product. When my mom saw me after 2 weeks she did not recognize me at first. Cumin broke a 6 month plateau. I will be a life time customer.

7. Turkish Black Seed Oil: Immune & Digestive Booster

Introducing Mother Nature Organics' premium Organic Turkish Black Seed Oil, extracted from Nigella Sativa seeds using a cold-pressing method to ensure maximum potency and wellness benefits. Each teaspoon of this Virgin & Unrefined Black Cumin Seed Oil is packed with a high TQ content, making it a powerful herbal superfood for promoting overall wellness.

This remarkable black seed oil contains a potent combination of Omega 3, 6, and 9, as well as thymoquinone, which promotes healthy cell activity in the body, boosts immune defense, and improves restful sleep. Its natural composition of amino acids, antioxidants, and omegas makes it an ideal choice for those looking to improve hair strength and fullness, rejuvenate skin for a youthful appearance, and support joint mobility.

Unlike the strong Indian variant, this Organic Black Seed Oil from Turkey has a smooth, mild taste that is perfect for those who prefer a milder flavor. Rest assured that this oil contains a minimum of 1.5% TQ content, ensuring its effectiveness in promoting wellness. It is also Non-GMO, solvent-free, alcohol-free, gluten-free, and cruelty-free, making it a safe and healthy choice for everyone.

Mother Nature Organics manufactures and packages this Cold Pressed Black Seed Oil Liquid in a GMP-certified facility in the United States. They test every batch to ensure that each bottle is packed with high-quality black cumin seed oil and meets all quality standards. This oil is organic and free of heavy metals and impurities, making it a superior choice compared to other supplements.

Ratings: 4.5 out of 5 – more than 4,000 global ratings

Best Black Seed Oil With Highest Thymoquinone FAQs

Do all black seed oil products have thymoquinone?

Yes. But not all Black Seed Oils or the dosage of thymoquinone is the same.

Can you take too much black seed oil?

Short-term use of three months or less has not been linked to any serious side effects. While short-term use of black seed oil may be beneficial, long-term use may have other unwanted effects. One study of the chemical composition of black seed oil shows that the majority of fatty acids are from linoleic acid, an omega-6 polyunsaturated fat or (PUFA).

Black seed oil side effects on the kidneys
However, there’s also concern that taking too much black seed oil could harm your kidneys. In one reported case, a woman with type 2 diabetes was hospitalized for acute kidney failure after taking 2–2.5 grams of black seed capsules daily for 6 days (Source).

What is the best time to take black seed oil?

It is recommended that you consume it raw in order to get the full benefits. This oil should not be heated. Furthermore, studies and experts recommend that this oil be taken on an empty stomach before meals and before going to bed.

Who should not take black seed oil?

– Pregnancy: Black seed is commonly consumed in foods. However, taking amounts higher than those found in foods while pregnant is probably risky.

– Breast-feeding: There is insufficient reliable information to determine whether black seed is safe to use while breast-feeding. To be on the safe side, avoid using it.

– Children: Black seed oil is possibly safe for children when taken orally in short term and in recommended weight amounts.

– Bleeding disorders: Black seed has been linked to slowed blood clotting and an increased risk of bleeding. Black seed may aggravate bleeding disorders.

– Surgery: In some people, black seed may slow blood clotting, lower blood sugar, and increase sleepiness. This can cause drug interactions during and after surgical procedures.

Are All Black Seed Oil Products the Same?

The terms black seed oil, black cumin seed oil, and nigella sativa oil are all referring to the same oil. 

However, not all Black Seed Oils Supplements contain the same amount of thymoquinone. Many brands claim to have high thymoquinone levels and are priced at competitive value. Therefore, we should be careful with misleading claims.

How Much Black Seed Oil Should You Take a Day?

The dosage that should be used depends on the type of inflammation, condition, or issue that is being treated. Adults have most commonly used black seed oil in doses of 1-2.5 grams by mouth daily for 4-12 weeks.

It is best to consult with a doctor to ensure that using black seed oil is safe for them and to determine the appropriate dosage.

According to a 2021 study on the safe levels of thymoquinone, adults should limit their daily usage to 900 milligrams (mg) of the oil or 48.6 mg of thymoquinone to reduce the risk of side effects. (Source)

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