8 Best CoQ10 Supplements 2022

One of the most well-known supplements for heart health and general wellness is Coenzyme Q10 or CoQ10. Studies also linked it to blood sugar regulation, fertility, cancer prevention, and even migraine control. 

As you become older, your body produces less CoQ10. Additionally, it has been discovered that CoQ10 levels are lower in those who have specific diseases, such as heart disease, and in those who take statins (cholesterol-lowering drugs).

Coenzyme Q10 Benefits

a. CoQ10 for Cardiovascular Health
Clinical evidence shows that CoQ10 supplementation with doses of 200 mg/day or higher for prolonged periods is safe, well-tolerated, significantly increases the concentration of CoQ10 in plasma, and reduces oxidative stress and mortality from cardiovascular causes.

b. CoQ10 for Type 2 Diabetes Mellitus (T2DM)
Patients with T2DM frequently have CoQ10 deficiency. Restoring CoQ10 levels in T2DM patients may reduce oxidative stress, protect mitochondrial function, and ultimately result in better glycemic control.

c. CoQ10 for Fertility
CoQ10 is a powerful antioxidant and can lead to a higher rate of fertilization and more high-quality embryos. Moreover, CoQ10 can improve ovulation and increase the number of ovarian follicles. For men, CoQ10 with vitamin C and E can effectively improve semen parameters in infertile men.

d. CoQ10 for Cancer Prevention
Coenzyme may lower your risk of developing some cancers and strengthen your immune system. In addition, it can shield your heart from the negative effects of some chemotherapy.

e. CoQ10 for Migraine Control
According to a study  CoQ10 appears to have beneficial effects in reducing duration and frequency of migraine attack.

CoQ10 Recommended Dosage

CoQ10 dosages of 90 to 200 mg per day are often advised, while larger doses of 300 to 600 mg may be necessary for specific illnesses. CoQ10 is a supplement is generally well-tolerated and safe.

Best CoQ10 Supplements

1. Nature Made CoQ10 Supplement 100 mg

Nature Made CoQ10 100 mg, Dietary Supplements for Heart Health and Cellular Energy Production

- What's Inside?
Contains one 72 count bottle of Nature Made CoQ10 100 mg Softgels for a 72-day supply. Adults take one of these CoQ10 supplements daily with water and a meal

- Best CoQ10 100 for Heart Health and Cellular Energy Production
Nature Made CoQ10 100 mg heart health and cellular energy supplement helps support heart function and cellular energy production.

- Safe Ingredients
This Coenzyme Q10 supplement is gluten free with no artificial flavors, no color added, and no preservatives.

4.7 out of 5 - more than 3,400 global ratings

I bought it for my brother in law. He is about 60 now, and has little heart problem. In order to reduce heart condition risks, I bought it and asked him to try out for many months. He told me that he noticed a difference and feel better. Also the price is reasonable and cheaper than any stores like RiteAid. I strongly recommend it as part of a long-term heart health plan.

2. Nature's Bounty CoQ10 Supplement 200mg

CoQ10 by Nature's Bounty, Dietary Supplement, Supports Heart Health, 200mg, 80 Softgels


- For Your Heart 
80-count, 200mg CoQ-10 Rapid Release Softgels. Coenzyme Q-10 is one of the leading supplements recommended to help promote cardiovascular health.(1) Nature’s Bounty CoQ-10 can even replenish what statin medications may deplete.

- For Your Energy
Nature’s Bounty CoQ-10 Softgels help convert food into energy. CoQ-10 is found in every cell in the body and is an important part of the body’s cellular energy production machinery.

- Important Antioxidant
Only Nature’s Bounty CoQ-10 contains a clinically studied ingredient called Q-Sorb. This important antioxidant can help fight free radicals within the body.

- Purity is Our Priority 
Nature’s Bounty is committed to safety and purity in all our supplements. Our CoQ-10 rapid release softgels are non-GMO, gluten-, lactose- and sugar-free, and contain no artificial, sweeteners or flavors.

- Trusted Wellness Experts
Nature’s Bounty CoQ-10 Softgels are a product of nearly 50 years of dedication to quality, consistency and scientific research to make vitamins and nutritional supplements of unrivaled excellence.

4.7 out of 5 - more than 2,550 global ratings

Recommended by cardiologist and neurologist for circulation improvement and heart health in addition to prescription medicine regime. Used for three years and happy with continued good health

3. Life Extension Super Ubiquinol CoQ10 50mg with Enhanced Mitochondrial Support

Life Extension Super Ubiquinol CoQ10 50mg with Enhanced Mitochondrial Support

- Power Your Heart Health
CoQ10 promotes heart health and cellular energy production. Our formula includes a highly bioavailable ubiquinol form of coenzyme Q10. Plus, we've augmented it with the adaptogen PrimaVie shilajit, which has shown to increase CoQ10 absorption.

- Benefit Go Beyond Your Heart
Your heart cells need CoQ10, but so do your other high-energy organs. That’s why CoQ10 is highly concentrated in your brain, liver and kidneys. It also has powerful antioxidant properties that protect important proteins and mitochondrial DNA from oxidative stress.

- Essential for Youthful Energy
CoQ10 works at the cellular level to help your mitochondria convert sugar and fats in to usable energy. Combining ubiquinol CoQ10 with shilajit–a nutrient discovered in the Himalayas–doubles CoQ10 levels in the mitochondria.

- Ingredients Matter
Sourced using only the finest raw ingredients with the purity and potency your body deserves. This product is certified non-GMO and gluten-free. Manufactured in the USA and a Certificate of Analysis is available for every product we produce.

4.7 out of 5 - more than 2,150 global ratings

Taken twice a day with meals this noticeably improves my blood sugar but this was just a bonus I discovered and not the reason I purchased this.

I purchased this for it's positive effect on heart health and have since discovered it helps boost the immune system, increases energy levels by improving mitochondria function, reduces cholesterol, prevents migraines, and helps with gum disease. I trust Life Extension more than other brands although I am suspect of all of them.

4. Doctor's Best Ubiquinol with Kaneka QH, 100 mg

Doctor's Best Ubiquinol with Kaneka QH, 100 mg


- Ubiquinol with Kaneka Ubiquinol
Contains the reduced form of coenzyme Q10. Both ubiquinol (CoQ10-H2) and ubiquinone (CoQ10) are metabolically active. CoQ10 levels in the heart and body naturally decline after age 40 and the body’s capability to convert CoQ10 to Ubiquinol is reduced.* Each form has unique roles in cells relating to antioxidant actions, supporting healthy heart function and enhancing energy production

- Ubiquinol for Heart Health
Ubiquinol helps support heart health and enhances cellular energy production, needed for our hearts

- Essential for Energy Production 
Coenzyme Q10 helps support mitochondria to enhance cellular energy production.* CoQ10 is a key component in the pathway to produce ATP for energy.* Mitochondria are our body’s primary energy source. Levels of CoQ10 may decline as a healthy person ages

- Helpful to Statin Drug Users 
Statin drugs for high cholesterol have been shown to reduce the body’s CoQ10 levels.* Statins work by blocking the biosynthesis of cholesterol. They also block the production of CoQ10 which leads to reduced ubiquinol levels. CoQ10 levels may drop due to normal aging and to cholesterol-lowering statin drugs

- Bioavailability
Ubiquinol may offer improved bioavailability in aging adults who may have difficulty achieving high levels of this nutrient, or those concerned with nutrient absorption

4.6 out of 5 - more than 1,200 global ratings

I started taking this because I'm a migraine sufferer and COQ10 is proven to be helpful for migraines. I'm 45 and I've read that if you're over 40 you should take Ubiquinol, instead of COQ10 because your body has a harder time converting from COQ10 as you get older. I love that it's also very good for your heart and is recommended by many cardiologists. I trust this brand and find this rubbery pill quite easy to swallow.

5. Theralogix NeoQ10 | Enhanced Absorption Coenzyme Q10 125mg with Vitamin E

NeoQ10 | Enhanced Absorption Coenzyme Q10 125mg with Vitamin E


Best CoQ10 Supplement for Fertility

- Optimal Absorption
VESIsorb colloidal delivery system improves the absorption and bioavailability of CoQ10 by 300-600%, compared to other oil-based CoQ10 supplements.

- Promote Fertility
CoQ10 supports male fertility by promoting healthy sperm motility, and female fertility by supporting healthy egg quality.*

- Heart Health
CoQ10 supports heart health, healthy blood pressure levels, and maintains optimal CoQ10 levels in patients taking a statin.*

- Quality You Can Trust
Made in the USA. Independently tested and certified by NSF, in a cGMP registered facility.

- Dye Free and Gluten Free
Artificial Dye-free. Gluten-free. Gelatin softgels are made from certified BSE-free bovine (cow) gelatin.

4.6 out of 5 - more than 500 global ratings

I used this product for the quality of my eggs. According to the doctor, this helps with the quality of the female eggs.

6. Kirkland Signature Maximum Potency CoQ10 300 mg

Kirkland Signature Maximum Potency CoQ10 300 mg


Kirkland Signature™ CoQ10 300 mg is an antioxidant that is a necessary nutrient for cell function in the body with numerous health benefits.† CoQ10 concentrations may decrease as we age. 

Supplementing with CoQ10 supports heart and antioxidant health and may help support healthy aging.†Supports nerve and muscle health† Supports heart health†Essential in the production of energy† Beneficial for those taking Statin medications†

4.7 out of 5 - more than 1,450 global ratings

I purchased this CoQ10 for my husband as it helps keep his heart in check. I take this as well but in a smaller dose. Would definitely purchase again. We have been taking this for several years now.

7. Qunol CoQ10 Gummies, Qunol CoQ10 100mg

Qunol CoQ10 Gummies, Qunol CoQ10 100mg


Best Coq10 Gummies

- Great Tasting Chewable Gummy 
Qunol CoQ10 Gummies are a delicious alternative to pills. They have 100mg of CoQ10 in convenient, chewable gummies with a delicious orange flavor

- CoQ10 for Heart Health
Your heart, which needs a constant supply of energy, has the highest concentration of CoQ10 of all the tissues in your body. CoQ10 has been shown to help support healthy heart function. Enjoy all the benefits of CoQ10 in an easy to take, chewable gummy

- Antioxidant
CoQ10 acts as antioxidant and helps protect our cells from damaging molecules known as free radicals that may lead to cell damage[1]

- Essential for Energy Production 
CoQ10 plays a vital role in the production of energy in the body. Taking a CoQ10 supplement helps increase natural CoQ10 levels that can be depleted by age and stress

- Ultra High Absoption
Qunol CoQ10 Gummies have water dispersion technology which delivers ultra high absorption

4.7 out of 5 - more than 1,750 global ratings

I randomly chose a coQ10 product, but I didn't expect it to work very well.
My heart is not feeling well and I have radioactive pain in my back.
But when I received a bottle of coQ10 and took one, the pain in my back disappeared the next day, and I felt my heart was much better.

8. Micro Ingredients Water Soluble CoQ10 Powder

Micro Ingredients Water Soluble CoQ10 Powder


Best Coq10 Powder 

- Water Soluble for Higher Absorption
The body is made up of mainly water, so we designed our CoQ10 powder to be water soluble. This gives you a better and faster chance to absorb CoQ10 in full. We wanted to limit the amount of waste, that way you could enjoy the full benefits.

- Promotes Natural Energy Production
We made our natural unflavored powder to hold a high concentration of CoQ10, which gives your body the chance to absorb all of its benefits. Our CoQ10 is also offered in its ubiquinone form to support better effects towards your energy levels.

- Powerful Heart Aid
Each scoop of our product provides a great source of premium CoQ10, it is made to dissolve quick right into any of your favorite beverages. CoQ10 is an essential nutrient that works in the body as a strong antioxidant to aid the heart in proper function and protection.

4.6 out of 5 - more than 400 global ratings

My daughter needs a large amount of C0Q10 for her condition and this works great. I'm able to put it with her other Water-soluble supplements and give it via her Gtube. It doesn't clump or give any issues when using it.

It is a rather large bag so I recommend putting some in an air-tight container and resealing the bag to keep the freshness of the product. 1 bag lasts us 1-2 months, having tried versions this works best for our needs.


a. Who Should Avoid Taking CoQ10?

CoQ10 has possible interaction with anticoagulants. CoQ10 may reduce the effectiveness of blood-thinning medications like warfarin (Jantoven). This could increase the risk of a blood clot.

b. What Happens if Your Coq10 Levels Are Low?

A slight CoQ10 deficiency can result in muscle weakness and fatigue. Although CoQ10 deficiency is unlikely to occur in the general population, there is a higher risk in people with particular medical problems including cancer, diabetes, or genetic abnormalities.

Studies have also shown that a lack of coenzyme Q10 can make cells more vulnerable to harm from free radicals.

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